REM-sleep behavior disorder and sleepwalking in a patient with Parkinson’s disease and essential tremor

Close metadata

Recommended articles:

Melatonin for the regulation of sleep and other biological rhythms. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(5-2):8-13

Effects of slow-wave sleep fragmentation and rapid eye movement sleep fragmentation on melatonin secretion. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(5-2):26-32

Management of patients with insomnia and polymorbidity. A draft of the clinical guidelines. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(5-2):39-52

The interactions along the microbiota—gut—brain axis in the regulation of circadian rhythms, sleep mechanisms and disorders. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(5-2):79-86

Sleep disorders in patients with medication-overuse headache. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(5-2):93-98

Changes the level of differentiating growth factor — GDF 15 in patients with sleep apnea syndrome after aPAP-therapy: pilot study. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(5-2):118-124

The role of astrocytes, circadian rhythms and light pollution in the pathogenesis of Alzheimer’s disease. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(6):20-25

The association of single-nucleotide polymorphism rs6265 of the brain-derived neurotrophic factor gene with clinical features in Parkinson’s disease. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(7):82-88

Sarcopenia as a non-motor symptom of Parkinson’s disease. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(9):15-22

Problems in organizing neurosurgical care for patients with Parkinson’s disease in the Russian Federation. Burdenko's Journal of Neurosurgery. 2024;(3):5-13

REM-sleep behavior disorder (RBD), a form of parasomnia, is characterized by motor and/or speech activity during sleep corresponding to the dream content. RBD is currently considered as a marker of onset of neurodegenerative diseases (sinucleinopathies) and as a most specific early symptom of Parkinson’s disease (PD). The authors describe a clinical case of a patient with the combination of essential tremor, initial signs of PD and RBD. A polysomnographic study has confirmed clinical signs of RBD and determined the disturbances of sleep architecture: the increase in falling asleep, number of awakenings, wakefulness during sleep, the absence of deep slow-wave sleep. The particular features of the patient were essential tremor and sleep walking.

Keywords:

sleep

Parkinson’s disease

essential tremor

REM-sleep behavior disorder

sleep walking

Authors:

Nodel' M.R.

Kafedra nervnykh bolezneĭ lechebnogo fakul'teta Moskovskoĭ meditsinskoĭ akademii im. I.M. Sechenova

Tsenteradze S.L.

Kafedra nervnykh bolezneĭ Instituta professional'nogo obrazovaniia GBOU VPO "Pervyĭ Moskovskiĭ gosudarstvennyĭ meditsinskiĭ universitet im. I.M. Sechenova" Minzdrava Rossii, Moskva

Poluéktov M.G.

Kurs somnologii pri kafedre nervnykh bolezneĭ fakul'teta poslevuzovskogo professional'nogo obrazovaniia Moskovskoĭ meditsinskoĭ akademii im. I.M. Sechenova

List of references:

