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Alkhasov A.B.

National Medical Research Center for Children’s Health

Gurskaya A.S.

National Medical Research Center for Children’s Health

Bayazitov R.R.

National Medical Research Center for Children’s Health

Nakovkin O.N.

National Medical Research Center for Children’s Health

Sulavko M.A.

National Medical Research Center for Children’s Health

Karnuta I.V.

National Medical Research Center for Children’s Health

Ekimovskaya E.V.

National Medical Research Center for Children’s Health

Kyarimov I.A.

National Medical Research Center for Children’s Health

Akhmedova D.M.

National Medical Research Center for Children’s Health

Klepikova A.A.

National Medical Research Center for Children’s Health

Ratnikov S.A.

National Medical Research Center for Children’s Health

Fisenko A.P.

National Medical Research Center for Children’s Health

Choledochal cysts: surgical treatment in newborns and infants

Authors:

Alkhasov A.B., Gurskaya A.S., Bayazitov R.R., Nakovkin O.N., Sulavko M.A., Karnuta I.V., Ekimovskaya E.V., Kyarimov I.A., Akhmedova D.M., Klepikova A.A., Ratnikov S.A., Fisenko A.P.

More about the authors

Journal: Pirogov Russian Journal of Surgery. 2024;(3): 5‑13

DOI: 10.17116/hirurgia20240315

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Table of contents

CHOLEDOCHAL CYSTS: SURGICAL TREATMENT IN NEWBORNS AND INFANTS
CHOLEDOCHAL CYSTS: SURGICAL TREATMENT IN NEWBORNS AND INFANTS

To cite this article:

Alkhasov AB, Gurskaya AS, Bayazitov RR, et al. . Choledochal cysts: surgical treatment in newborns and infants. Pirogov Russian Journal of Surgery. 2024;(3):5‑13. (In Russ.)
https://doi.org/10.17116/hirurgia20240315

Подписка 2026 Хирургия. Журнал им. Н.И. Пирогова (Pirogov Russian Journal of Surgery)
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Abstract:

OBJECTIVE

To improve postoperative outcomes in newborns and infants with choledochal cysts and to determine the indications for surgery.

MATERIAL AND METHODS

There were 13 children aged 0—3 months with choledochal cyst who underwent reconstructive surgery between 2019 and 2023. In all children, choledochal cyst was associated with cholestasis. Acholic stool was observed in almost half of the group (n=7). All children underwent cyst resection and Roux-en-Y hepaticoenterostomy.

RESULTS

Symptoms of cholestasis regressed in all patients. Mean surgery time was 128±27 min. There were no complications. Enteral feeding was started after 1—2 postoperative days, abdominal drainage was removed after 6.2±1.6 days. Mean length of hospital-stay was 16±3.7 days. Adequate bile outflow is one of the main principles. For this purpose, anastomosis with intact tissues of hepatic duct should be as wide as possible. Roux-en-Y loop should be at least 40—60 cm to prevent postoperative cholangitis.

CONCLUSION

Drug-resistant cholestasis syndrome and complicated choledochal cysts (cyst rupture, bile peritonitis) are indications for surgical treatment in newborns and infants. When forming Roux-en-Y hepaticoenterostomy, surgeon should totally excise abnormal tissues of the biliary tract to prevent delayed malignant transformation.

Keywords:

choledochal cyst
newborns
hepaticoenterostomy

Authors:

Alkhasov A.B.

National Medical Research Center for Children’s Health

Gurskaya A.S.

National Medical Research Center for Children’s Health

Bayazitov R.R.

National Medical Research Center for Children’s Health

Nakovkin O.N.

National Medical Research Center for Children’s Health

Sulavko M.A.

National Medical Research Center for Children’s Health

Karnuta I.V.

National Medical Research Center for Children’s Health

Ekimovskaya E.V.

National Medical Research Center for Children’s Health

Kyarimov I.A.

National Medical Research Center for Children’s Health

Akhmedova D.M.

National Medical Research Center for Children’s Health

Klepikova A.A.

National Medical Research Center for Children’s Health

Ratnikov S.A.

National Medical Research Center for Children’s Health

Fisenko A.P.

