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Lobastov K.V.

Pirogov Russian National Research Medical University

Kaplina (Demekhova) M.Yu.

Pavlov First Saint Petersburg State Medical University

Kononova Yu.A.

Central Polyclinic No. 1 of the Ministry of Internal Affairs of Russia

Kozlova V.V.

Pirogov Russian National Research Medical University

Schastlivtsev I.V.

Pirogov Russian National Research Medical University

Phlebolymphedema: Modern Views and Methods of Correction

Authors:

Lobastov K.V., Kaplina (Demekhova) M.Yu., Kononova Yu.A., Kozlova V.V., Schastlivtsev I.V.

More about the authors

Journal: Journal of Venous Disorders. 2024;18(4): 339‑350

DOI: 10.17116/flebo202418041339

Read: 1378 times

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Table of contents

PHLEBOLYMPHEDEMA: MODERN VIEWS AND METHODS OF CORRECTION
PHLEBOLYMPHEDEMA: MODERN VIEWS AND METHODS OF CORRECTION

To cite this article:

Lobastov KV, Kaplina (Demekhova) MYu, Kononova YuA, Kozlova VV, Schastlivtsev IV. Phlebolymphedema: Modern Views and Methods of Correction. Journal of Venous Disorders. 2024;18(4):339‑350. (In Russ.)
https://doi.org/10.17116/flebo202418041339

 
Подписка 2026 Флебология (Journal of Venous Disorders)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

OBJECTIVE

To summarize the available data on the role of lymphatic insufficiency in CVI and its correction using CVD treatment approaches.

MATERIAL AND METHODS

We reviewed the PubMed and eLibrary databases using the keywords «phlebolymphedema», as well as analyzed available articles.

RESULTS

Revising the Starling’s law excluding fluid reabsorption at the venous end of the capillary and placing responsibility for fluid drainage on lymphatic system is important for the concept of phlebolymphedema. Progressive venous hypertension and increased plasma filtration can lead to functional insufficiency and damage to lymphatic system. Available data confirm progressive impairment of lymphatic outflow in parallel with progression of CVD. Modern methods of morphofunctional assessment of superficial lymphatic system, in particular ICG lymphography, allows us to take a new look at pathogenesis of CVI. Standard methods of CVD treatment can have a positive effect on lymphatic outflow, but available data are contradictory. Therapeutic effect of compression therapy is mainly limited to fluid movement through the interstitium towards intact lymphatic vessels. Various drugs including micronized purified flavonoid fraction demonstrate a positive effect on lymphatic drainage. Appropriate therapy is followed by effective relief of venospecific subjective symptoms, chronic edema and trophic disorders. Surgery for superficial and deep veins can improve lymphatic drainage, but clinical results are naturally worse in case of lymphatic insufficiency.

CONCLUSION

Damage to lymphatic system is essential for progressive forms of CVD that emphasizes the need for further study of this issue and development of prevention methods.

Keywords:

lymphatic system
lymphedema
phlebolymphedema
edema
Starling’s law

Authors:

Lobastov K.V.

Pirogov Russian National Research Medical University

Kaplina (Demekhova) M.Yu.

Pavlov First Saint Petersburg State Medical University

Kononova Yu.A.

Central Polyclinic No. 1 of the Ministry of Internal Affairs of Russia

Kozlova V.V.

Pirogov Russian National Research Medical University

Schastlivtsev I.V.

Pirogov Russian National Research Medical University

Received:

28.08.2024

Accepted:

05.09.2024

Close metadata

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