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Cherniaev A.L.

FGU "NII pul'monologii" FMBA Rossii

Voĭtkovskaia K.S.

FGBU "NII morfologii cheloveka" RAMN, Moskva

Tarabrin E.A.

Nauchno-issledovatel'skiĭ institut skoroĭ pomoshchi im. N.V. Sklifosovskogo, Moskva

Avdeev S.N.

I.M. Sechenov First Moscow State Medical University under the Ministry of Health of the Russia, Moscow, Russia, 119991;
Pulmonology Research Institute under the Federal Medical and Biological Agency of Russia, Moscow, Russia, 115682

Karchevskaia N.A.

N.V. Sklifosovskiy Institute for Emergency Care, Moscow Health Department;
Institute of Pulmonology, Federal Medical and Biological Agency of Russia, Moscow, Russia

Samsonova M.V.

FGU "NII pul'monologii" FMBA Rossii

Pathomorphological features of pulmonary Langerhans cell histiocytosis

Authors:

Cherniaev A.L., Voĭtkovskaia K.S., Tarabrin E.A., Avdeev S.N., Karchevskaia N.A., Samsonova M.V.

More about the authors

Journal: Russian Journal of Archive of Pathology. 2014;76(6): 56‑60

DOI: 10.17116/patol201476656-60

Read: 2567 times

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Table of contents

PATHOMORPHOLOGICAL FEATURES OF PULMONARY LANGERHANS CELL HISTIOCYTOSIS
PATHOMORPHOLOGICAL FEATURES OF PULMONARY LANGERHANS CELL HISTIOCYTOSIS

To cite this article:

Cherniaev AL, Voĭtkovskaia KS, Tarabrin EA, Avdeev SN, Karchevskaia NA, Samsonova MV. Pathomorphological features of pulmonary Langerhans cell histiocytosis. Russian Journal of Archive of Pathology. 2014;76(6):56‑60. (In Russ.)
https://doi.org/10.17116/patol201476656-60

 
Подписка 2026 Архив патологии (Russian Journal of Archive of Pathology)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

The paper provides the clinical and X-ray characteristics of pulmonary Langerhans cell histiocytosis (PLCH). It describes pulmonary pathohistological changes in this disease, characterizes the cellular composition of granuloma, and gives methods that can verify the diagnosis of PLCH. A case of PLCH with severe respiratory failure, for which bilateral lung transplantation and histological examination of removed lungs have been made, is described.

Keywords:

pulmonary Langerhans cell histiocytosis
diagnosis
pathologic anatomy

Authors:

Cherniaev A.L.

FGU "NII pul'monologii" FMBA Rossii

Voĭtkovskaia K.S.

FGBU "NII morfologii cheloveka" RAMN, Moskva

Tarabrin E.A.

Nauchno-issledovatel'skiĭ institut skoroĭ pomoshchi im. N.V. Sklifosovskogo, Moskva

Avdeev S.N.

I.M. Sechenov First Moscow State Medical University under the Ministry of Health of the Russia, Moscow, Russia, 119991;
Pulmonology Research Institute under the Federal Medical and Biological Agency of Russia, Moscow, Russia, 115682

Karchevskaia N.A.

N.V. Sklifosovskiy Institute for Emergency Care, Moscow Health Department;
Institute of Pulmonology, Federal Medical and Biological Agency of Russia, Moscow, Russia

Samsonova M.V.

FGU "NII pul'monologii" FMBA Rossii

Close metadata

References:

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  2. Langerhans P. Uber die Nerven der menschlichen Haut. Virchows Arch. Pathol. Anat. 1868; 44: 325-37.
  3. Birbeck M.S., Breathnach A.D., Everall J.D. An electron microscope study of basal melanocytes and high-level clear cells (Langerhans cells) in vitiligo. J. Invest. Dermatol. 1961; 37: 51-64.
  4. Hammar S.P., Allen T.C. Histiocytosis and Storage Diseases. In: Dail and Hammar's Pulmonary Pathology. 3rd edition. Ed. P.T. Cagle, A.E. Fraire, J.F. Tomashefski, Jr., C.F. Farver. Springer Science+Business Media, LLC; 2008.
  5. Vermaelen K., Pauwels R. Pulmonary dendritic cells. Am. J. Respir. Crit. Care Med. 2005; 172: 530-51.
  6. Yu R.C., Cho C., Buluwela L., Chu A.C. Clonal proliferation of Lahgerhans cells in Langerhans cell histiocytosis. Lancet. 1994; 343: 767-8.
  7. Vassallo R., Ryu J., Schroeder D.R. et al. Clinical outcomes of pulmonary Langerhans'-cell histiocytosis in adults. N. Engl. J. Med. 2002; 346: 484-90.
  8. Juvet S.C., Hwang D., Downey G.P. Rare lung diseases III: Pulmonary Langerhans' cell histiocytosis. Can. Respir. J. 2010; 17 (3): 55-62.
  9. Kambouchner M., Basset F., Marchal J. et al. Three-dimensional characterization of pathologic lesions in pulmonary langerhans cell histiocytosis. Am. J. Respir. Crit. Care Med. 2002; 166: 1483-90.
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