Early and long-term cognitive disorders after carotid endarterectomy

Belov Yu.V.; Medvedeva L.A.; Zagorulko O.I.; Charchian É.R.; Drakina O.V.

doi:https://doi.org/10.17116/hirurgia20181215

Belov Yu.V.

RNTsKh im. akad. B.V. Petrovskogo RAMN

SPIN RSCI: 2740-1439
Scopus AuthorID: 7101862336
ResearcherID: 7101862336
ORCID: 0000-0002-9280-8845

Medvedeva L.A.

FGBU "RNTsKh im. akad. B.V. Petrovskogo" RAMN

Zagorulko O.I.

Petrovsky Russian Research Center of Surgery

ORCID: 0000-0002-2713-9577

Charchian É.R.

RNTsKh im. akad. B.V. Petrovskogo RAMN

SPIN RSCI: 4641-0523
Scopus AuthorID: 14044681400
ORCID: 0000-0002-0488-2560

Drakina O.V.

Clinic of Aortic and Cardiovascular Surgery of I.M. Sechenov First Moscow State Medical University, Moscow

Early and long-term cognitive disorders after carotid endarterectomy

Authors:

Belov Yu.V., Medvedeva L.A., Zagorulko O.I., Charchian É.R., Drakina O.V.

More about the authors

Journal: Pirogov Russian Journal of Surgery. 2018;(12): 5‑12

DOI: 10.17116/hirurgia20181215

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To cite this article:

Belov YuV, Medvedeva LA, Zagorulko OI, Charchian ÉR, Drakina OV. Early and long-term cognitive disorders after carotid endarterectomy. Pirogov Russian Journal of Surgery. 2018;(12):5‑12. (In Russ.)
https://doi.org/10.17116/hirurgia20181215

Подписка 2026 Хирургия. Журнал им. Н.И. Пирогова (Pirogov Russian Journal of Surgery)

Использование инфографики авторами научных работ

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Abstract:

Aim — to identify correlation of carotid endarterectomy with neurocognitive function and psycho-emotional state changes. Material and methods. There were 120 patients with internal carotid arteries (ICA) stenoses for the period from September 2013 to December 2016. The main group consisted of 100 patients undergoing carotid endarterectomy for internal carotid artery stenosis, control group — 20 patients who refused surgery in 2014—2016. Cognitive function and psycho-emotional state were assessed preoperatively, after 24 hours, 7 days and 3, 6 months postoperatively using the Mini Mental State Examination (MMSE), Frontal assessment battery (FAB), Information—Memory—Concentration Test, Clock Drawing Test and Schulte`s test, Luria Memory Words Test, Hospital Anxiety and Depression Scale (HADS) and Covi Anxiety Scale. Results. Moderate preoperative cognitive impairment was observed in 39 (39%) patients of the main group. De novo postoperative cognitive dysfunction occurred in 65 patients on the 1st day after surgery (65%). Disturbances were noted after 1 week in 26%, after 3 months — in 15%, after 6 months — in 10% of patients. Improved status was noted in 31 (31%) patients of the main group within 1 day after surgery. Improved results were observed after 7 days in 52 (52%) patients, after 3 months — in 67 (67%), after 6 months — in 78 (78%) patients. Mean values of psycho-emotional testing in the main group were high before surgery and significantly decreased on the 1st day after operation. However, advanced anxiety and aggravation of depression occurred in 14% of patients (n=14) that affected cognitive sphere (p<0.01). Progressive cognitive impairment was noted in the control group. Conclusion. Carotid endarterectomy has a positive long-term effect on initially impaired neurocognitive functions (3 and 6 months) (p<0.05). There were no significant differences in cognitive testing data in subgroups of eversion and classical procedures (p>0.05). Early postoperative depressive disorders significantly increase the risk of postoperative cognitive dysfunction.

Keywords:

carotid endarterectomy

stenosis of internal carotid arteries

neurocognitive disorders

postoperative cognitive dysfunction

psychoemotional disorders

neurocognitive testing

neuropsychological testing

Authors:

Belov Yu.V.

RNTsKh im. akad. B.V. Petrovskogo RAMN

SPIN RSCI: 2740-1439
Scopus AuthorID: 7101862336
ResearcherID: 7101862336
ORCID: 0000-0002-9280-8845

Medvedeva L.A.

FGBU "RNTsKh im. akad. B.V. Petrovskogo" RAMN

Zagorulko O.I.

Petrovsky Russian Research Center of Surgery

ORCID: 0000-0002-2713-9577

Charchian É.R.

RNTsKh im. akad. B.V. Petrovskogo RAMN

SPIN RSCI: 4641-0523
Scopus AuthorID: 14044681400
ORCID: 0000-0002-0488-2560

Drakina O.V.

Clinic of Aortic and Cardiovascular Surgery of I.M. Sechenov First Moscow State Medical University, Moscow

Close metadata

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