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Kalashnikova L.A.

Research Center of Neurology

Danilova M.S.

Research Center of Neurology

Gubanova M.V.

Research Center of Neurology

Dobrynina L.A.

Research Center of Neurology

Dreval M.V.

Research Center of Neurology

Krotenkova M.V.

Research Center of Neurology

Aneurysms and pathological tortuosity of the internal carotid and vertebral arteries in patients with dissection of these vessels: a results of long-term study

Authors:

Kalashnikova L.A., Danilova M.S., Gubanova M.V., Dobrynina L.A., Dreval M.V., Krotenkova M.V.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2021;121(12): 7‑12

DOI: 10.17116/jnevro20211211217

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Table of contents

ANEURYSMS AND PATHOLOGICAL TORTUOSITY OF THE INTERNAL CAROTID AND VERTEBRAL ARTERIES IN PATIENTS WITH DISSECTION OF THESE VESSELS: A RESULTS OF LONG-TERM STUDY
ANEURYSMS AND PATHOLOGICAL TORTUOSITY OF THE INTERNAL CAROTID AND VERTEBRAL ARTERIES IN PATIENTS WITH DISSECTION OF THESE VESSELS: A RESULTS OF LONG-TERM STUDY

To cite this article:

Kalashnikova LA, Danilova MS, Gubanova MV, Dobrynina LA, Dreval MV, Krotenkova MV. Aneurysms and pathological tortuosity of the internal carotid and vertebral arteries in patients with dissection of these vessels: a results of long-term study. S.S. Korsakov Journal of Neurology and Psychiatry. 2021;121(12):7‑12. (In Russ.)
https://doi.org/10.17116/jnevro20211211217

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

OBJECTIVE

To study the frequency, angiographic and clinical features of aneurysms and tortuosity (T) in patients with internal carotid artery (ICA) and vertebral artery (VA) dissection.

MATERIAL AND METHODS

Three hundred and twenty-seven patients (average age — 37.8±9.1 years, women — 57%) with ICA/VA dissection verified by neuroimaging were studied. Repeated neuroimaging in 2.4±3.3 years was performed in 254 patients. In one case, tortuous ICA fragment resected at the surgery complicated by dissection was histologically studied.

RESULTS

ICA/VA aneurysms were found in 46 (14%) patients. At repeated neuroimaging aneurysms did not change (38%), increased (11%) or decreased in size (8%), were not detected (38%) or were detected for the first time (5%). Patients with aneurysms compared with those without aneurysms more often had multiple dissections (44% vs. 20%, p=0.001) and T (35% vs. 13%, p=0.001), but less frequently the artery lumen occlusion in the acute period (15% vs. 40%, p=0.001). T was found in 53 (16%) patients. Patients with T compared with patients without T were older (40.6±8.1 vs. 37.3±9.3 years, p=0.039), more often had aneurysms (30% vs. 11%, p=0.001) and recanalization of occlusion observed in the acute period (89% vs. 54%, p=0.006). Dissection more often occurred in tortuous than in non-tortuous artery (79% vs 21%, p=0.001). During 4.8±3.6 years of follow-up, TIA developed inone patient (2%) with an aneurysm. Histological examination of tortuous ICA fragment, which also contained a small aneurysm, revealed dysplastic changes.

CONCLUSION

The association between aneurism and T in patients with ICA/VA dissection suggests their common basis — the arterial wall weakness due to dysplasia. Age-related changes are also important for T development. T is a risk factor for ICA/VA dissection. Aneurysms formed after ICA/VA dissection have a benign course.

Keywords:

dissection
internal carotid artery
vertebral artery
dissecting aneurism
tortuosity

Authors:

Kalashnikova L.A.

Research Center of Neurology

Danilova M.S.

Research Center of Neurology

Gubanova M.V.

Research Center of Neurology

Dobrynina L.A.

Research Center of Neurology

Dreval M.V.

Research Center of Neurology

Krotenkova M.V.

Research Center of Neurology

Received:

25.08.2021

Accepted:

27.08.2021

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