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A.Yu. Dobrodeev

Tomsk Research Oncology Institute

A.A. Zav’yalov

Research and Practical Centre for Clinical Investigations and Evaluation of Medical Technologies, Moscow Health Department, Moscow, Russia

S.A. Tuzikov

Tomsk Research Oncology Institute;
Siberian State Medical University, Health Ministry of the Russian Federation, Tomsk

Results of surgical and combined treatment of non-small cell lung cancer

Authors:

A.Yu. Dobrodeev, A.A. Zav’yalov, S.A. Tuzikov

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Journal: Pirogov Russian Journal of Surgery. 2016;(3): 26‑31

DOI: 10.17116/hirurgia2016326-31

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Table of contents

RESULTS OF SURGICAL AND COMBINED TREATMENT OF NON-SMALL CELL LUNG CANCER
RESULTS OF SURGICAL AND COMBINED TREATMENT OF NON-SMALL CELL LUNG CANCER

To cite this article:

Dobrodeev AYu, Zav’yalov AA, Tuzikov SA. Results of surgical and combined treatment of non-small cell lung cancer. Pirogov Russian Journal of Surgery. 2016;(3):26‑31. (In Russ.)
https://doi.org/10.17116/hirurgia2016326-31

Подписка 2026 Хирургия. Журнал им. Н.И. Пирогова (Pirogov Russian Journal of Surgery)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

Aim. To study the results of surgical and combined treatment of non-small cell lung cancer stage III using preoperative chemotherapy and intraoperative radiotherapy. Material and methods. The study included 152 patients with non-small cell lung cancer stage III. Overall and recurrence-free 5-year survival were 20.4% and 14.3% respectively. These values were significantly higher in case of combined treatment consisting of radical surgery and intraoperative radiotherapy (29.2% and 18.7% respectively, p<0.05). Results. The best results were obtained in case of preoperative chemotherapy with paclitaxel/carboplatin, radical surgery and intraoperative radiotherapy on background of radiosensitization with cisplatin. Overall and recurrence-free 5-year survival were 47.9% and 41.7% respectively (p<0.05). Incidence of postoperative complications and mortality rate did not significantly differ between surgical and combined treatment (p>0.05).

Keywords:

lung cancer
surgical treatment
combined treatment
preoperative chemotherapy
intraoperative radiotherapy
survival

Authors:

A.Yu. Dobrodeev

Tomsk Research Oncology Institute

A.A. Zav’yalov

Research and Practical Centre for Clinical Investigations and Evaluation of Medical Technologies, Moscow Health Department, Moscow, Russia

S.A. Tuzikov

Tomsk Research Oncology Institute;
Siberian State Medical University, Health Ministry of the Russian Federation, Tomsk

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References:

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