Modern approaches to the management of complications of extrahepatic portal hypertension due to extensive portal system thrombosis

Fedorchenko S.V.; Manukyan G.V.; Malov S.L.; Fandeyev E.E.; Mazanova D.N.; Kitsenko E.A.

doi:https://doi.org/10.17116/endoskop20263202153

Fedorchenko S.V.

Petrovsky Russian Research Center of Surgery, Moscow, Russia

ORCID: 0009-0003-0316-5409

Manukyan G.V.

Petrovsky Russian Research Center of Surgery, Moscow, Russia

ORCID: 0000-0001-8064-1964

Malov S.L.

Petrovsky Russian Research Center of Surgery, Moscow, Russia

ORCID: 0000-0002-8431-9179

Fandeyev E.E.

Petrovsky Russian Research Center of Surgery, Moscow, Russia

ORCID: 0000-0002-7554-6345

Mazanova D.N.

Petrovsky Russian Research Center of Surgery, Moscow, Russia

ORCID: 0009-0001-1569-9980

Kitsenko E.A.

Petrovsky Russian Research Center of Surgery, Moscow, Russia

ORCID: 0000-0002-8268-3129

Modern approaches to the management of complications of extrahepatic portal hypertension due to extensive portal system thrombosis

Authors:

Fedorchenko S.V., Manukyan G.V., Malov S.L., Fandeyev E.E., Mazanova D.N., Kitsenko E.A.

More about the authors

Journal: Endoscopic Surgery. 2026;32(2): 53‑62

DOI: 10.17116/endoskop20263202153

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To cite this article:

Fedorchenko SV, Manukyan GV, Malov SL, Fandeyev EE, Mazanova DN, Kitsenko EA. Modern approaches to the management of complications of extrahepatic portal hypertension due to extensive portal system thrombosis. Endoscopic Surgery. 2026;32(2):53‑62. (In Russ.)
https://doi.org/10.17116/endoskop20263202153

Подписка 2026 Эндоскопическая хирургия (Endoscopic Surgery)

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Abstract:

This article provides a systematic review of current literature on extensive portal system thrombosis. It examines etiology, pathogenesis, classifications, clinical manifestations, diagnosis, and comprehensive management of this condition. The particular focus is placed on the differentiated approach to a treatment strategy—ranging from anticoagulant therapy to endovascular and surgical interventions. The relevance of the topic is underscored by the high frequency of life-threatening complications, such as gastroesophageal variceal bleeding, portal cholangiopathy and mesenteric ischemia. This work aims to synthesize contemporary knowledge on the management of patients with portal system thrombosis to optimize diagnostic and therapeutic algorithms.

Keywords:

portal system thrombosis

extrahepatic portal hypertension

anticoagulant therapy

endoscopic ligation

esophagogastric variceal bleeding

Authors:

Fedorchenko S.V.

Petrovsky Russian Research Center of Surgery, Moscow, Russia

ORCID: 0009-0003-0316-5409

Manukyan G.V.

Petrovsky Russian Research Center of Surgery, Moscow, Russia

ORCID: 0000-0001-8064-1964

Malov S.L.

Petrovsky Russian Research Center of Surgery, Moscow, Russia

ORCID: 0000-0002-8431-9179

Fandeyev E.E.

Petrovsky Russian Research Center of Surgery, Moscow, Russia

ORCID: 0000-0002-7554-6345

Mazanova D.N.

Petrovsky Russian Research Center of Surgery, Moscow, Russia

ORCID: 0009-0001-1569-9980

Kitsenko E.A.

Petrovsky Russian Research Center of Surgery, Moscow, Russia

ORCID: 0000-0002-8268-3129

Received:

29.11.2025

Accepted:

12.12.2025

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References:

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