Efficacy of percutaneous mechanical thrombectomy for proximal deep vein thrombosis

Sukovatykh B.S.; Sereditsky A.V.; Muradyan V.F.; Azarov A.M.; Sukovatykh M.B.; Lapinas A.A.; Khachatryan A.R.

doi:https://doi.org/10.17116/hirurgia202205175

Sukovatykh B.S.

Kursk State Medical University

SPIN RSCI: 8778-1530
Scopus AuthorID: 7004581366
ORCID: 0000-0003-2197-8756

Sereditsky A.V.

Kursk State Medical University

ORCID: 0000-0003-3303-1308

Muradyan V.F.

Orel Regional Clinical Hospital

ORCID: 0000-0002-0746-9931

Azarov A.M.

Orel Regional Clinical Hospital

ORCID: 0000-0001-5470-5688

Sukovatykh M.B.

Kursk State Medical University

ORCID: 0000-0003-1907-4395

Lapinas A.A.

Orel Regional Clinical Hospital

ORCID: 0000-0001-7185-0430

Khachatryan A.R.

Orel Regional Clinical Hospital

Efficacy of percutaneous mechanical thrombectomy for proximal deep vein thrombosis

Authors:

Sukovatykh B.S., Sereditsky A.V., Muradyan V.F., Azarov A.M., Sukovatykh M.B., Lapinas A.A., Khachatryan A.R.

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Journal: Pirogov Russian Journal of Surgery. 2022;(5): 75‑80

DOI: 10.17116/hirurgia202205175

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To cite this article:

Sukovatykh BS, Sereditsky AV, Muradyan VF, Azarov AM, Sukovatykh MB, Lapinas AA, Khachatryan AR. Efficacy of percutaneous mechanical thrombectomy for proximal deep vein thrombosis. Pirogov Russian Journal of Surgery. 2022;(5):75‑80. (In Russ.)
https://doi.org/10.17116/hirurgia202205175

Подписка 2026 Хирургия. Журнал им. Н.И. Пирогова (Pirogov Russian Journal of Surgery)

Использование инфографики авторами научных работ

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OBJECTIVE

To study the efficacy and safety of percutaneous mechanical thrombectomy and long-term anticoagulation with rivaroxaban for proximal deep vein thrombosis.

MATERIAL AND METHODS

We analyzed the effectiveness of treatment in 60 patients with proximal deep vein thrombosis divided into 2 homogeneous groups by 30 people. Standard therapy was performed in the first group, therapy with percutaneous mechanical thrombectomy was applied in the second group. Patients received rivaroxaban in preoperative, perioperative and 6-month postoperative period. We considered complications of endovascular treatment and anticoagulation. Ultrasound and clinical examination were carried out after 12 months to analyze restoration of deep vein patency and venous outflow disorders. Recovery of vein lumen was assessed as follows: <50% — minimal, 50—99% — partial, 100% — complete.

RESULTS

Recurrent deep vein thrombosis was found in 2 (6.7%) patients of the second group. Hemorrhagic complications following rivaroxaban therapy occurred in 8 (13.3%) patients (equally in both groups). In the first group, complete restoration of vein lumen was found in 16.7% of patients, partial recovery — in 40%, minimal recovery — in 43.3% of patients. In the second group, these values were 16.7%, 60% and 23.3%, respectively. Severe venous outflow impairment developed in 43.3% of patients in the first group and 23.3% of patients in the second group. Moderate impairment occurred in 30% and 20% of patients, mild disorders — in 10% and 40% of patients, respectively.

CONCLUSION

Percutaneous mechanical thrombectomy on the background of long-term anticoagulation with rivoroxaban improves treatment outcomes in patients with proximal deep vein thrombosis.

Keywords:

proximal thrombosis

deep veins

lower limbs

percutaneous endovascular thrombectomy

rivaroxaban

Authors:

Sukovatykh B.S.

Kursk State Medical University

SPIN RSCI: 8778-1530
Scopus AuthorID: 7004581366
ORCID: 0000-0003-2197-8756

Sereditsky A.V.

Kursk State Medical University

ORCID: 0000-0003-3303-1308

Muradyan V.F.

Orel Regional Clinical Hospital

ORCID: 0000-0002-0746-9931

Azarov A.M.

Orel Regional Clinical Hospital

ORCID: 0000-0001-5470-5688

Sukovatykh M.B.

Kursk State Medical University

ORCID: 0000-0003-1907-4395

Lapinas A.A.

Orel Regional Clinical Hospital

ORCID: 0000-0001-7185-0430

Khachatryan A.R.

Orel Regional Clinical Hospital

Received:

31.05.2021

Accepted:

22.09.2021

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