The assessment of efficacy and tolerability of the complex therapy of low back pain

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OBJECTIVE

To assess the efficacy of the complex therapy of nonspecific low back pain (LBP) with amelotex, calmirex, kompligamB in comparison with the monotherapy with amelotex.

MATERIAL AND METHODS

This observational study included sixty patients, aged 53.73±11.84 53 years, with nonspecific LBP. Patients were divided into 2 groups: the basic group (n=30) received calmirex (150mg 2 times a day during 10 days), amelotex (7.5 mg 2 times a day, 7 days) and kompligamB (1 ml once a day, 10 days). The control group (n=30) received only amelotex (7.5 mg 2 times a day, 7 days). The dynamics of the condition was assessed on a 10-point numerical rating scale (at rest, walking, palpation), the Oswestry functional status questionnaire (Oswestry Disability Index; ODI), as well as indicators of laboratory markers reflecting the severity of the inflammatory process (erythrocyte sedimentation rate, C-reactive protein (CRP)).

RESULTS

The severity of pain syndrome significantly decreased in both groups, to a greater extent in the basic group, and ODI indicators also significantly improved in the basic group. CRP indicators showed more pronounced changes in the basic group.

CONCLUSION

The complex therapy that affects all links in the formation of pain syndrome should be recommended to patients with LBP.

Keywords:

dorsopathy

low back pain

tolperison

Calmirex

meloxicam

Amelotex

vitamins of group B

Kompligam B

Authors:

Shavlovskaya O.A.

International University of Restorative Medicine», Moscow, Russia

SPIN RSCI: 5300-4282
ORCID: 0000-0003-3726-0730

Romanov I.D.

Sechenov First Moscow State Medical University (Sechenov University)

Received:

18.05.2020

Accepted:

26.05.2020

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