The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-4329
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2026
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Drobyazgin E.A.

Novosibirsk State Medical University;
Novosibirsk State Regional Clinical Hospital;
Meshalkin National Medical Research Center

Chikinev Yu.V.

Novosibirsk State Medical University;
Novosibirsk State Regional Clinical Hospital

Mitko N.I.

Novosibirsk State Medical University

Quality of Life of Patients with Achalasia After Minimally Invasive Interventions

Authors:

Drobyazgin E.A., Chikinev Yu.V., Mitko N.I.

More about the authors

Journal: Russian Journal of Evidence-Based Gastroenterology. 2023;12(3): 43‑50

DOI: 10.17116/dokgastro20231203143

Read: 1770 times

Contact the author
Table of contents

QUALITY OF LIFE OF PATIENTS WITH ACHALASIA AFTER MINIMALLY INVASIVE INTERVENTIONS
QUALITY OF LIFE OF PATIENTS WITH ACHALASIA AFTER MINIMALLY INVASIVE INTERVENTIONS

To cite this article:

Drobyazgin EA, Chikinev YuV, Mitko NI. Quality of Life of Patients with Achalasia After Minimally Invasive Interventions. Russian Journal of Evidence-Based Gastroenterology. 2023;12(3):43‑50. (In Russ.)
https://doi.org/10.17116/dokgastro20231203143

Подписка 2026 Доказательная гастроэнтерология (Russian Journal of Evidence-Based Gastroenterology)
МСФ на ЯМ
Использование инфографики авторами научных работ
Close metadata
Abstract:

OBJECTIVE

To evaluate the quality of life of achalasia patients following minimally invasive interventions one year after the procedures.

MATERIAL AND METHODS

Between 2010 and 2019, individuals aged 18 to 76 with achalasia underwent minimally invasive surgical interventions. The patients were categorized into two groups: the main group underwent peroral endoscopic myotomy (POEM), while the comparison group underwent laparoscopic esophagocardiofundoplasty with anterior partial fundoplication based on Hill’s technique. All patients were assessed using the Eckardt score, SF-36, GIQLI, and GERD questionnaires between 1- and 4-years post-surgery.

RESULTS

Patients treated with POEM exhibited significantly lower Eckardt scores compared to those treated with esophagocardiofundoplasty (p=0.029711). Gastroesophageal reflux was 5.4% less prevalent in the POEM group (p=0.06). The GIQLI questionnaire demonstrated that long-term post-surgery results favored the main group in terms of key indicators and the overall quality of life index. Regarding the SF-36 questionnaire, the physical and psychological components of health were significantly higher in the main group’s long-term post-surgery results compared to the second group.

CONCLUSION

Patients treated with POEM experienced a higher quality of life than those treated with minimally invasive laparoscopic intervention involving cardia and partial fundoplication. Notably, the occurrence of gastroesophageal reflux did not differ significantly between patient groups. Subsequent follow-up is necessary to establish indications for each intervention type.

Keywords:

esophageal achalasia
peroral endoscopic myotomy
quality of life
endoscopy
minimally invasive surgery

Authors:

Drobyazgin E.A.

Novosibirsk State Medical University;
Novosibirsk State Regional Clinical Hospital;
Meshalkin National Medical Research Center

Chikinev Yu.V.

Novosibirsk State Medical University;
Novosibirsk State Regional Clinical Hospital

Mitko N.I.

Novosibirsk State Medical University

Received:

12.07.2022

Accepted:

09.08.2023

Close metadata

References:

