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Bukreeva G.G.

Sokolov North-Western Research Clinical Center

Simutis I.S.

Sokolov North-Western District Scientific Clinical Center;
Mechnikov North-Western State Medical University

Abramovskiy S.V.

Sokolov North-Western Research Clinical Center

Prishlyak V.B.

Sokolov North-Western Research Clinical Center

Ratnikov V.A.

Sokolov North-Western Research Clinical Center;
St. Petersburg State Medical University

Shcheglov A.N.

Central Clinical Hospital with Polyclinic of Administrative Directorate of the President of the Russian Federation

Clinical effect of selective hemosorption of cytokines in patients with severe COVID-19: a systematic review

Authors:

Bukreeva G.G., Simutis I.S., Abramovskiy S.V., Prishlyak V.B., Ratnikov V.A., Shcheglov A.N.

More about the authors

Journal: Russian Journal of Anesthesiology and Reanimatology. 2024;(5): 103‑111

DOI: 10.17116/anaesthesiology2024051103

Read: 1201 times

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Table of contents

CLINICAL EFFECT OF SELECTIVE HEMOSORPTION OF CYTOKINES IN PATIENTS WITH SEVERE COVID-19: A SYSTEMATIC REVIEW
CLINICAL EFFECT OF SELECTIVE HEMOSORPTION OF CYTOKINES IN PATIENTS WITH SEVERE COVID-19: A SYSTEMATIC REVIEW

To cite this article:

Bukreeva GG, Simutis IS, Abramovskiy SV, Prishlyak VB, Ratnikov VA, Shcheglov AN. Clinical effect of selective hemosorption of cytokines in patients with severe COVID-19: a systematic review. Russian Journal of Anesthesiology and Reanimatology. 2024;(5):103‑111. (In Russ.)
https://doi.org/10.17116/anaesthesiology2024051103

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Abstract:

OBJECTIVE

To evaluate the strategies and role of selective hemosorption of cytokines in the treatment of severe COVID-19 infection.

MATERIAL AND METHODS. S

Ystematic searching for available literature data on selective hemosorption of cytokines in patients with COVID-19 was performed in the PubMed and Elibrary databases.

RESULTS

We found 264 articles according to keywords. Considering inclusion criteria, we enrolled 22 full-text articles. Of these, four manuscripts were selected to estimate the effect of isolated selective cytokine hemosorption. Three articles were selected to study the effect of hemosorption combined with renal replacement therapy.

CONCLUSION. H

Eterogeneous data without control group in most studies and predominant small samples do not provide an opportunity to draw an unambiguous conclusion about clinical effect of various methods of efferent therapy. However, selective hemosorption of cytokines in the treatment of COVID-19 reduces mortality.

Keywords:

COVID-19
cytokine storm
cytokine sorption
hemoperfusion
treatment of COVID-19
cytokine adsorption

Authors:

Bukreeva G.G.

Sokolov North-Western Research Clinical Center

Simutis I.S.

Sokolov North-Western District Scientific Clinical Center;
Mechnikov North-Western State Medical University

Abramovskiy S.V.

Sokolov North-Western Research Clinical Center

Prishlyak V.B.

Sokolov North-Western Research Clinical Center

Ratnikov V.A.

Sokolov North-Western Research Clinical Center;
St. Petersburg State Medical University

Shcheglov A.N.

Central Clinical Hospital with Polyclinic of Administrative Directorate of the President of the Russian Federation

Received:

08.08.2023

Accepted:

11.07.2024

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