The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-4329
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2026
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Saiutina E.V.

OOO Klinika innovatsionnoĭ khirurgii, Klin

Sedov A.V.

OOO Klinika innovatsionnoĭ khirurgii, Klin

Kalitko I.M.

OOO Klinika innovatsionnoĭ khirurgii, Klin

Efficacy and safety of enoxaparin sodium in femoro-distal vascular reconstructions

Authors:

Saiutina E.V., Sedov A.V., Kalitko I.M.

More about the authors

Journal: Russian Journal of Cardiology and Cardiovascular Surgery. 2012;5(6): 39‑43

Read: 3293 times

Download PDF (RU)
Contact the author
Table of contents

EFFICACY AND SAFETY OF ENOXAPARIN SODIUM IN FEMORO-DISTAL VASCULAR RECONSTRUCTIONS
EFFICACY AND SAFETY OF ENOXAPARIN SODIUM IN FEMORO-DISTAL VASCULAR RECONSTRUCTIONS

To cite this article:

Saiutina EV, Sedov AV, Kalitko IM. Efficacy and safety of enoxaparin sodium in femoro-distal vascular reconstructions. Russian Journal of Cardiology and Cardiovascular Surgery. 2012;5(6):39‑43. (In Russ.)

Подписка 2026 Кардиология и сердечно-сосудистая хирургия (Russian Journal of Cardiology and Cardiovascular Surgery)
МСФ на ЯМ
Использование инфографики авторами научных работ
Close metadata
Recommended articles:
Pharmacological treatment and prevention of ischemia-reperfusion syndrome in percutaneous coro­nary inte­rvention. Russian Journal of Cardiology and Cardiovascular Surgery. 2025;(2):191-200
Vita­min D role in oral cavity diseases. Stomatology. 2025;(1):81-86
Improving the para­medic and obstetric centers heads labour responsibilities in the field of preventive measures realisation. Russian Journal of Preventive Medi­cine. 2025;(3):14-19
Review and reso­lution of the Council of Expe­rts on the topic «The role of the combination of unde­natured type II collagen UC-II, vita­min C, and trace elements in reco­vering and maintaining the function of the musculoskeletal system, and preservation of health of the joints». Russian Journal of Preventive Medi­cine. 2025;(4):102-110
The expe­rience of the narcological service medi­cal specialists in the prevention of substance use among adolescents and youth. Russian Journal of Preventive Medi­cine. 2025;(5):62-68
Current approaches to the prevention and treatment of post-thrombotic syndrome. Russian Journal of Preventive Medi­cine. 2025;(5):111-116
Comparative analysis of preventive action of drinking sulfate mine­ral water on neurohormonal and immune regu­lation organs in radiation expo­sure to rats. Problems of Balneology, Physiotherapy and Exercise Therapy. 2025;(2):45-51
Possibilities for opti­mizing preventive and therapeutic dental care for the pediatric popu­lation of Chapayevsk using SWOT analysis. Russian Journal of Stomatology. 2025;(2):39-44
Rapi­dly progressive periodontitis. (A successful expe­rience of eighteen years of obse­rvation). Russian Journal of Stomatology. 2025;(2):61-67
Contribution of the Russian Academy of Sciences Academician R.G. Oganov to the deve­lopment of the dome­stic preventive cardiology. Russian Journal of Preventive Medi­cine. 2025;(6):7-10
Abstract:

Experience of enoxaparin sodium (Gemapaxane, Italfarmaco, S.p.A., Italy) application in 25 patients with peripheral artery disease at distal vascular reconstructions is presented. It is shown that Gemapaxane is characterized by efficacy, good tolerance and high profile of safety and can be recommended for patients with very high cardiovascular risk for application in intra- and postoperative period after vascular reconstruction.

Keywords:

vascular reconstructive surgery
thrombotic complications
prophylaxis
enoxaparin sodium
Gemapaxane

Authors:

Saiutina E.V.

OOO Klinika innovatsionnoĭ khirurgii, Klin

Sedov A.V.

OOO Klinika innovatsionnoĭ khirurgii, Klin

Kalitko I.M.

