The variants of enteral distress syndrome correction with peritonitis

Vlasov A.P.; Salakhov E.K.; Markin O.V.; Vlasova T.I.; Muratova T.A.; Vilkov A.V.; Sitdikov I.I.; Levkin K.I.

doi:https://doi.org/10.17116/hirurgia202202150

Vlasov A.P.

Ogarev Mordovia State University

ORCID: 0000-0003-4731-2952

Salakhov E.K.

Mendeleevsk Central District Hospital

ORCID: 0000-0003-2119-8020

Markin O.V.

Ogarev Mordovia State University

ORCID: 0000-0002-1027-1408

Vlasova T.I.

Ogarev Mordivia State University

ORCID: 0000-0002-2624-6450

Muratova T.A.

Ogarev National Research Mordovia State University

Vilkov A.V.

Ogarev Mordovia State University

ORCID: 0000-0002-7493-109X

Sitdikov I.I.

National Research Mordovian State University N.P. Ogarev of the Ministry of Education and Science Russia

Levkin K.I.

N.P. Ogareva National Research Mordovian State University

The variants of enteral distress syndrome correction with peritonitis

Authors:

Vlasov A.P., Salakhov E.K., Markin O.V., Vlasova T.I., Muratova T.A., Vilkov A.V., Sitdikov I.I., Levkin K.I.

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Journal: Pirogov Russian Journal of Surgery. 2022;(2): 50‑56

DOI: 10.17116/hirurgia202202150

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To cite this article:

Vlasov AP, Salakhov EK, Markin OV, et al. . The variants of enteral distress syndrome correction with peritonitis. Pirogov Russian Journal of Surgery. 2022;(2):50‑56. (In Russ.)
https://doi.org/10.17116/hirurgia202202150

Подписка 2026 Хирургия. Журнал им. Н.И. Пирогова (Pirogov Russian Journal of Surgery)

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OBJECTIVE

To determine the effectiveness of a new treatment regimen for patients with widespread peritonitis with an accent on enteroprotection based on the use of a drug of the metabolic type of action of remaxol and physiotherapy.

MATERIAL AND METHODS

Clinical and laboratory studies of 82 patients with widespread peritonitis, mainly with grade 2 severity according to the Mannheim peritonitis Index, severe form — according to the ARASNE II scale. In the 1st group (28) patients underwent intraoperative intestinal intubation in the traditional way; in the 2nd (22) — intestinal intubation according to the original method; in the 3rd (32) — intestinal intubation according to the original method and combined use of remaxol (parenterally, enterally and intraperitoneally). An intestinal tube of an original design was used, which allows electrical stimulation of the duodenum in the postoperative period. The study evaluates clinical data, the results of instrumental and laboratory studies: ultrasound examination of the abdominal cavity, assessment of the functional state of the small intestine, a number of indicators of homeostasis.

RESULTS

It was shown that in patients with acute widespread peritonitis who underwent intestinal intubation according to the original method (group 2), as well as in combination with remaxol (group 3), the postoperative period was relatively more favorable. One of the factors optimizing the course of the disease was the relatively rapid restoration of the structural and functional state of the small intestine due to its electrical stimulation. The clinical and laboratory positive effect was especially significant in the 3rd group of patients, in which the use of remaxol, which has a membrane-stabilizing effect, played a special role in the enteroprotective effect. Timely correction of enteral distress syndrome resulted in a significant decrease in the severity of the syndrome of endogenous intoxication and oxidative stress, which was important in significantly improving the results of treatment of patients.

CONCLUSION

The use of technical innovations in the form of an original nasointestinal tube, which allows to quickly restore intestinal motility due to electrical stimulation, as well as the use of remaxol (parenterally, enterally and intraperitoneally) significantly optimize the course of the early postoperative period of patients with acute widespread peritonitis.

Keywords:

peritonitis

enteral distress syndrome

remaxol

electrical stimulation of the intestine

Authors:

Vlasov A.P.

Ogarev Mordovia State University

ORCID: 0000-0003-4731-2952

Salakhov E.K.

Mendeleevsk Central District Hospital

ORCID: 0000-0003-2119-8020

Markin O.V.

Ogarev Mordovia State University

ORCID: 0000-0002-1027-1408

Vlasova T.I.

Ogarev Mordivia State University

ORCID: 0000-0002-2624-6450

Muratova T.A.

Ogarev National Research Mordovia State University

Vilkov A.V.

Ogarev Mordovia State University

ORCID: 0000-0002-7493-109X

Sitdikov I.I.

National Research Mordovian State University N.P. Ogarev of the Ministry of Education and Science Russia

Levkin K.I.

N.P. Ogareva National Research Mordovian State University

Received:

10.09.2021

Accepted:

15.10.2021

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