National Medical Research Center for Children’s Health

Received:

20.09.2023

Accepted:

21.10.2023

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References:

  1. Soares KC, Arnaoutakis DJ, Kamel I, Rastegar N, Anders R, Maithel S, Pawlik TM. Choledochal cysts: presentation, clinical differentiation, and management. Journal of the American College of Surgeons. 2014;219:1167-1180. https://doi.org/10.1016/j.jamcollsurg.2014.04.023
  2. Tannuri U, Pessoa JH, Sakane PT, Gonçalves ME, Bedoni F. Biliary tract dilatation and abnormal choledocho-pancreatic ductal junction in children. Journal of Pediatrics. 1994;70(6):359-364. 
  3. Gadelhak N, Shehta A, Hamed H. Diagnosis and management of choledochal cyst: 20 years of single center experience. World Journal of Gastroenterology. 2014;20(22):7061-7066. https://doi.org/10.3748/wjg.v20.i22.7061
  4. Singham J, Schaeffer D, Yoshida E, Scudamore C. Choledochal cysts: analysis of disease pattern and optimal treatment in adult and paediatric patients. HPB. 2007;9(5):383-387.  https://doi.org/10.1080/13651820701646198
  5. Diao M, Li L, Cheng W. Timing of surgery for prenatally diagnosed asymptomatic choledochal cysts: A prospective randomized study. Journal of Pediatric Surgery. 2012;47:506-512.  https://doi.org/10.1016/j.jpedsurg.2011.09.056
  6. Ishibashi H, Shimada M, Kamisawa T, Fujii H, Hamada Y, Kubota M, Urushihara N, Endo I, Nio M, Taguchi T, Ando H; Japanese Study Group on Congenital Biliary Dilatation (JSCBD). Japanese clinical practice guidelines for congenital biliary dilatation. Journal of Hepato-biliary-Pancreatic Sciences. 2017;24(1):1-16.  https://doi.org/10.1002/jhbp.415
  7. She WH, Chung HY, Lan LC, Wong KK, Saing H, Tam PK. Management of choledochal cyst: 30 years of experience and results in a single center. Journal of Pediatric Surgery. 2009;44:2307-2311. https://doi.org/10.1016/j.jpedsurg.2009.07.071
  8. Okada T, Honda S, Miyagi H, Kubota KC, Cho K, Taketomi A. Liver fibrosis in prenatally diagnosed choledochal cysts. Journal of Pediatric Gastroenterology and Nutrition. 2013;57:e14.  https://doi.org/10.1097/MPG.0b013e3182973579
  9. Diao M, Li L, Cheng W. Timing of surgery for prenatally diagnosed asymptomatic choledochal cysts: A prospective randomized study. Journal of Pediatric Surgery. 2012;47:506-512.  https://doi.org/10.1016/j.jpedsurg.2011.09.056
  10. Diao M, Li L. Pediatric minimal invasive surgery-bile duct diseases. Annals of Laparoscopic and Endoscopic Surgery. 2018;3:100.  https://doi.org/10.21037/ales.2018.11.07
  11. Guan X, Li J, Wang Z, Zeng J, Zhong W, Yu J. Timing of operation in children with a prenatal diagnosis of choledochal cyst: A single-center retrospective study. Journal of Hepato-biliary-Pancreatic Sciences. 2022;29:1308-1315. https://doi.org/10.1002/jhbp.1155
  12. Okada T, Sasaki F, Ueki S, Hirokata G, Okuyama K, Cho K, Todo S. Postnatal management for prenatally diagnosed choledochal cysts. Journal of Pediatric Surgery. 2004;39:1055-1058. https://doi.org/10.1016/j.jpedsurg.2004.03.054
  13. Suita S, Shono K, Kinugasa Y, Kubota M, Matsuo S. Influence of age on the presentation and outcome of choledochal cyst. Journal of Pediatric Surgery. 1999;34:1765-1768. https://doi.org/10.1016/s0022-3468(99)90308-1
  14. Chen CJ. Clinical and operative findings of choledochal cysts in neonates and infants differ from those in older children. Asian Journal of Surgery. 2003;26:213-217.  https://doi.org/10.1016/S1015-9584(09)60306-7
  15. Liu SL, Li L, Hou WY, Zhang J, Huang LM, Li X, Xie HW, Cheng W. Laparoscopic excision of choledochal cyst and Roux-en-Y hepaticojejunostomy in symptomatic neonates. Journal of Pediatric Surgery. 2009;44:508-511.  https://doi.org/10.1016/j.jpedsurg.2008.08.006
