Cerebral insulin resistance: current concepts of the pathogenesis and possible therapeutic strategies

Esin R.G.; Khaĭrullin I.Kh.; Esin O.R.

doi:https://doi.org/10.17116/jnevro20181181192-95

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Abstract:

The review presents current concepts about the problem of cerebral insulin resistance (IR). It has now been established that cerebral IR plays a key role in the pathogenesis of degenerative and metabolic diseases of the brain. Based on literature data and own clinical experience, the authors recommend to use the standardized extract of ginkgo biloba EGb761 as a cellular protector, which increases insulin sensitivity of cells and reduces atherogenesis, in order to improve cognitive functions and quality of life in patients with diabetes mellitus.

Keywords:

insulin resistance

cognitive functions

diabetes mellitus

EGb761

Authors:

Esin R.G.

Kazanskaia gosudarstvennaia meditsinskaia akademiia

Khaĭrullin I.Kh.

GBUZ "Respublikanskaia klinicheskaia bol'nitsa #2" Minzdrava Respubliki Tatarstan, Kazan'

SPIN RSCI: 4122-6357
Scopus AuthorID: 56595561800
ResearcherID: F-2761-2017
ORCID: 0000-0003-0919-035X

Esin O.R.

Kazanskaia gosudarstvennaia meditsinskaia akademiia

SPIN RSCI: 8012-3620
Scopus AuthorID: 35738650000
ORCID: 0000-0003-4244-4446

Close metadata

References:

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