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Chepurnenko S.A.

Rostov State Medical University, Rostov-on-Don, Russia;
Rostov Regional Clinical Hospital, Rostov-on-Don, Russia

Shavkuta G.V.

Rostov State Medical University, Rostov-on-Don, Russia

Nasytko A.D.

Rostov State Medical University, Rostov-on-Don, Russia

Mitral regurgitation due to papillary-chordal dysfunction, the possibility of drug therapy

Authors:

Chepurnenko S.A., Shavkuta G.V., Nasytko A.D.

More about the authors

Journal: Russian Journal of Cardiology and Cardiovascular Surgery. 2018;11(6): 66‑70

DOI: 10.17116/kardio20181106166

Views: 4378

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Table of contents

MITRAL REGURGITATION DUE TO PAPILLARY-CHORDAL DYSFUNCTION, THE POSSIBILITY OF DRUG THERAPY
MITRAL REGURGITATION DUE TO PAPILLARY-CHORDAL DYSFUNCTION, THE POSSIBILITY OF DRUG THERAPY

To cite this article:

Chepurnenko SA, Shavkuta GV, Nasytko AD. Mitral regurgitation due to papillary-chordal dysfunction, the possibility of drug therapy. Russian Journal of Cardiology and Cardiovascular Surgery. 2018;11(6):66‑70. (In Russ.)
https://doi.org/10.17116/kardio20181106166

Подписка 2025-2 (Russian Journal of Cardiology and Cardiovascular Surgery)
 
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Abstract It is presented clinical case of severe mitral insufficiency in 63-years-old woman with subacute myocarditis. Because of emergence of the new class of angiotensin receptors and neprilizin inhibitors in Russia, ramipril was replaced with valsartan/sacubitryl. Reduced left ventricular volume and severity of mitral regurgitation due to papillary-chordal dysfunction were observed.

Keywords:

mitral regurgitation
papillary-chordal dysfunction
sacubitryl/valsartan
chronic heart failure

Authors:

Chepurnenko S.A.

Rostov State Medical University, Rostov-on-Don, Russia;
Rostov Regional Clinical Hospital, Rostov-on-Don, Russia

Shavkuta G.V.

Rostov State Medical University, Rostov-on-Don, Russia

Nasytko A.D.

Rostov State Medical University, Rostov-on-Don, Russia

List of references:

  1. Votta E, et al. 3-D computational analysis of the stress distribution on the eaflets after edge-to-edge repair of mitral regurgitation. Edge-to-edge repair-induced stresses. 2014;9312-096.
  2. Lopina NA, et al. Clinical case of acute chord rupture of the mitral valve posterior leaflet in older patient with comorbidities. 2015;1(3):2313-8956. (In Russ.)
  3. Bokeria OL. Sudden cardiac death and defects of the mitral and aortic valves. Annals of arrhythmology. 2013;10(3):162-170. (In Russ.)
  4. Enriques-Sarano M, et al. Quantitative determinants of the outcome of asymptomaticmitral regurgitation. N Engl J Med. 2005;352:875-883.
  5. Rybakova MK, et al. Echocardiography from M.K. Fisherman’s. M.: Publishing house «Vidar». 2016;600. (In Russ.)
  6. Alain Cohen-Solal, et al. Guidelines for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC). Eur Heart J. 2016;37(27):2129-2120.
  7. Scott D. Solomon et al. Influence of ejection fraction on outcomes and efficacy of sacubitril/valsartan (LCZ696) in heart failure with reduced ejection fraction. 2016;9:e002744. https://doi.org/10.1161/CIRCHEARTFAILURE.115.002744
  8. Feldman AM. Valsartan/Sacubitril for heart failure reconciling disparities between preclinical and clinical investigations. 2016;315(1):25-26. https://doi.org/10.1001/jama.2015.17632
  9. Stolov SV, et al. The results of the use of systemic enzyme therapy in the complex treatment of coronary atherosclerosis. The attending physician. 2013;6(13). (In Russ.)
  10. Solomon SD, et al. Influence of ejection fraction on outcomes and efficacy of Sacubitril/Valsartan (LCZ696) in heart failure with reduced ejection fraction. 2016;9:e002744. https://doi.org/10.1161/CIRCHEARTFAILURE.115.002744
  11. Claggett B, et al. Estimating the long-term treatment benefits of Sacubitril–Valsartan. 2015;373:2289-2290. https://doi.org/10.1056/NEJMc1509753
  12. Trueman D, et al. The cost-effectiveness of Sacubitril/Valsartan for the treatment of chronic heart failure with reduced ejection fraction in England and Scotland: applying real-world evidence to enhance generalisability to A UK population. 2016;19(7):A655. https://doi.org/10.1016/j.jval.2016.09.1772

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