  1. Cho YK, Kim SH. Current Status of Peroral Endoscopic Myotomy. Clinical Endoscopy. 2018;51(1):13-18.  https://doi.org/10.5946/ce.2017.165
  2. Schaheen LW, Sanchez MV, Luketich JD. Peroral Endoscopic Myotomy for Achalasia. Thoracic Surgery Clinics. 2018;28(4):499-506.  https://doi.org/10.1016/j.thorsurg.2018.07.005
  3. Xu S, Chai N, Tang X, Linghu E, Li L, Wang S, Zhang X. Surgical Endoscopy. 2021;35(7):3732-3743. https://doi.org/10.1007/s00464-020-07864-2
  4. Kaibysheva VO, Nikonov EL, Plakhov RV, Fedorov ED, Shapovalyants SG. Comparison of the modern treatment methods for esophageal achalasia. Dokazatel’naya gastroenterologiya. 2019; 8(4-5):44-60. (In Russ.). https://doi.org/10.17116/dokgastro2019804-05144
  5. Feng J, Ali RW, Hao JY, Kong GX, Yang LH, Huang XJ. Esophagus. 2020;17(1):11-18.  https://doi.org/10.1007/s10388-019-00693-w
  6. Ghazaleh S, Beran A, Khader Y, Nehme C, Chuang J, Sharma S, Aziz M, Khan Z, Elzanaty AM, Burlen J, Nawras A. Short versus standard peroral endoscopic myotomy for esophageal achalasia: a systematic review and meta-analysis. Annals of Gastroenterology. 2021;34(5):634-642.  https://doi.org/10.20524/aog.2021.0644
  7. Ponds FA, Fockens P, Lei A, Neuhaus H, Beyna T, Kandler J, Frieling T, Chiu PWY, Wu JCY, Wong VWY, Costamagna G, Familiari P, Kahrilas PJ, Pandolfino JE, Smout AJPM, Bredenoord AJ. Effect of Peroral Endoscopic Myotomy vs Pneumatic Dilation on Symptom Severity and Treatment Outcomes among Treatment-Naive Patients with Achalasia: A Randomized Clinical Trial. JAMA. 2019;322(2):134-144.  https://doi.org/10.1001/jama.2019.8859
  8. Zheng Z, Zhao C, Su S, Fan X, Zhao W, Wang B, Jin H, Zhang L, Wang T, Wang B. Peroral endoscopic myotomy versus pneumatic dilation — result from a retrospective study with 1-year follow-up. Zeitschrift für Gastroenterologie. 2019;57(3):304-311.  https://doi.org/10.1055/a-0821-7232
  9. Zhong C, Tan S, Huang S, Lü M, Peng Y, Fu X, Tang X. Peroral endoscopic myotomy versus pneumatic dilation for achalasia: a systematic review and meta-analysis. European Journal of Gastroenterology & Hepatology. 2020;32(11):1413-1421. https://doi.org/10.1097/MEG.0000000000001800
  10. Dirks RC, Kohn GP, Slater B, Whiteside J, Rodriguez NA, Docimo S, Pryor A, Stefanidis D; SAGES guidelines committee. Is peroral endoscopic myotomy (POEM) more effective than pneumatic dilation and Heller myotomy? A systematic review and meta-analysis. Surgical Endoscopy. 2021;35(5):1949-1962. https://doi.org/10.1007/s00464-021-08353-w
  11. Olson MT, Triantafyllou T, Singhal S. A Decade of Investigation: Peroral Endoscopic Myotomy Versus Laparoscopic Heller Myotomy for Achalasia. Journal of Laparoendoscopic and Advanced Surgical Techniques. Part A. 2019;29(9):1093-1104. https://doi.org/10.1089/lap.2019.0242
  12. Anishcenko VV, Kovgan YuM, Nalbandyan ag, Kim DA. Current outcome analysis of treatment of patients with III-IV stage esophageal achalasia. Endoscopicheskaya Khirurgiya. 2017; 23(5):3-6. (In Russ.).
  13. Nedoluzhko IYu, Shishin KV, Kazakova SS, Kurushkina NA, Shumkina LV, Bordin DS. Comparison of the Results of the Oral Endoscopic Myotomy and Laparoscopic Esophagogastromyotomy in Patients with Esophageal Achalasia. Doctor.Ru. 2018;3(147): 37-41. (In Russ.).
  14. Gabriel SA, Dynko VYu, Bespechny MV, Guchetl AYa, Tlekhuray RM. Clinical efficiency of POEM operation in patients with achalasia of cardias. Innovacionnaya medicina Kubani. 2020; 17(1):52-55. (In Russ.). https://doi.org/10.35401/2500-0268-2020-17-1-52-55
  15. Zhong C, Tan S, Ren Y, Lü M, Peng Y, Fu X, Tang X. Quality of Life Following Peroral Endoscopic Myotomy for Esophageal Achalasia: A Systematic Review and Meta-Analysis. Annals of Thoracic and Cardiovascular Surgery. 2020;26(3):113-124.  https://doi.org/10.5761/atcs.ra.19-00273
