Quality of life as an efficiency index of surgical treatment of chronic pancreatitis

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Objective — to evaluate quality of life in long-term postoperative period in patients with chronic pancreatitis. Material and methods. There were 31 (21 males and 10 females) patients with complicated forms of chronic pancreatitis who underwent surgery in 2015—2017. Mean age was 49 (44; 53) years, body mass index — 22.4 (20.4; 24) kg/m2. HR-QOL was determined using the questionnaires SF-36, QLQ EORTS C30, VAS. Postoperative control was made no earlier than 6 months after surgery. Median follow-up 11.5 months. The data were analyzed using non-parametric methods. Quantitative data are shown as median with interquartile range. Differences between quantitative values were determined using the Mann—Whitney test. Results. Physical status value (SF-36) before surgery was 30.5 (24.8; 37.5), after surgery — 50.8 (46.7; 56.5). Mental status value was 30.2 (26.7; 36.4) prior to surgery and 53.8 (48.7; 57.3) after operation. Improvement of QoL (QLQ C30) from 29.17 (0; 50.0) before surgery to 75.0 (54.2; 83.3) after operation was observed. VAS-score of pain severity was 8 (8; 10) prior to surgery and 3 (2; 5) after surgery. Differences were significant (p<0.05). Conclusion. Surgical treatment of complicated chronic pancreatitis significantly reduces pain and improves HR-QoL. However, recurrent symptoms of chronic pancreatitis in long-term period cannot be excluded due to short follow-up period (median less than one year). The further investigation is needed.

Keywords:

pancreas

chronic pancreatitis

duodenum-sparing pancreatic head resection

Frey procedure

quality of life

Authors:

Zakharova M.A.

Vishnevsky National Medical Research Center of Surgery, Healthcare Ministry of the Russian Federation Moscow, Russia

Smirnov A.V.

Volgograd State Medical University, Volgograd, Russia

ORCID: 0000-0001-5351-6105

Gorin D.S.

Institut khirurgii im. A.V. Vishnevskogo, Moskva

SPIN RSCI: 4284-4275
Scopus AuthorID: 35299202200
ORCID: 0000-0002-6452-4458

Vorobeva E.A.

Vishnevsky National Medical Research Center for Surgery of the Russia, Moscow, Russia

Kriger A.G.

Institut khirurgii im. A.V. Vishnevskogo, Moskva

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