107 patients undergoing carotid artery stenting during 2009-2011 years with application of devices for distal protection from embolism were included in the study. 33 patients with bilateral carotid lesions formed the 1 group, 74 patients with unilateral carotid lesions formed the 2 group. Coronary heart disease of III-IV functional class and III NYHA class chronic heart failure were observed more often in the 2 group (p=0.01). In the 1 group 8 (24.2%) patients underwent one-stage treatment, 15 (42.4%) - two-stage treatment, 10 (30.3%) - three-stage treatment. In the 2 group 54 (73%) patients underwent one-stage treatment, 20 (27%) - two-stage treatment. Carotid revascularization as the first stage of treatment including single-step operations on carotid and coronary arteries was required in 29 (87.8%) patients from the 1 group and in 62 (83.2%) patients from the 2 group. Carotid stenting was combined with myocardial revascularization in 27 (82%) patients from the 1 group. Coronary artery bypass grafting under artificial circulation was carried out in 13 (39.4%) patients. Percutaneous coronary angioplasty (PCA) with stenting was applied in 14 (42.4%) patients; among them in 9 (27.3%) cases PCA was combined with carotid stenting. In the 2 group carotid stenting was combined with myocardial revascularization in 51 (69%) patients. 10 (13.5%) patients underwent coronary artery bypass grafting, 41 (55.4%) - PCA; among them PCA was combined with carotid stenting in 31 (42%) patients. During 30 das after the last stage lethal outcomes and myocardial infarctions were not observed. Minor stroke was observed in 3 patients: in 1 from the first group and in 2 from the second group. Total frequency of complications during 30 days amounted 2.8%. It is drawn a conclusion that carotid stenting in patients with combined coronary and carotid lesions is accompanied by small amount of complications. Despite the fact that angina and chronic heart failure of higher functional classes with lesser left ventricular ejection fraction are observed more often in patients with bilateral carotid lesions carotid stenting among them is not accompanied by higher risk for cardiac and cerebral vascular complications.