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Chutko L.S.

Institut mozga cheloveka RAN im. N.P. Bekhterevoĭ, Sankt-Peterburg;
Sankt-Peterburgskaia gosudarstvennaia pediatricheskaia meditsinskaia akademiia

Yakovenko E.A.

Institut mozga cheloveka RAN im. N.P. Bekhterevoĭ, Sankt-Peterburg

Surushkina S.Yu.

Institut mozga cheloveka RAN im. N.P. Bekhterevoĭ, Sankt-Peterburg;
Sankt-Peterburgskaia gosudarstvennaia pediatricheskaia meditsinskaia akademiia

Kryukova E.M.

Orenburg Regional Clinical Psychiatric Hospital №1, Orenburg, Russia

Palaieva S.V.

Orenburg Regional Clinical Psychiatric Hospital №1, Orenburg, Russia

The efficacy of cerebrolysin in the treatment of autism spectrum disorders

Authors:

Chutko L.S., Yakovenko E.A., Surushkina S.Yu., Kryukova E.M., Palaieva S.V.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2017;117(9): 71‑75

DOI: 10.17116/jnevro20171179171-75

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Table of contents

THE EFFICACY OF CEREBROLYSIN IN THE TREATMENT OF AUTISM SPECTRUM DISORDERS
THE EFFICACY OF CEREBROLYSIN IN THE TREATMENT OF AUTISM SPECTRUM DISORDERS

To cite this article:

Chutko LS, Yakovenko EA, Surushkina SYu, Kryukova EM, Palaieva SV. The efficacy of cerebrolysin in the treatment of autism spectrum disorders. S.S. Korsakov Journal of Neurology and Psychiatry. 2017;117(9):71‑75. (In Russ.)
https://doi.org/10.17116/jnevro20171179171-75

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)
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Abstract:

Objective. To evaluate clinical and neurophysiological changes in children with different variants of autism spectrum disorders during treatment with cerebrolysin. Material and methods. Forty-three children with autism spectrum disorders, aged 4—6 years, were included in the study. To assess the degree of autism, the quantitative scale of assessing the severity of child autism CARS («Childhood Autism Rating Scale») was used. A comparative analysis of the clinical picture of disease and data of the electroencephalographic examination in endogenous and exogenous (organic) variant of autism was made. Results and conclusion. In children with exogenous (organic) autism, the lower scores of autistic symptom on the CARS and a greater degree of functional immaturity of the cerebral cortex, according to electroencephalographic results, were found compared to children with endogenous autism. After treatment with cerebrolysin, 27 children (62.8%) showed signs of improvement. An improvement was noted in 13 children in with endogenous autism (56.5%) and in 14 children with organic autism (70.0%). CARS scores showed a more pronounced decrease in this indicator in a subgroup of children with organic autism.

Keywords:

autism spectrum disorders
treatment
cerebrolysin

Authors:

Chutko L.S.

Institut mozga cheloveka RAN im. N.P. Bekhterevoĭ, Sankt-Peterburg;
Sankt-Peterburgskaia gosudarstvennaia pediatricheskaia meditsinskaia akademiia

Yakovenko E.A.

Institut mozga cheloveka RAN im. N.P. Bekhterevoĭ, Sankt-Peterburg

Surushkina S.Yu.

Institut mozga cheloveka RAN im. N.P. Bekhterevoĭ, Sankt-Peterburg;
Sankt-Peterburgskaia gosudarstvennaia pediatricheskaia meditsinskaia akademiia

Kryukova E.M.

Orenburg Regional Clinical Psychiatric Hospital №1, Orenburg, Russia

Palaieva S.V.

Orenburg Regional Clinical Psychiatric Hospital №1, Orenburg, Russia

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References:

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