Aim — to compare cognitive function state in stable coronary artery disease patients depending on myocardial revascularization mode. Material and methods. There were 352 patients with coronary artery disease aged 57.6±7.7 years who underwent CABG or PCI. Inclusion criterion was indicated myocardial revascularization, exclusion criteria — severe heart valve dysfunction due to CAD, left ventricular aneurysm, acute myocardial infarction, severe left ventricular systolic dysfunction (LVEF <35), significant ICA stenosis, age over 80 years, preoperative acute neurologic disease. Three groups were applied: group I included patients after on-pump CABG (n=107), group II — off-pump CABG (n=76), group III — PCI (n=169) with drug-eluting stents deployment. Mean follow-up was 37.9±6 months. Results. Impaired CF was observed after CABG both with cardiopulmonary bypass and off-pump. At the same time, 3-month CF recovery was registered only in group II. In on-pump CABG group restored CF was observed only after 6 months. There was no CF impairment after PCI. Following predictors of impaired CF were determined: age over 60 years (p=0.042), concomitant diabetes (glycated hemoglobin >7.5% (p=0.026), glycated hemoglobin 6.5—7.5% (p=0.033), smoking (p=0.045), ICA stenosis less than 70% (p=0.047) and Charlson comorbidity index over 5 (p=0.031). Myocardial revascularization with CPB (p=0.038) and off-pump (p=0.041) was a prognostic criterion for CF violation. Conclusion. CABG is associated with postoperative cognitive dysfunction, but CF recovery is faster after off-pump procedure. Endovascular interventions had no effect on the state of CF.