The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-4329
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2025
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Egorov A.V.

Sechenov First Moscow State Medical University (Sechenov University)

Zhemerikin G.A.

Sechenov First Moscow State Medical University (Sechenov University)

Bezrukov E.A.

Sechenov First Moscow State Medical University (Sechenov University)

Steinbock V.S.

Sechenov First Moscow State Medical University (Sechenov University)

Vetshev F.P.

Sechenov First Moscow State Medical University (Sechenov University)

Targyn A.A.

Sechenov First Moscow State Medical University (Sechenov University)

Davudova A.A.

Sechenov First Moscow State Medical University (Sechenov University)

Ziegler G.J.

Sechenov First Moscow State Medical University (Sechenov University)

Cystic-solid transformation of the pancreas and kidneys due to von Hippel-Lindau disease

Authors:

Egorov A.V., Zhemerikin G.A., Bezrukov E.A., Steinbock V.S., Vetshev F.P., Targyn A.A., Davudova A.A., Ziegler G.J.

More about the authors

Journal: Pirogov Russian Journal of Surgery. 2025;(10): 118‑125

DOI: 10.17116/hirurgia2025101118

Read: 396 times

Buy for 300₽
Contact the author
Table of contents

CYSTIC-SOLID TRANSFORMATION OF THE PANCREAS AND KIDNEYS DUE TO VON HIPPEL-LINDAU DISEASE
CYSTIC-SOLID TRANSFORMATION OF THE PANCREAS AND KIDNEYS DUE TO VON HIPPEL-LINDAU DISEASE

To cite this article:

Egorov AV, Zhemerikin GA, Bezrukov EA, et al. . Cystic-solid transformation of the pancreas and kidneys due to von Hippel-Lindau disease. Pirogov Russian Journal of Surgery. 2025;(10):118‑125. (In Russ.)
https://doi.org/10.17116/hirurgia2025101118

Подписка 2026 Хирургия. Журнал им. Н.И. Пирогова (Pirogov Russian Journal of Surgery)
МСФ на ЯМ
Использование инфографики авторами научных работ
Recommended articles:
Stereotactic radiotherapy of spinal hema­ngioblastoma. Burdenko's Journal of Neurosurgery. 2024;(6):63-70
Clinical case of successful pregnancy in a patient with ecto­pic ACTH syndrome after radi­cal surgical treatment. Russian Journal of Human Reproduction. 2024;(6):118-123
Analysis of dyna­mics and fore­cast of morbidity of diseases of the urogenital system in the child popu­lation living in the Repu­blic of Sakha (Yakutia). Russian Journal of Preventive Medi­cine. 2025;(3):60-66
Neuroendocrine tumor of the pancreas with liver meta­stases. Case report. Russian Journal of Evidence-Based Gastroenterology. 2025;(2):106-114
Surgical mana­gement of patients with local recu­rrence of renal cancer. Prognostic factors of survival. P.A. Herzen Journal of Onco­logy. 2025;(3):20-24
Abstract:

The authors discuss treatment of 11 patients with extremely rare hereditary von Hippel-Lindau syndrome, who were observed for 2 years. Two cases are presented with discussion of modern approaches to diagnosis and surgical tactics for damage to the pancreas and kidneys.

Keywords:

von Hippel-Lindau disease
pancreas
kidneys
neuroendocrine tumor
cystadenoma
cyst
renal cell carcinoma

Authors:

Egorov A.V.

Sechenov First Moscow State Medical University (Sechenov University)

Zhemerikin G.A.

Sechenov First Moscow State Medical University (Sechenov University)

Bezrukov E.A.

Sechenov First Moscow State Medical University (Sechenov University)

Steinbock V.S.

Sechenov First Moscow State Medical University (Sechenov University)

Vetshev F.P.

Sechenov First Moscow State Medical University (Sechenov University)

Targyn A.A.

Sechenov First Moscow State Medical University (Sechenov University)

Davudova A.A.

Sechenov First Moscow State Medical University (Sechenov University)

Ziegler G.J.

Sechenov First Moscow State Medical University (Sechenov University)

Received:

20.01.2025

Accepted:

10.02.2025

Close metadata

References:

