Atopic dermatitis (AtD) is an important medical and social problem, the topicality of which is determined by the rising incidence rate, chronic and remittent course of the disease, and difficulties in choosing a treatment method. According to the World Health Organization (WHO) and the World Allergy Organization (WAO), AD ranks fourth among the socially significant pathologies. Aim. The aim of this study was to analyze mistakes made by dermatovenereologists upon examination of young males of the military age with the endogenous form of AtD, evaluation of the diagnostic value of the eosinophil cation protein (ЕСР) and Phadiatop tests, and selection of the treatment tactics. Material and methods. The study was conducted at the Chair of Skin and Venereal Diseases with the Cosmetology Course, the Physicians’ Continuing Education Institute of the Moscow State University of Food Industry. Three young males at the age of 18, 18, and 19 years were examined. All they were liable for military service in the Armed Forces (AF) of the Russian Federation. They had minimal eruptions on their skin, not always similar to typical AtD manifestations. When examined in the local medical center, the males had the normal level of total IgE. Results. The main results of the three clinical observations indicate that the endogenous form of AtD occurs in the dermatological practice. The normal value of total IgE not always indicates the absence of atopia in the patient. Conclusion Diagnostic errors often result in the late correct diagnosis and formation of atopic march. The use of the highly informative test Phadiatop and identification of ЕСР enable a timely diagnosis of the endogenous form of AtD and timely administration of appropriate therapy. The combined three-component topical corticosteroid Acriderm GK, containing betamethasone, gentamycin, and clotrimazol, has the pronounced antimycotic, antibacterial, and anti-inflammatory action. This is especially important in treatment of AtD, the pathogenesis of which is determined by the staphylococcus superantigen, lipophilic yeasts of the Malassezia genus, and yeast-like fungi of the Candida spp. genus, colonizing the skin and mucosa.