Aim. To analyse the results of the application of the modern surgical strategies for the treatment of chronic venous diseases (CVD) of the lower extremities based at an one-day suite. Material and methods. The combined treatment was given to 312 patients including 300 (96.2%) women and 12 (3.8%) men with functional class C1—C4 CVD. 37 (1.8%) patients underwent endovenous laser ablation (EVLA) with crossectomy, 48 (15.4%) were treated by radiofrequency ablation (RFFA) with crossectomy, and 23 (7.4%) by transcutaneous laser photocoagulation of teleangiectasias. Ten patients with the diameter of the trunk of the great saphenous vein (GSV) near the opening 10 mm or more underwent combined phlebectomy. 194 (62.2%) the patients were treated using various variants of sclerotherapy (with the application of a liquid solution, microfoam, and echosclerotherapy). Results. Recanalization occurred in two (10%) patients who had undergone endovenous laser ablation of the great saphenous vein and in one case after EVLA of  the small saphenous vein. RFFA resulted in recanalization in 1 (4%) patient. Microsclerotherapy of teleangiectasias and reticular veins yielded good results in 88.7% of the patients, satisfactory and poor results in 9 and 2.3% cases respectively. Sclerotherapy of minor varicose veins using microfoam resulted in 68% cases of complete obliteration following a single therapeutic procedure and in 17.7% cases after two procedures. The effect of microfoam sclerotherapy was absent in 14.5% of the patients. The primary treatment by such method of minor varicose veins non-visualizable and unpalpatable in the horizontal position under echographic control made it possible to obliterate 76% of the 25 sclerosable vessels; another 16% were obliterated after the secondary treatment. Conclusion. The use of the modern minimally invasive technologies permits to substantially broaden the scope of treatments of the patients presenting with CVD based at an one-day suite. Good functional and aesthetic results of the combined treatment of chronic venous disease of the lower extremities as well as the reduction to a minimum of the risk of CVD complications can be achieved only with the use of adequate and correct combinations of modern techologies by skilled and experienced specialists.