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Dobrodeev A.Yu.

Tomsk Research Oncology Institute

Zav’yalov A.A.

Research and Practical Centre for Clinical Investigations and Evaluation of Medical Technologies, Moscow Health Department, Moscow, Russia

Tuzikov S.A.

Tomsk Research Oncology Institute;
Siberian State Medical University, Health Ministry of the Russian Federation, Tomsk

Results of surgical and combined treatment of non-small cell lung cancer

Authors:

Dobrodeev A.Yu., Zav’yalov A.A., Tuzikov S.A.

More about the authors

Journal: Pirogov Russian Journal of Surgery. 2016;(3): 26‑31

DOI: 10.17116/hirurgia2016326-31

Read: 793 times

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Table of contents

RESULTS OF SURGICAL AND COMBINED TREATMENT OF NON-SMALL CELL LUNG CANCER
RESULTS OF SURGICAL AND COMBINED TREATMENT OF NON-SMALL CELL LUNG CANCER

To cite this article:

Dobrodeev AYu, Zav’yalov AA, Tuzikov SA. Results of surgical and combined treatment of non-small cell lung cancer. Pirogov Russian Journal of Surgery. 2016;(3):26‑31. (In Russ.)
https://doi.org/10.17116/hirurgia2016326-31

Подписка 2026 Хирургия. Журнал им. Н.И. Пирогова (Pirogov Russian Journal of Surgery)
МСФ на ЯМ
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Abstract:

Aim. To study the results of surgical and combined treatment of non-small cell lung cancer stage III using preoperative chemotherapy and intraoperative radiotherapy. Material and methods. The study included 152 patients with non-small cell lung cancer stage III. Overall and recurrence-free 5-year survival were 20.4% and 14.3% respectively. These values were significantly higher in case of combined treatment consisting of radical surgery and intraoperative radiotherapy (29.2% and 18.7% respectively, p<0.05). Results. The best results were obtained in case of preoperative chemotherapy with paclitaxel/carboplatin, radical surgery and intraoperative radiotherapy on background of radiosensitization with cisplatin. Overall and recurrence-free 5-year survival were 47.9% and 41.7% respectively (p<0.05). Incidence of postoperative complications and mortality rate did not significantly differ between surgical and combined treatment (p>0.05).

Keywords:

lung cancer
surgical treatment
combined treatment
preoperative chemotherapy
intraoperative radiotherapy
survival

Authors:

Dobrodeev A.Yu.

Tomsk Research Oncology Institute

Zav’yalov A.A.

Research and Practical Centre for Clinical Investigations and Evaluation of Medical Technologies, Moscow Health Department, Moscow, Russia

Tuzikov S.A.

Tomsk Research Oncology Institute;
Siberian State Medical University, Health Ministry of the Russian Federation, Tomsk

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References:

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