  16. Saito T, Terui K, Mitsunaga T, Nakata M, Kuriyama Y, Higashimoto Y, Kouchi K, Onuma N, Takahashi H, Yoshida H. Role of pediatric endoscopic retrograde cholangiopancreatography in an era stressing less-invasive imaging modalities. Journal of Pediatric Gastroenterology and Nutrition. 2014;59:204-209.  https://doi.org/10.1097/MPG.0000000000000399
  17. Chen TY, Wang HK, Yeh ML, Wei SH, Lu K. Subdural hemorrhage as a first symptom in an infant with a choledochal cyst: Case report. Journal of Neurosurgery: Pediatrics. 2012;9:414-416.  https://doi.org/10.3171/2011.12.PEDS11279
  18. Fumino S, Iwai N, Deguchi E, Shimadera S, Iwabuchi T, Nishimura T, Ono S. Bleeding tendency as a first symptom in children with congenital biliary dilatation. European Journal of Pediatric Surgery. 2007;17:2-5.  https://doi.org/10.1055/s-2007-964928
  19. Scalise PN, Yang A, Neumeyer C, Perez-Atayde AR, Robinson JR, Kim HB, Cuenca AG. Prenatal diagnosis of rapidly enlarging choledochal cyst with gastric outlet obstruction. Journal of Surgery Case Reports. 2021;rjab547. https://doi.org/10.1093/jscr/rjab547
  20. Winkler RE, Lancry K, Velcek FT. Choledochal cyst with perforation--an unusual presentation. Case report and review of the literature. South African Journal of Surgery. 2001;39:95-96. 
  21. Lal R, Agarwal S, Shivhare R, Kumar A, Sikora SS, Kapoor VK, Saxena R. Management of complicated choledochal cysts. Digestive Surgery. 2007;24:456-462.  https://doi.org/10.1159/000111821
  22. Tainaka T, Shirota C, Sumida W, Yokota K, Makita S, Amano H, Okamoto M, Takimoto A, Kano Y, Yasui A, Nakagawa Y, Hinoki A, Uchida H. Laparoscopic definitive surgery for choledochal cyst is performed safely and effectively in infants. Journal of Minimal Access Surgery. 2022;18:372-377.  https://doi.org/10.4103/jmas.JMAS_98_21
  23. Berkowitz CL, Peters AW, Stratigis JD, Barone PD, Kadenhe-Chiweshe AV, Oh PS. Cystic biliary anomaly in a newborn with features of choledochal cyst and cystic biliary atresia. Journal of Pediatric Surgery Case Reports. 2021;66:101781. https://doi.org/10.1016/j.epsc.2021.101781
  24. Tessier MEM, Shneider BL. 60 Days in Biliary Atresia: A Historical Dogma Challenged. Clinics in Liver Disease. 2020;15:3-7.  https://doi.org/10.1002/cld.843
  25. Ten Hove A, de Meijer VE, Hulscher JBF, de Kleine RHJ. Meta-analysis of risk of developing malignancy in congenital choledochal malformation. British Journal of Surgery. 2018;105:482-490.  https://doi.org/10.1002/bjs.10798
  26. Soares KC, Kim Y, Spolverato G, Maithel S, Bauer TW, Marques H, Sobral M, Knoblich M, Tran T, Aldrighetti L, Jabbour N, Poultsides GA, Gamblin TC, Pawlik TM. Presentation and Clinical Outcomes of Choledochal Cysts in Children and Adults: A Multi-institutional Analysis. JAMA Surgery. 2015;150:577-584.  https://doi.org/10.1001/jamasurg.2015.0226
  27. Schukfeh N, Abo-Namous R, Madadi-Sanjani O, Uecker M, Petersen C, Ure BM, Kuebler JF. The Role of Laparoscopic Treatment of Choledochal Malformation in Europe: A Single-Center Experience and Review of the Literature. European Journal of Pediatric Surgery. 2022;32:521-528.  https://doi.org/10.1055/s-0042-1749435
  28. Koroleva AA. Diagnostika i vybor metoda khirurgicheskogo lecheniya kistoznykh transformatsiy zhelchnykh protokov u vzroslykh: Dis. ... kand. med. nauk. M. 2017. (In Russ.).
  29. Razumovsky AYu, Mitupov ZB, Kulikova NV, Stepanenko NS, Zadvernyuk AS, Titova EA, Shubin NV. Efficiency of minilaparotomy in the treatment of choledochal malformation in children. Khirurgiya. Zurnal im. N.I. Pirogova. 2021;(5):63-71. (In Russ.). https://doi.org/10.17116/hirurgia202105163
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