OOO Klinika innovatsionnoĭ khirurgii, Klin

Close metadata

References:

  1. Belov Yu.V., Stepanenko A.B., Gene A.P. i dr. Khirurgicheskoe lechenie bol'nykh s mnozhestvennym porazheniem arterii nizhnikh konechnostei. Angiol i sosud khir 2002; 1: 72-79.
  2. Belousov D. Yu. Bioanalogi - naskol'ko oni podobny? Sait Rossiiskogo obshchestva klinicheskikh issledovatelei, Moskva. Dostupno na: http://cra-club.ru/content/view/414/11/.
  3. Gaibov A.D., Mirzoev S.A. Rannie posleoperatsionnye oslozhneniya pri rekonstruktivnykh operatsiyakh na sosudakh. Byull NTsSSKh im. A.N. Bakuleva 2003; 4: 132.
  4. Gontarenko V.N. Ispol'zovanie nizkomolekulyarnykh geparinov v rekonstruktivnoi sosudistoi khirurgii: Avtoref. dis. … kand. med. nauk. M 2006; 159.
  5. Gontarenko V.N., Sapelkin S.V., Titova M.I., Marynich A.A. Profilaktika tromboticheskikh oslozhnenii v rekonstruktivnoi sosudistoi khirurgii s ispol'zovaniem nizkomolekulyarnykh geparinov. Vestn MNKhTs 2008; 2: 102-105.
  6. Kazanchan P.O., Debelyi Yu.V., Kevlishvili Z.U. Otdalennye rezul'taty bedrenno-tibial'nykh rekonstruktsii. Khirurgiya 2004; 11: 8-14.
  7. Karasev A.Yu. Profilaktika trombozov pri rekonstruktivnykh operatsiyakh u bol'nykh obliteriruyushchim aterosklerozom arterii nizhnikh konechnostei: Avtoref. dis. … kand. med. nauk. M 2004; 130.
  8. Kirienko A.I., Leont'ev S.G., Lebedev I.S., Seliverstov E.I. Trombozy i tromboembolii. Profilaktika venoznykh tromboembolicheskikh oslozhnenii v khirurgicheskoi ppaktike. Consilium Medicum 2006; 8: 7.
  9. Kuz'min V.V., Tsaregorodtseva H.A., Yurchenko N.H. Profilaktika aterotromboticheskikh i tromboembolicheskikh oslozhnenii v posleoperatsionnom periode pri ateroskleroticheskoi gangrene. Khirurgiya. Prilozhenie k zhurnalu Consilium Medicum 2006; 8: 2.
  10. Melkumyan A.L. Patogeneticheskoe obosnovanie ispol'zovaniya fraksiparina v rekonstruktivnoi sosudistoi khirurgii: Avtoref. dis. … kand. med. nauk. M 2000; 126.
  11. Natsional'nye rekomendatsii po vedeniyu patsientov s sosudistoi arterial'noi patologiei (Rossiiskii sogla- sitel'nyi dokument). Chast' 1. Perifericheskie arterii. M: Izd-vo NTsSSKh im. A. N. Bakuleva RAMN 2010; 176.
  12. Panchenko E.P. Kontseptsiya aterotromboza osnova patogeneza serdechno-sosudistykh zabolevanii. Osnovnye napravleniya antitromboticheskoi terapii. Rus med zhurn 2005; 7: 433-440.
  13. Pokrovskii A.B. Nizkomolekulyarnye gepariny v rekonstruktivnoi sosudistoi khirurgii. Vserossiiskaya nauchnaya konferentsiya "Klinicheskaya gemostaziologiya i gemoreologiya v serdechno-sosudistoi khirurgii", 1-ya: Materialy. M 2003; 55-70.
  14. Pokrovskii A.B., Sapelkin C.B., Nesuk O.M., Sklyarova E.A. Rol' nizkomolekulyarnykh geparinov (kleksan) v profilaktike koronarnykh oslozhnenii v rekonstruktivnoi sosudistoi khirurgii. Angiol i sosud khir 1999; 4: 104-108.
  15. Proizvoditeli dzhenerikov delayut stavku na biosimilyary. Remedium 2011; 3: 17-18.
  16. Rossiiskie klinicheskie rekomendatsii po diagnostike, lecheniyu i profilaktike venoznykh tromboembolicheskikh oslozhnenii. Flebologiya 2010; 4: 1-37.
  17. Soglasitel'nyi dokument ekspertov pod rukovodstvom akademika RAN i RAMN V.S. Savel'eva. M 2000.
  18. Sturov V G. Opyt klinicheskogo primeneniya preparata "Gemapaksan" (enoksaparin natriya) v akushersko-ginekologicheskoi klinike. Trudnyi patsient 2011; 8-9: 4-9.
