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Korotaeva A.A.

Research Centre for Medical Genetics

Borunova A.A.

N.N. Blokhin National Medical Research Center of Oncology

Kuzevanova A.Yu.

Research Centre for Medical Genetics

Zabotina T.N.

N.N. Blokhin National Medical Research Center of Oncology

Alimov A.A.

Research Centre for Medical Genetics

Molecular mechanisms of impaired antigenic presentation as a cause of tumor escape from immune surveillance

Authors:

Korotaeva A.A., Borunova A.A., Kuzevanova A.Yu., Zabotina T.N., Alimov A.A.

More about the authors

Journal: Russian Journal of Archive of Pathology. 2023;85(6): 76‑83

DOI: 10.17116/patol20238506176

Read: 3093 times

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Table of contents

MOLECULAR MECHANISMS OF IMPAIRED ANTIGENIC PRESENTATION AS A CAUSE OF TUMOR ESCAPE FROM IMMUNE SURVEILLANCE
MOLECULAR MECHANISMS OF IMPAIRED ANTIGENIC PRESENTATION AS A CAUSE OF TUMOR ESCAPE FROM IMMUNE SURVEILLANCE

To cite this article:

Korotaeva AA, Borunova AA, Kuzevanova AYu, Zabotina TN, Alimov AA. Molecular mechanisms of impaired antigenic presentation as a cause of tumor escape from immune surveillance. Russian Journal of Archive of Pathology. 2023;85(6):76‑83. (In Russ.)
https://doi.org/10.17116/patol20238506176

Подписка 2026 Архив патологии (Russian Journal of Archive of Pathology)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

The review summarizes data on the features of antigen presentation in tumor cells. The molecular mechanisms of the antitumor immune response are considered with an emphasis on the ability of tumor cells to avoid the action of immune surveillance. The features of expression of MHC molecules depending on treatment regimens are provided. Ways to improve existing and create new treatment regimens aimed at elimination of tumor cells because of antitumor immune response are discussed.

Keywords:

immunotherapy
antigen
major histocompatibility complex
expression
immune response

Authors:

Korotaeva A.A.

Research Centre for Medical Genetics

Borunova A.A.

N.N. Blokhin National Medical Research Center of Oncology

Kuzevanova A.Yu.

Research Centre for Medical Genetics

Zabotina T.N.

N.N. Blokhin National Medical Research Center of Oncology

Alimov A.A.

Research Centre for Medical Genetics

Received:

25.08.2023

Accepted:

20.09.2023

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