Aim. To study the efficacy of different algorithms laboratory diagnostics legionellaceae pneumonia in health care organizations. Material and methods. To diagnose used bacteriological examination of bronchoalveolar lavage (BAL), determination of Legionella antigen in urine immunochromatographic method and polymerase chain reaction (PCR). The water samples from the hot water system LPO examined for the presence of Legionella standard bacteriological method. For comparative characteristics of clinical strains of Legionella and strains circulating in the water supply system MPI, used the Dresden panel of monoclonal antibodies and multilocus sequence in accordance with SBT Protocol ELDSNet. Results. Analysis 2 algorithms laboratory diagnosis of Legionnaires ' disease showed that patients with community-acquired pneumonia effective is the combined use of bacteriological method and immunochromatographic urine. For patients on hemodialysis is the optimal combination of PCR analysis IBAL with subsequent bacteriological confirmation of the result. Conclusion. The used algorithm for laboratory diagnosis of Legionnaires ' disease, based on a combination of culture method and PCR seems to be promising for mandatory inclusion in the examination report immunocompromised patients with severe pneumonia. Compared with bacteriological PCR allows for 3-4 days expedite the diagnosis legionellaceae pneumonia, that allows us to start antibiotic therapy. The simplicity and accessibility immunochromatographic method allow to recommend it for all patients severe pneumonia.