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Matushevskaya E.V.

Federal Research and Clinical Center of Specialized Medical Care and Medical Technologies FMBA

Vladimirova E.V.

Academy of postgraduate education under Federal Research and Clinical Center of Specialized Medical Care and Medical Technologies FMBA of Russia

Matushevskaya Yu.I.

Lyubertsy skin and Venereological dispensary

Current topical treatments for acne

Authors:

Matushevskaya E.V., Vladimirova E.V., Matushevskaya Yu.I.

More about the authors

Journal: Russian Journal of Clinical Dermatology and Venereology. 2022;21(5): 589‑594

DOI: 10.17116/klinderma202221051589

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Table of contents

CURRENT TOPICAL TREATMENTS FOR ACNE
CURRENT TOPICAL TREATMENTS FOR ACNE

To cite this article:

Matushevskaya EV, Vladimirova EV, Matushevskaya YuI. Current topical treatments for acne. Russian Journal of Clinical Dermatology and Venereology. 2022;21(5):589‑594. (In Russ.)
https://doi.org/10.17116/klinderma202221051589

Подписка 2026 Клиническая дерматология и венерология (Russian Journal of Clinical Dermatology and Venereology)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

Results of foreign and domestic studies on acne pathogenesis and treatment are presented. In the pathogenesis of acne, one of important factors is the microbiological colonization of the sebaceous glands by C. acnes with subsequent production of inflammatory and chemotactic mediators that trigger dermis inflammation. The main directions in acne treatment based on international and Russian clinical guidelines are addressed. Combination therapy with different drugs (topical antibiotics, retinoids, benzoyl peroxide) is currently recommended to cover the different parts of acne pathogenesis and stages. The role of topical fixed-dose combination therapies for mild to moderately severe acne was described. Based on the analyzed results of the foreign and domestic studies, it is shown that acne treatment with combined medications is effective, safe, and complies with current treatment principles and standards. Several advantages of the clindamycin/benzoyl peroxide combination over other topical acne therapies were shown. The high efficacy, safety, and patient compliance to treatment allow the clindamycin/benzoyl peroxide combination to be recommended for acne treatment in the general practice of the dermatovenerologist.

Keywords:

acne
topical therapy
clindamycin
benzoyl peroxide
combination therapies
clindamycin 1%/benzoyl peroxide 5%

Authors:

Matushevskaya E.V.

Federal Research and Clinical Center of Specialized Medical Care and Medical Technologies FMBA

Vladimirova E.V.

Academy of postgraduate education under Federal Research and Clinical Center of Specialized Medical Care and Medical Technologies FMBA of Russia

Matushevskaya Yu.I.

Lyubertsy skin and Venereological dispensary

Received:

03.08.2022

Accepted:

10.09.2022

Close metadata

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