Modern view on the problem of atherosclerosis in HIV-positive people

Alieva A.M.; Sozykin A.V.; Lyalina V.V.; Skripnichenko E.A.; Teplova N.V.; Batov M.A.; Nikitin A.E.; Shnakhova L.M.; Izimarieva D.V.; Nikitin I.G.

doi:https://doi.org/10.17116/Cardiobulletin20221702125

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Abstract:

HIV-associated diseases are quite diverse, and cardiovascular lesions are one of the direct causes of mortality in HIV patients. Observational studies have shown that HIV-infected individuals have a high risk of adverse cardiovascular events compared to other ones. Cardiovascular diseases caused by atherosclerosis, including myocardial infarction and stroke, are currently one of the main causes of mortality in these patients. Some authors empathized acceleration of atherogenesis following HIV infection. Possible causes are direct impact of HIV and other factors occurring in these people: side effects of antiretroviral therapy, drug abuse, HIV-related comorbidities. In addition to specific risk factors, patients with HIV infection can also have traditional ones including smoking, physical inactivity, obesity and hypercholesterolemia. The results of various studies show a huge scientific and practical interest in the problem of atherosclerosis in patients with HIV infection.

Keywords:

HIV

cardiovascular diseases

atherosclerosis

endothelial dysfunction

statins

Authors:

Alieva A.M.

Pirogov Russian National Research Medical University

Sozykin A.V.

Pirogov Russian National Research Medical University;
Central Clinical Hospital of the Russian Academy of Science

ORCID: 0000-0002-2570-5758

Lyalina V.V.

Pirogov Russian National Research Medical University

Skripnichenko E.A.

Pirogov Russian National Research Medical University

Teplova N.V.

Pirogov Russian National Research Medical University

SPIN RSCI: 9056-1948
Scopus AuthorID: 6603037947
ORCID: 0000-0003-4259-0945

Batov M.A.

National Medical Research Radiological Centre

Nikitin A.E.

Central Clinical Hospital of the Russian Academy of Science

Shnakhova L.M.

Sechenov First Moscow State Medical University

Izimarieva D.V.

Central Clinical Hospital of the Russian Academy of Science

Nikitin I.G.

Pirogov Russian National Research Medical University

Received:

26.03.2022

Accepted:

11.04.2022

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References:

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