  1. Lonser RR, Glenn GM, Walther M, et all. von Hippel-Lindau disease. https://doi.org/10.1016/S0140-6736(03)13643-4
  2. Shanbhogue K.P., Hoch M., Fatterpaker G. et all. von Hippel-Lindau Disease: Review of Genetics and Imaging. Radiologic Clinics of North America. Vol 54, Issue 3, May 2016, Pages 409-422.  https://doi.org/10.1016/j.rcl.2015.12.004
  3. Aronow M.E., Henry E Wiley H.E., Alain Gaudric A. et all. VON HIPPEL-LINDAU DISEASE: Update on Pathogenesis and Systemic Aspects. Retina. 2019 Dec;39(12):2243-2253. https://doi.org/10.1097/IAE.0000000000002555
  4. Gómez-Virgilio L, Velazquez-Paniagua M, Cuazozon-Ferrer L, et all. Genetics, Pathophysiology, and Current Challenges in Von Hippel-Lindau Disease Therapeutics. Diagnostics (Basel). 2024 Aug. PMID: 39272694; PMCID: PMC11393980. https://doi.org/10.3390/diagnostics14171909
  5. Maher ER, Iselius L, Yates JR, Littler M, Benjamin C, Harris R, Sampson J, Williams A, Ferguson-Smith MA, Morton N. Von Hippel-Lindau disease: a genetic study. J MedGenet. 1991;28: 443-7.  https://doi.org/10.1136/jmg.28.7.443
  6. Strugov VV, Rybnikova AV. Von Hippel-Lindau syndrome: [Electronic resource]//GENOKARTA Genetic Encyclopedia. 2019. (In Russ.). https://www.genokarta.ru/disease/Sindrom_fon_Hippelya_Lindau.
  7. Gläsker S, Krüger MT, Klingler JH, Wlodarski M, Klompen J, Schatlo B, Hippchen B, Neumann HP, Van Velthoven V. Hemangioblastomas and neurogenicpolyglobulia. Neurosurgery. 2013;72:930-935.  https://doi.org/10.1227/NEU.0b013e31828ba793
  8. Gläsker S, Neumann HPH, Koch CA, et all. von Hippel-Lindau Disease. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000.2018 Sep 12.  https://doi.org/10.1055/s-0036-1579757
  9. Krauss T, Ferrara AM, Links TP et all. Preventive medicine of von Hippel-Lindau disease-associated pancreatic neuroendocrine tumors. EndocrRelatCancer. 2018;25:783-93.  https://doi.org/10.1530/ERC-18-0100
  10. Larcher A, Rowe I, Belladelli F. et all. Von Hippel-Lindau disease-associated renal cell carcinoma: a call to action. Curr Opin Urol. 2022 Jan 1;32(1):31-39.  https://doi.org/10.1097/MOU.0000000000000950
  11. Chittiboina P, Lonser RR. Von Hippel-Lindau disease. Handb Clin Neurol. 2015;132:139-56.  https://doi.org/10.1016/B978-0-444-62702-5.00010-X
  12. Stegura D.S., Konovalov R.N., Krotenkova M.V., et al. Multimodal approach to the diagnosis of von Hippel-Lindau disease. Clinical case. Radiology — practice. 2022;(2):84-93. (In Russ.). https://doi.org/10.52560/2713-0118-2022-2-84-93
  13. Fernandes DA, Mourão JLV, Duarte JÁ, et all. Imaging manifestations of von Hippel-Lindau disease: an illustrated guide focusing on abdominal manifestations. Radiol Bras. 2022 Sep-Oct;55(5):317-323. PMID: 36320367; PMCID: PMC9620840. https://doi.org/10.1590/0100-3984.2021.0121-en
  14. Untanas A, Trakymas M, Lekienė I, Briedienė R. Von Hippel-Lindau syndrome and renal tumours: radiological diagnostic and treatment options. A case report and literature review. Acta Med Litu. 2020;27(1):25-32. PMID: 32577093; PMCID: PMC7305806. https://doi.org/10.6001/actamedica.v27i1.4263
  15. Capogrosso, P., et al. Follow-up After Treatment for Renal Cell Carcinoma: The Evidence Beyond the Guidelines. Eur Urol Focus. 2016;1:272.  https://doi.org/10.1016/j.euf.2015.04.001
  16. Defortescu, G., et al. Diagnostic performance of contrast-enhanced ultrasonography and magnetic resonance imaging for the assessment of complex renal cysts: A prospective study. Int J Urol. 2017;24:184.  https://doi.org/10.1111/iju.13289
  17. Israel GM, Hindman N, Bosniak MA. Evaluation of cystic renal masses: comparison of CT and MR imaging by using the Bosniak classification system. Radiology. 2004. May; 231(2): 365—71.  https://doi.org/10.1148/radiol.2312031025
  18. Sharma A, Mukewar S, Vege SS. Clinical profile of pancreatic cystic lesions in von Hippel-Lindau disease: a series of 48 patients seen at a tertiary institution. Pancreas. 2017;46:948-52.  https://doi.org/10.1097/MPA.0000000000000875
  19. Egorov V.I., Perov R.V., Beltsevich D.G., Starostina N.S. Surgery of hereditary tumor syndromes. Unique experience of organ-preserving and extensive pancreatic resections for von Hippel-Lindau syndrome in a multidisciplinary city hospital. Bakhrushin Brothers City Clinical Hospital. ERC.XX1 Russian Oncology Congress: Abstracts. (In Russ.).
  20. Dickson PV, Alex GC, Grubbs EG, Ayala-Ramirez M, Jimenez C, Evans DB, Lee JE, Perrier ND. Posterior retroperitoneoscopic adrenalectomy is a safe and effective alternative to transabdominal laparoscopic adrenalectomy for pheochromocytoma. Surgery. 2011;150:452-8.  https://doi.org/10.1016/j.surg.2011.07.004
  21. Shingleton WB, Sewell PE Jr. Percutaneous renal cryoablation of renal tumors in patients with von Hippel-Lindau disease. J Urol. 2002;167:1268-70. PMID: 11832711 
  22. Grubb RL III, Choyke PL, Pinto PA, Linehan WM, Walther MM. Management of von Hippel-Lindau-associated kidney cancer. Nat ClinPract Urol. 2005;2:248-55.  https://doi.org/10.1038/ncpuro0179
  23. Bersang AB, Sondergaard Mosholt KS, Verner Jensen C, et all. Safety and oncological outcome following radiofrequency ablation of small renal masses in a single center. Scandinavian journal of urology, 2021. https://doi.org/10.1080/21681805.2021.1900386
Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.