Prospects for stromal-vascular fraction in the treatment of lower limb ischemia

Nekrasov D.A.; Puzanov A.I.

doi:https://doi.org/10.17116/hirurgia202511274

Nekrasov D.A.

Petrovsky National Research Center of Surgery

ORCID: 0000-0002-8179-2059

Puzanov A.I.

Petrovsky National Research Center of Surgery

ORCID: 0009-0002-2612-2594

Prospects for stromal-vascular fraction in the treatment of lower limb ischemia

Authors:

Nekrasov D.A., Puzanov A.I.

More about the authors

Journal: Pirogov Russian Journal of Surgery. 2025;(11‑2): 74‑78

DOI: 10.17116/hirurgia202511274

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To cite this article:

Nekrasov DA, Puzanov AI. Prospects for stromal-vascular fraction in the treatment of lower limb ischemia. Pirogov Russian Journal of Surgery. 2025;(11‑2):74‑78. (In Russ.)
https://doi.org/10.17116/hirurgia202511274

Подписка 2026 Хирургия. Журнал им. Н.И. Пирогова (Pirogov Russian Journal of Surgery)

Использование инфографики авторами научных работ

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Abstract:

Stromal vascular fraction is a heterogeneous cell population with significant regenerative potential harvested from adipose tissue. Its cells stimulate angiogenesis, have anti-apoptotic and anti-inflammatory effects, stimulate cell growth and differentiation. This review highlights the mechanisms of action, as well as possibilities and results of local application of stromal vascular fraction in lower limb ischemia. Prospects of stromal vascular fraction for the treatment of lower limb ischemia are presented.

Keywords:

stromal vascular fraction

lower limb ischemia

Authors:

Nekrasov D.A.

Petrovsky National Research Center of Surgery

ORCID: 0000-0002-8179-2059

Puzanov A.I.

Petrovsky National Research Center of Surgery

ORCID: 0009-0002-2612-2594

Received:

23.09.2025

Accepted:

12.10.2025

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References:

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