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Mironov M.B.

kafedra nevrologii i neĭrokhirurgii pediatricheskogo fakul'teta Rossiĭskogo gosudarstvennogo meditsinskogo universiteta;
Tsentr detskoĭ nevrologii i épilepsii, Moskva

Chebanenko N.V.

Nauchno-prakticheskiĭ tsentr detskoĭ psikhonevrologii Departamenta zdravookhraneniia Moskvy

Burd S.G.

Kafedra nevrologii i neĭrokhirurgii lechebnogo fakul'teta

Rubleva Yu.V.

Pirogov Russian National Research Medical University, Moscow

Tikhonova O.A.

Federal Center for Cerebrovascular Pathology and Stroke, Moscow, Russia

Krasilschikova T.M.

Pirogov Russian National Research Medical University, Moscow, Russia

Zykov V.P.

Rossiĭskaia meditsinskaia akademiia poslediplomnogo obrazovaniia, Moskva

Shamalov N.A.

Research Institute of cerebrovascular pathology and stroke of the Pirogov Russian national research medical University, Moscow, Russia

The effectiveness of antiepileptic therapy in patients with epileptic syndromes associated with myoclonic seizures

Authors:

Mironov M.B., Chebanenko N.V., Burd S.G., Rubleva Yu.V., Tikhonova O.A., Krasilschikova T.M., Zykov V.P., Shamalov N.A.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2020;120(4): 51‑59

DOI: 10.17116/jnevro202012004151

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To cite this article:

Mironov MB, Chebanenko NV, Burd SG, et al. . The effectiveness of antiepileptic therapy in patients with epileptic syndromes associated with myoclonic seizures. S.S. Korsakov Journal of Neurology and Psychiatry. 2020;120(4):51‑59. (In Russ.)
https://doi.org/10.17116/jnevro202012004151

 
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Objective. To evaluate the effectiveness of antiepileptic therapy of epileptic syndromes associated with myoclonic seizures. Material and methods. One hundred and three patients with epilepsy, in whom myoclonic seizures were identified during the observation, were examined. The observed myoclonic seizures entered the structure of 11 different epileptic syndromes. Results and Conclusion. Drug remission is achieved in 67% of patients, a decrease in the frequency of seizures by 50% or more was noted in 23,3%, the lack of effect in 9,7%. The effectiveness of antiepileptic therapy was significantly different in different groups of epileptic syndromes. The high effectiveness of antiepileptic therapy in the general group of patients in this study is mainly due to the prevalence of patients with juvenile myoclonic epilepsy, in which the highest percentage of remission was observed.

Keywords:

epilepsy
myoclonic seizures
antiepileptic therapy
video-EEG monitoring

Authors:

Mironov M.B.

kafedra nevrologii i neĭrokhirurgii pediatricheskogo fakul'teta Rossiĭskogo gosudarstvennogo meditsinskogo universiteta;
Tsentr detskoĭ nevrologii i épilepsii, Moskva

Chebanenko N.V.

Nauchno-prakticheskiĭ tsentr detskoĭ psikhonevrologii Departamenta zdravookhraneniia Moskvy

Burd S.G.

Kafedra nevrologii i neĭrokhirurgii lechebnogo fakul'teta

Rubleva Yu.V.

Pirogov Russian National Research Medical University, Moscow

Tikhonova O.A.

Federal Center for Cerebrovascular Pathology and Stroke, Moscow, Russia

Krasilschikova T.M.

Pirogov Russian National Research Medical University, Moscow, Russia

Zykov V.P.

Rossiĭskaia meditsinskaia akademiia poslediplomnogo obrazovaniia, Moskva

Shamalov N.A.

Research Institute of cerebrovascular pathology and stroke of the Pirogov Russian national research medical University, Moscow, Russia

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  2. ILAE commission report. Myoclonus and epilepsy in childhood. Epilepsia. 1997;38:11:1251-1254.
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