  16. Tefas C, Ababneh RM. Peroral Endoscopic Myotomy Versus Heller Myotomy for Achalasia: Pros and Cons. Chirurgia (Bucur). 2018;113(2):185-191.  https://doi.org/10.21614/chirurgia.113.2.185
  17. Miftahussurur M, Tandan M, Makmun D, Nabi Z. Peroral Endoscopic Myotomy in a Patient with Achalasia Cardia with Prior Heller’s Myotomy. Case Reports in Gastroenterology. 2020;14(1):48-55. 
  18. Tan S, Zhong C, Ren Y, Luo X, Xu J, Fu X, Peng Y, Tang X. Efficacy and Safety of Peroral Endoscopic Myotomy in Achalasia Patients with Failed Previous Intervention: A Systematic Review and Meta-Analysis. Gut and Liver. 2021;15(2):153-167.  https://doi.org/10.5009/gnl19234
  19. Jin H, Wang B, Zheng ZQ, Zhang LL, Chen QY, Zhao CS, Wang BM, Zhao W. Peroral endoscopic myotomy for the treatment of achalasia after failed pneumatic dilation. Surgical Endoscopy. 2021;35(12):6960-6968. https://doi.org/10.1007/s00464-020-08207-x
  20. Sanaka MR, Khoudari G, Parikh M, Thota PN, Lopez R, Gupta N, Gabbard S, Ray M, Murthy S, Raja S. Peroral endoscopic myotomy is highly effective for achalasia patients with recurrent symptoms after pneumatic dilatation. Surgical Endoscopy. 2021; 35(6):2965-2975. https://doi.org/10.1007/s00464-020-07737-8
  21. Smirnov AA, Lubchenko ME, Kiriltseva MM, Dvoretskiy SY, Vasilevskij DI, Semenikhin KD, Burakov AN, Kaibysheva VO, Bagnenko SF. Complications of peroral endoscopic myotomy. 3-year experience of one center. Experimental and Clinical Gastroenterology. 2018;158(10):57-61. 
  22. Gonzalez JM, Monino L, Ah-Soune P, Vitton V, Barthet M. Peroral endoscopic myotomy (POEM) for dysphagia and esophageal motor disorder after antireflux fundoplication. Endoscopy. 2020;52(7):583-588.  https://doi.org/10.1055/a-1147-1348
  23. Gong EJ, Na HK, Ahn JY, Jung KW, Kim DH, Choi KD, Song HJ, Jung HY. Prospective evaluation of the efficacy of peroral endoscopic myotomy in patients with achalasia. Medicine (Baltimore). 2021;100(23):e26248. https://doi.org/10.1097/MD.0000000000026248
  24. Petrov RV, Fajardo RA, Bakhos CT, Abbas AE. Peroral endoscopic myotomy: techniques and outcomes. Shanghai Chest. 2021;5:14.  https://doi.org/10.21037/shc.2020.02.02
  25. Shiwaku H, Inoue H, Sato H, Onimaru M, Minami H, Tanaka S, Sato C, Ogawa R, Okushima N, Yokomichi H. Peroral endoscopic myotomy for achalasia: a prospective multicenter study in Japan. Gastrointestinal Endoscopy. 2020;91(5):1037-1044.e2.  https://doi.org/10.1016/j.gie.2019.11.020
  26. Zhang WG, Chai NL, Zhai YQ, Linghu EQ, Li HK. Long-term outcomes of peroral endoscopic myotomy in achalasia patients with a minimum follow-up of 7 years. Chinese Medical Journal. 2020;133(8):996-998.  https://doi.org/10.1097/CM9.0000000000000735
  27. Bechara R, Inoue H, Shimamura Y, Reed D. Gastroesophageal reflux disease after peroral endoscopic myotomy: lest we forget what we already know. Diseases of the Esophagus. 2019;32(12):doz106. https://doi.org/10.1093/dote/doz106
  28. Schlottmann F, Luckett DJ, Fine J, Shaheen NJ, Patti MG. Laparoscopic Heller Myotomy Versus Peroral Endoscopic Myotomy (POEM) for Achalasia: A Systematic Review and Meta-analysis. Annals of Surgery. 2018;267(3):451-460.  https://doi.org/10.1097/SLA.0000000000002311
  29. Hernández-Mondragón OV, Solórzano-Pineda OM, González-Martínez M, Blancas-Valencia JM. Gastroesophageal reflux disease after peroral endoscopic myotomy: Short-term, medium-term, and long-term results. Revista de Gastroenterología de México. 2020;85(1):4-11.  https://doi.org/10.1016/j.rgmx.2019.04.001
  30. Inoue H, Shiwaku H, Kobayashi Y, Chiu PWY, Hawes RH, Neuhaus H, Costamagna G, Stavropoulos SN, Fukami N, Seewald S, Onimaru M, Minami H, Tanaka S, Shimamura Y, Santi EG, Grimes K, Tajiri H. Statement for gastroesophageal reflux disease after peroral endoscopic myotomy from an international multicenter experience. Esophagus. 2020;17(1):3-10.  https://doi.org/10.1007/s10388-019-00689-6
Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.