Aim - to investigate the impact of previous PCI on the results of subsequent coronary bypass grafting (CABG). Material and methods. 158 patients after previous PCI underwent isolated CABG for the period from 2009 to 2015. These patients formed group 1 and were divided into two subgroups. Subgroup 1a included patients with single PCI and subgroup 1b was generated by repeated PCI patients. Group 2 included 160 patients without previous PCI who had undergone CABG at the same time that the first group of patients. Preoperative clinical and morphological parameters, as well as early and long-term outcomes of CABG were assessed. Results. Myocardial infarction was more common in patients with previous PCI (subgroup 1a - 65%, subgroup 1b - 72%, group 2 - 43%). Preoperative angiography analysis detected higher frequency of diffuse coronary disease in group 1 (47 and 59% in subgroups 1a and 1b respectively, 32% in control group). The period of myocardial ischemia and cardiopulmonary bypass time were higher in subgroup 1b. The need for cardiac support was in 2 times higher in the first group compared with control group (p=0.01). 1-year outcomes assessment identified more often re-hospitalizations in repeated PCI subgroup (18% vs. 3% and 2% in 1a and 2 groups respectively). Three years follow up had demonstrated more often recurrent angina (26% vs 10%; p=0,001), re-hospitalizations (33% vs 15%; p=0,001), reinterventions (19% vs 5%; p=0,001) and medical therapy correction (15% vs 6%; p=0,001) in patients of group 1. Conclusion. Previous PCI is negative prognostic factor for CABG procedure, especially in repeated PCI patients.