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Kaprin A.D.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of Ministry of Russia;
Peoples’ Friendship University of Russia

Khoronenko V.E.

P.A. Herzen Moscow Oncology Research Institute, Branch, National Medical Radiology Research Center

Zakharenkova Yu.S.

Herzen Moscow Oncology Research Institute — Branch of the National Medical Research Center of Radiology

Gameeva E.V.

Herzen Moscow Oncology Research Institute — Branch Campus of the National Medical Radiology Research Center

Treatment of cancer patients during COVID-19 pandemic

Authors:

Kaprin A.D., Khoronenko V.E., Zakharenkova Yu.S., Gameeva E.V.

More about the authors

Journal: Russian Journal of Anesthesiology and Reanimatology. 2021;(2): 117‑123

DOI: 10.17116/anaesthesiology2021021117

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To cite this article:

Kaprin AD, Khoronenko VE, Zakharenkova YuS, Gameeva EV. Treatment of cancer patients during COVID-19 pandemic. Russian Journal of Anesthesiology and Reanimatology. 2021;(2):117‑123. (In Russ.)
https://doi.org/10.17116/anaesthesiology2021021117

Подписка 2025 (АиР)
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BACKGROUND

Cancer patients comprise one of the most vulnerable subpopulations under COVID-19 pandemic, since the incidence of COVID-19 among cancer patients exceeds this value in general population. Risk of severe COVID-19 infection and mortality is higher in patients with cancer.

OBJECTIVE

Searching and retrospective analysis of risk factors of mortality in cancer patients with COVID-19 infection.

MATERIAL AND METHODS

A retrospective analysis included 31 cancer patients who underwent surgery at the Herzen Moscow Oncology Research Institute. COVID-19 was detected in postoperative period in each patient. We have compared survivors and non-survivors and assessed the risk factors of mortality.

RESULTS

COVID-19 in postoperative period occurred in 31 (4.74%) out of 722 patients. Hypertension (74.2%, n=23) and cardiac diseases including coronary artery disease and chronic heart failure (19.35%, n=6) were the most common comorbidities. Incidence of coronavirus infection was the highest among patients with colorectal cancer (16.13%, n=5), kidney cancer (16.13%, n=5) and lung cancer (12.9%, n=4). We found the following risk factors of mortality in cancer patients with COVID-19: CHD (OR 7.0, 95% CI 1.014-48.313, p<0.05), COPD (OR 15.000, 95% CI 1.397-161.052, p<0.05), lung cancer (OR 12.000, 95% CI 1.074-134.116, p<0.05), and mechanical ventilation (OR 135.000, 95% CI 7.485-2435.007, p<0.05).

Keywords:

COVID-19
cancer patients
risk factors
chronic diseases

Authors:

Kaprin A.D.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of Ministry of Russia;
Peoples’ Friendship University of Russia

Khoronenko V.E.

P.A. Herzen Moscow Oncology Research Institute, Branch, National Medical Radiology Research Center

Zakharenkova Yu.S.

Herzen Moscow Oncology Research Institute — Branch of the National Medical Research Center of Radiology

Gameeva E.V.

Herzen Moscow Oncology Research Institute — Branch Campus of the National Medical Radiology Research Center

Received:

30.11.2020

Accepted:

25.12.2020

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