Imaging of neoangiogenesis of internal carotid artery’s atherosclerotic plaque by contrast-enhanced sonography and histological examination

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Previously, atherosclerosis was considered a disease accompanied exclusively by lipids accumulation. At present time success of fundamental and experimental science confirmed that atherosclerotic process is also associated with neovascularization and prolonged inflammatory response at all stages of atherogenesis from initial manifestations to thrombotic complications. The cause of atherosclerotic plaque instability is neovascularization, which is accompanied by intra-plaque hemorrhage and damage. Complications of carotid arteries atherosclerosis are strokes and transient ischemic attacks. The use of a wide range of diagnostic and pathohistological techniques is required for assessing this pathology. The most promising diagnostic technique is Contrast Enhanced Ultrasonography (CEUS) which allows to assess neovascularization degree in atherosclerotic plaque through the injection of a contrast agents.

Keywords:

neoangiogenesis of internal carotid artery

atherosclerotic plaque

contrast-enhanced sonography

Authors:

Belov Yu.V.

RNTsKh im. akad. B.V. Petrovskogo RAMN

SPIN RSCI: 2740-1439
Scopus AuthorID: 7101862336
ResearcherID: 7101862336
ORCID: 0000-0002-9280-8845

Sinyavin G.V.

Department of Cardiovascular Surgery and Interventional Cardiology, Sechenov First Moscow State Medical University, Moscow, Russia

Bredikhina A.I.

Sechenov First Moscow State Medical University, Medical Faculty, Moscow, Russia

Guseva E.V.

Departament razvitiia meditsinskoĭ pomoshchi detiam i sluzhby rodovspomozheniia Ministerstva zdravookhraneniia i sotsial'nogo razvitiia Rossiĭskoĭ Federatsii, Moskva

Barinov E.V.

Sechenov First Moscow State Medical University, Moscow, Russia

Lukyanova E.A.

Pirogov Russian National Research Medical University, Pediatric Faculty, Moscow, Russia

Luzan P.Yu.

Pirogov Russian National Research Medical University, Pediatric Faculty, Moscow, Russia

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