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Sazhin A.V.

Pirogov Russian National Research Medical University

Nechay T.V.

Department of general surgery and radiology, Russian National Research Medical University named after N.I. Pirogov, Moscow

Titkova S.M.

Pirogov Russian National Research Medical University of Healthcare Ministry of the Russian Federation, Moscow, Russia

Anurov M.V.

Pirogov Russian National Research Medical University of Healthcare Ministry of the Russian Federation, Moscow, Russia

Tyagunov A.E.

Department of general surgery and radiology, Russian National Research Medical University named after N.I. Pirogov, Moscow

Balakirev Yu.S.

Pirogov Russian National Research Medical University, Moscow, Russia;
City Clinical Hospital №1 of Moscow Healthcare Department, Moscow, Russia

Ermakov I.V.

Pirogov Russian National Research Medical University, Moscow, Russia;
City Clinical Hospital №29 of Moscow Healthcare Department, Moscow, Russia

Tyagunov A.A.

Pirogov Russian National Research Medical University of Healthcare Ministry of the Russian Federation, Moscow, Russia

Melnikov-Makarchuk K.Yu.

Pirogov Russian National Research Medical University, Moscow, Russia;
City Clinical Hospital №29 of Moscow Healthcare Department, Moscow, Russia

Glagolev N.S.

Pirogov Russian National Research Medical University of Healthcare Ministry of the Russian Federation, Moscow, Russia;
Bauman Municipal Clinical Hospital №29 of Moscow Healthcare Department, Moscow, Russia

Mirzoian A.T.

Rossiĭskiĭ gosudarstvennyĭ meditsinskiĭ universitet, Moskva

Kurashinova L.S.

Pirogov Russian National Research Medical University of Healthcare Ministry of the Russian Federation, Moscow, Russia

Kolygin A.V.

Department of general surgery and radiology Russian National Research Medical University named after N.I. Pirogov, School of Pediatry, Moscow

Nechai V.S.

Tula Regional Clinical Hospital, Tula, Russia

Ivanova E.A.

Pirogov Russian National Research Medical University, Moscow, Russia

Ivakhov G.B.

Pirogov Russian National Research Medical University & ,V.S. Savel’ev University Faculty Clinic, Moscow, Russia

Mosin S.V.

Rossiĭskiĭ gosudarstvennyĭ meditsinskiĭ universitet, Moskva

Fast-track rehabilitation for acute cholecystitis: intermediate outcomes of prospective randomized trial

Authors:

Sazhin A.V., Nechay T.V., Titkova S.M., Anurov M.V., Tyagunov A.E., Balakirev Yu.S., Ermakov I.V., Tyagunov A.A., Melnikov-Makarchuk K.Yu., Glagolev N.S., Mirzoian A.T., Kurashinova L.S., Kolygin A.V., Nechai V.S., Ivanova E.A., Ivakhov G.B., Mosin S.V.

More about the authors

Journal: Pirogov Russian Journal of Surgery. 2018;(12): 13‑20

DOI: 10.17116/hirurgia201812113

Views: 1769

Downloaded: 40

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To cite this article:

Sazhin AV, Nechay TV, Titkova SM, et al. . Fast-track rehabilitation for acute cholecystitis: intermediate outcomes of prospective randomized trial. Pirogov Russian Journal of Surgery. 2018;(12):13‑20. (In Russ.)
https://doi.org/10.17116/hirurgia201812113

Подписка 2025 (Pirogov Russian Journal of Surgery)
МСФ на ЯМ
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Aim — to analyze an efficacy of FT-protocol in patients with acute cholecystitis. Material and methods. Prospective randomized study included 102 patients (45 of main group (FT) and 57 of control groups). Patients did not differ by TG13 severity index. The protocol included information, antibiotic prophylaxis, restriction of drainage, intraperitoneal anesthesia with long-term anesthetics, low pressure pneumoperitoneum, antiemetics in the presence of risk factors, early activation and feeding of the patient. Pain was assessed by VAS immediately after surgery, and 2, 6 and 12—24 hours postoperatively. Results. Surgery time was similar in both groups. Need for anesthesia and pain severity were significantly lower in the FT group. A total absence of pain (VAS 0—1) on the 1st postoperative day was noted in 8 (17.7%) of the FT group and 2 (3.5%) patients of the control group (p=0.038). Shoulder pain developed in 4 (8.9%) cases of the main and 22 (38.6%) cases of the control group (p=0.001). Postoperative nausea developed in 13% of the FT group vs 40.5% in the control group (p=0.05). Hospital-stay was 1.29±0.7 days and 2.7±1.6 (p<0.0001), respectively. The time of the first stool was similar. Twenty-four (53.5%) patients of the FT group and 8,9% of the control group were discharged on 1st postoperative day. There were 2 (IIIA) complications in the main group and 3 — in the control group (IIIA, IIIB and IV). There were no mortality and readmissions. Conclusion. FT protocol in AC reduce postoperative pain, dyspepsia, shoulder pain and in-hospital stay with equal number of postoperative complications.

Keywords:

acute cholecystitis
prospective randomized trial

Authors:

Sazhin A.V.

Pirogov Russian National Research Medical University

Nechay T.V.

Department of general surgery and radiology, Russian National Research Medical University named after N.I. Pirogov, Moscow

Titkova S.M.

Pirogov Russian National Research Medical University of Healthcare Ministry of the Russian Federation, Moscow, Russia

Anurov M.V.

Pirogov Russian National Research Medical University of Healthcare Ministry of the Russian Federation, Moscow, Russia

Tyagunov A.E.

Department of general surgery and radiology, Russian National Research Medical University named after N.I. Pirogov, Moscow

Balakirev Yu.S.

Pirogov Russian National Research Medical University, Moscow, Russia;
City Clinical Hospital №1 of Moscow Healthcare Department, Moscow, Russia

Ermakov I.V.

Pirogov Russian National Research Medical University, Moscow, Russia;
City Clinical Hospital №29 of Moscow Healthcare Department, Moscow, Russia

Tyagunov A.A.

Pirogov Russian National Research Medical University of Healthcare Ministry of the Russian Federation, Moscow, Russia

Melnikov-Makarchuk K.Yu.

Pirogov Russian National Research Medical University, Moscow, Russia;
City Clinical Hospital №29 of Moscow Healthcare Department, Moscow, Russia

Glagolev N.S.

Pirogov Russian National Research Medical University of Healthcare Ministry of the Russian Federation, Moscow, Russia;
Bauman Municipal Clinical Hospital №29 of Moscow Healthcare Department, Moscow, Russia

Mirzoian A.T.

Rossiĭskiĭ gosudarstvennyĭ meditsinskiĭ universitet, Moskva

Kurashinova L.S.

Pirogov Russian National Research Medical University of Healthcare Ministry of the Russian Federation, Moscow, Russia

Kolygin A.V.

Department of general surgery and radiology Russian National Research Medical University named after N.I. Pirogov, School of Pediatry, Moscow

Nechai V.S.

Tula Regional Clinical Hospital, Tula, Russia

Ivanova E.A.

Pirogov Russian National Research Medical University, Moscow, Russia

Ivakhov G.B.

Pirogov Russian National Research Medical University & ,V.S. Savel’ev University Faculty Clinic, Moscow, Russia

Mosin S.V.

Rossiĭskiĭ gosudarstvennyĭ meditsinskiĭ universitet, Moskva

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