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Kit O.I.

National Medical Oncology Research Center

Kolesnikov E.N.

National Medical Research Center of Oncology

Kozhushko M.A.

National Medical Research Center of Oncology

Meshcheryakova M.Yu.

National Medical Research Center of Oncology

Esophageal squamous cell carcinoma localized in pharyngeal-esophageal diverticulum

Authors:

Kit O.I., Kolesnikov E.N., Kozhushko M.A., Meshcheryakova M.Yu.

More about the authors

Journal: Pirogov Russian Journal of Surgery. 2022;(4): 105‑109

DOI: 10.17116/hirurgia2022041105

Read: 1329 times

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Table of contents

ESOPHAGEAL SQUAMOUS CELL CARCINOMA LOCALIZED IN PHARYNGEAL-ESOPHAGEAL DIVERTICULUM
ESOPHAGEAL SQUAMOUS CELL CARCINOMA LOCALIZED IN PHARYNGEAL-ESOPHAGEAL DIVERTICULUM

To cite this article:

Kit OI, Kolesnikov EN, Kozhushko MA, Meshcheryakova MYu. Esophageal squamous cell carcinoma localized in pharyngeal-esophageal diverticulum. Pirogov Russian Journal of Surgery. 2022;(4):105‑109. (In Russ.)
https://doi.org/10.17116/hirurgia2022041105

Подписка 2026 Хирургия. Журнал им. Н.И. Пирогова (Pirogov Russian Journal of Surgery)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

Squamous cell carcinoma in Zenker’s diverticulum was first described in 1933. No large studies have yet been conducted due to rarity of this disease. There are a lot of unresolved issues regarding diagnosis and treatment of this pathology. In the literature, there are only few reports on cancer of Zenker diverticulum. It is only known that clinical symptoms are not specific, and diagnosis of carcinoma is traditionally correlated with age and male sex. Despite esophageal localization of primary tumor, its development can take up to 10 years. The authors report squamous cell carcinoma in Zenker diverticulum, discuss the main difficulties of morphological verification of this disease and choice of surgical approach.

Keywords:

Zenker’s diverticulum
squamous cell carcinoma
transcervical diverticulectomy

Authors:

Kit O.I.

National Medical Oncology Research Center

Kolesnikov E.N.

National Medical Research Center of Oncology

Kozhushko M.A.

National Medical Research Center of Oncology

Meshcheryakova M.Yu.

National Medical Research Center of Oncology

Received:

04.07.2021

Accepted:

21.09.2021

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References:

  1. Kit OI, Kolesnikov EN, Maksimov AYu, Snezhko AV, Averkin MA. Description of a case of metachronous cancer of the cervical esophagus after extirpation of the esophagus with pre-thoracic esophagoplasty of the right half of the colon. Voprosy onkologii. 2018;64(2):249-252. (In Russ.).
  2. Khan AS, Dwivedi RC, Khan AS, Thway K, Fisher C, Rhys-Evans PH. Carcinoma arising from pharyngeal diverticula. Head Neck. 2011;33(1):135-137.  https://doi.org/10.1002/hed.21259
  3. Fox SS, Nagasawa KK, Williams ZF. Incidental Squamous Cell Carcinoma In Situ in a Large Pharyngoesophageal (Zenker’s) Diverticulum. Am Surg. 2017;83(8):288-290. 
  4. Acar T, Savas R, Kocacelebi K, Ersoz G. Squamous cell carcinoma arising from a Zenker’s diverticulum: contribution of FDG-PET/CT to the diagnosis. Dis Esophagus. 2016;29(8):1170-1171. https://doi.org/10.1111/dote.12406
  5. Hajjar WM, Almutairi OT, Jameel MA, Al-Nassar SA, Raddaoui E, Hajjar AW. Squamous Cell Carcinoma Arising in Zenker’s Diverticulum: A Case Report and Review of the Literature. Turk Thorac J. 2018;19(4):228-230.  https://doi.org/10.5152/TurkThoracJ.2018.17082
  6. Dionigi G, Sessa F, Rovera F, Boni L, Carrafiello G, Dionigi R. Ten year survival after excision of squamous cell cancer in Zenker’s diverticulum: report of a case. World J Surg Oncol. 2006;4(17):1-4.  https://doi.org/10.1186/1477-7819-4-17
  7. Huang BS, Unni KK, Payne WS. Long-term survival following diverticulectomy for cancer in pharyngoesophageal (Zenker’s) diverticulum. Ann Thorac Surg. 1984;38(3):207-210.  https://doi.org/10.1016/s0003-4975(10)62238-2
  8. Noel Z, Hoeller S, Bihl M, Muller L. TP53 and PTEN as driver mutations in Zenker’s carcinoma-a clinical presentation. Clin Case Rep. 2020;8(12):2791-2797. https://doi.org/10.1002/ccr3.3169
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