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Shipilova E.M.

Pirogov Russian National Research Medical University, Moscow, Russia

Zavadenko N.N.

Kafedra nevrologii i neĭrokhirurgii pediatricheskogo fakulteta Rossiĭskogo gosudarstvennogo meditsinskogo universiteta, Moskva

Nesterovsky Yu.E.

Pirogov Russian National Research Medical University, Moscow

Preventive treatment of tension headache in children and adolescents

Authors:

Shipilova E.M., Zavadenko N.N., Nesterovsky Yu.E.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2017;117(7): 36‑42

DOI: 10.17116/jnevro20171177136-42

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PREVENTIVE TREATMENT OF TENSION HEADACHE IN CHILDREN AND ADOLESCENTS
PREVENTIVE TREATMENT OF TENSION HEADACHE IN CHILDREN AND ADOLESCENTS

To cite this article:

Shipilova EM, Zavadenko NN, Nesterovsky YuE. Preventive treatment of tension headache in children and adolescents. S.S. Korsakov Journal of Neurology and Psychiatry. 2017;117(7):36‑42. (In Russ.)
https://doi.org/10.17116/jnevro20171177136-42

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)
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Abstract:

Objective. To assess the efficacy of noophen (γ-amino-β-phenylbutyric acid hydrochloride) in the preventive treatment of tension-type headache (TTH) in children and adolescents. Material and methods. The study included 30 patients with TTH, aged from 8 to 16 years, treated with noophen in dose of 15—20 mg/kg per day (2—3 times perorally) during 2 month. Before and during the treatment characteristics of headache, its influence on daily activities were assessed with HIT-6 and PedMIDAS, anxiety disorders were assessed with SCAS, the dynamics of sleep disturbances in children were evaluated. Results and conclusion. A significant decrease in the frequency, duration and intensity of TTH as well as positive changes in daily life activities and reduction of anxiety and sleep disorders manifestations, which are the risk factors for TTH, were demonstrated during the treatment with noophen. Starting from the first month of treatment, there was a significant decrease in the number of days completely lost because of headache and days with the reduced activity (a decrease in the productivity by >50%).

Keywords:

tension headache
children
adolescents
preventive treatment
noophen

Authors:

Shipilova E.M.

Pirogov Russian National Research Medical University, Moscow, Russia

Zavadenko N.N.

Kafedra nevrologii i neĭrokhirurgii pediatricheskogo fakulteta Rossiĭskogo gosudarstvennogo meditsinskogo universiteta, Moskva

Nesterovsky Yu.E.

Pirogov Russian National Research Medical University, Moscow

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References:

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