  19. Yavelov I.Ya. Primenenie enoksaparina pri serdechno-sosudistykh zabolevaniyakh: kak sdelat' lechenie naibolee effektivnym i bezopasnym. Kardiovask ter i prof 2011; 10: 6.
  20. Becker R.C., Fintel D.J., Green D. Antithrombotic therapy. 3rd ed. Professional Communications 2004; 36-40.
  21. Gori A.M., Pepe G., Attanasio M. et al. Tissue factor reduction and tissue factor pathway inhibitor release after heparinadministration. Thromb Haemost 1999; 81: 589-593.
  22. Gottlieb A., Tabares A.H., Levy P. et al. Use of Low Molecular Weight Heparin in Patients with Heparin-induced Thrombocytopenia Undergoing Carotid Endarterectomy. Anesthesiology 1996; 85 (3): 678-681.
  23. Hochart Y., Jenkins P.V., Smith O.P., White B. Low molecularweight heparin and unfractionated heparins induce a downregulation of inflammation: decreased levels of proinflammatory cytokines and nuclear factorkappaB in LPSstimulated human leucocytes. Br J Haematol 2006; 133 (1): 62-67.
  24. Kroneman H., Eikelboom B.C., Knot E.A. et al. Pharmacokinetics of low-molecular-weight heparin and unfractionated heparin during elective aortobifemoral bypass grafting. J Vasc Surg 1991; 14 (2): 208-214.
  25. Murray G. Heparin in surgical treatment of blood vessels. Arch Surg 1940; 40: 307.
  26. Melissari E., Stringer M.D., Kakkar V.V. The effect of a bolus injection of unfractionated or low molecular weight heparin during aortobifemoral bypass grafting. Eur J Vasc Surg 1989; 3 (2): 121-126.
  27. Norgren L. Swedish EnoxaVasc Study Group. Can low molecular weight heparin replace unfractionated heparin during peripheral arterial reconstruction? An open label prospective randomized controlled trial. J Vasc Surg 2004; 39 (5): 977-984.
  28. Samama C.M., Barre E., Combe S. et al. A pilot study on the use of a low molecular weight heparin (Enoxaparin) in arterial reconstructive surgery. Semin Thromb Hemost 1991; 17 (4): 367-370.
  29. Samama C.M., Gigou F., Ill P. Low-molecular-weight heparin vs. unfractionated heparin in femorodistal reconstructive surgery: a multicenter open randomized study. Enoxart Study Group. Ann Vasc Surg 1995; 9 Suppl: 45-53.
  30. Samama C.M., Mouren S., Bridel M.P. et al. Peri- and postoperative use of low molecular weight heparin in peripheral vascular surgery. Ann Fr Anesth Reanim 1990; 9 (2): 102-105.
  31. Samama C.M., Thiry D., Elalamy I. et al. Perioperative activation of hemostasis in vascular surgery patients. Anesthesiology 2001; 94 (1): 74-78.
  32. Swedenborg J., Nydahl S., Egberg N. Related Articles, Low molecular mass heparin instead of unfractionated heparin during infrainguinal bypass surgery. Eur J Vasc Endovasc Surg 1996; 11 (1): 59-64.
  33. Wells J., Nicosia S., Wale C. et al. Thrombin generation in patients undergoing carotid endarterectomy: implications in acute vessel wall closure and antithrombotic therapy. Thromb Res 1994; 75 (4): 419-426.
  34. Wilson N.V., Melissari E., Standfield N.J., Kakkar V.V. Intra-operative antithrombotic therapy with low molecular weight heparin in aortic surgery: How should heparin be administered? Eur J Vasc Surg 1991; 5: 565-569.
Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.