Arnulf I. REM sleep behavior disorder: motor manifestations and pathophysiology. Movement Disorders. 2012;27:677-689. https://doi.org/10.1002/mds.24957
Oudiette D, De Cock VC, Lavault S, Leu S, Vidailhet M, Arnulf I. Nonviolent elaborate behaviors may also occur in REM sleep behavior disorder. Neurology. 2009;72:551-557. https://doi.org/10.1212/01.wnl.0000341936.78678
Iranzo A, Molinuevo JL, Santamaria J, Serradell M, Martí MJ, Valldeoriola F, Tolosa E. Rapid-eye-movement sleep ehavior disorder as an early marker for a neurodegenerative disorder: a descriptive study. Lancet Neurol. 2006;5:572-577. https://doi.org/10.1016/S1474-4422(06)70476-8
Poluektov MG. Diagnostika i lechenie rasstroistv sna. M: MEDpress-inform; 2016. (In Russ.)
Krasakov IV, Litvinenko IV. REM sleep behavior disorder in Parkinsons disease — diagnosis and treatment. In: Parkinsons disease and movement disorders. Eds. Illarioshkin SN, Levin OS. M. 2014. (In Russ.)
Berg D, Postuma RB, Adler CH, Bloem BR, Chan P, Dubois B, Gasser T, Goetz CG, Halliday G, Joseph L, Lang AE, Liepelt-Scarfone I, Litvan I, Marek K, Obeso J, Oertel W, Olanow CW, Poewe W, Stern M, Deuschl G. MDS Research Criteria for Prodromal Parkinsons Disease. Movement Disorders. 2015;30(12):1600-1609. https://doi.org/10.1002/mds.26431
Liashenko EA, Poluektov MG, Levin OS. REM sleep behavior disorders in Parkinson’s disease. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 2014;114:6(2):73-79. (In Russ.)
Nodel MR, Ukraintseva YuV, Yakhno NN. Rapid-eye-movement sleep behavior disorder in Parkinson’s disease. Neurologicheskiy zhurnal. 2015;6:28-34. (In Russ.)
Amosova NA, Smolentseva IG, Guseinova PM, Maslyuk OA, Gavrilov EL. Sleep disorders in the early stage of Parkinson’s disease in untreated patients. Zhurnal neurologii I psikhiatrii im. S.S. Korsakova. 2016;116(6):77-81. (In Russ.)
Soh Sze-Ee, Morris ME, McGinley JL. Determinants of health-related quality of life in Parkinson’s disease: a systematic review. Parkinsonism Relat Disord. 2011;17:1-9. https://doi.org/10.1016/j.parkreldis.2010.08.012
Nodel МR. The impact of neuropsychiatric symptoms on quality of life of patients with Parkinsons disease. Neurologicheskiy zhurnal. 2015;1:20-25. (In Russ.) https://doi.org/10.18821/1560-9545-2015-20-1-20-27
Iranzo A, Tolosa E. REM sleep behavior disorder in Parkinson’s disease. In Non-motor symptoms of Parkinsons Disease. Eds. KR Chaudhury, E Tolosa, A Shapira, W Poewe. Oxford University Press; 2009;205-213.
Berry RB, Budhiraja R, Gottlieb DJ, Gozal D, Iber C, Kapur VK, Marcus CL, Mehra R, Parthasarathy S, Quan SF, Redline S, Strohl KP, Davidson Ward SL, Tangredi MM. Rules for scoring respiratory events in sleep: Update of the 2007 AASM manual for the scoring of sleep and associated events. J Clin Sleep Med. 2012;8:597-619. https://doi.org/10.5664/jcsm.2172
Postuma RB, Berg D, Stern M, Poewe W, Olanow CW, Oertel W, Obeso J, Marek K, Litvan I, Lang AE, Halliday G, Goetz CG, Gasser T, Dubois B, Chan P, Bloem BR, Adler CH, Deuschl G. MDS Clinical Diagnostic Criteria for Parkinsons Disease. Movement Disorders. 2015;30(12):1591-1599. https://doi.org/10.1002/mds.26424
Ferreira JJ, Katzenschlager R, Bloem BR, Bonuccelli U, Burn D, Deuschl G, Dietrichs E, Fabbrini G, Friedman A, Kanovsky P, Kostic V, Nieuwboer A, Odin P, Poewe W, Rascol O, Sampaio C, Schüpbach M, Tolosa E, Trenkwalder C, Schapira A, Berardelli A, Oertel WH. Summary of the recommendations of the EFNS/MDS-ES reviewon therapeutic management of Parkinson’s disease. European Journal of Neurology. 2013;20:5-15.
Zalalova ZA. Tremor phenotypes in Parkinsons disease. In: Parkinsons disease and movement disorders. Eds. Illarioshkin S.N., Levin O.S. M. 2014. (In Russ.)
Feketa R, Jankovic J. Revisiting the relationship between essential tremor and Parkinson’s disease. Mov Disord. 2011;26:391-398. https://doi.org/10.1002/mds.23512
Spanaki C, Plaitakis A. Essential tremor in Parkinson’s disease kindreds from a population of similar genetic background. Mov Disord. 2009;24(11):1662-1668. https://doi.org/10.1002/mds.22655
Chao YX, Ng EY, Foo JN, Liu J, Zhao Y, Tan EK. Mitochondrial serine protease HTRA2 gene mutation in Asians with coexistent essential tremor and Parkinson disease. Neurogenetics. 2015;16(3):241-242. Epub 2015 Mar 20. https://doi.org/10.1007/s10048-015-0443-3
Kwon KY, Lee HM, Lee SM, Kang SH, Koh SB. Comparison of motor and non-motor features between essential tremor and tremor dominant Parkinson’s disease. J Neurol Sci. 2016;361:34-38. https://doi.org/10.1016/j.jns.2015.12.016
Golubev VL, Yahno NN. Night sleep in Parkinsonism. In: Sleep and their disturbances. М. 1972. (In Russ.)
Nodel MR, Rusakova IM, Yakhno NN. Clinic assessment of sleep and wakefulness disturbances in Parkinson’s disease. Neurologicheskiy zhurnal. 2010;2:19-25. (In Russ.)
Nodel MR, Yakhno NN, Ukraintseva UV, Dorochov VB. Insomnia in Parkinsons disease and their impact on patients quality of life. Neurologicheskiy zhurnal. 2014;4(19):19-27. (In Russ.)
Joy SP, Sinha S, Pal PK, Panda S, Philip M, Taly AB. Alterations in Polysomnographic (PSG) profile in drug-naïve Parkinson’s disease. Ann Indian Acad Neurol. 2014;17(3):287-291. https://doi.org/10.4103/0972-2327.138501
Kovalzon VM, Ugrumov MV, Pronina TS, Dorokhov VB, Manolov AI, Dolgikh VV, Ukraintseva YV, Moiseenko LS, Poluektov MG, Kalinkin AL. Early Stages of Parkinson’s disease: Comparative Characteristics of Sleep-Wakefulness Cycle in Patients and Model Animal. Fiziologia Cheloveka. 2015;41(6):114-148. (In Russ.)
Di Fabio N, Poryazova R, Oberholzer M, Baumann CR, Bassetti CL. Sleepwalking, REM sleep behavior disorder and overlap parasomnia in patients with Parkinson’s disease. Eur Neurol. 2013;70(5-6):297-303. https://doi.org/10.1159/000353378
Ylikoski A, Martikainen K, Partinen M. Parasomnias and isolated sleep symptoms in Parkinson’s disease: a questionnaire study on 661 patients. J Neurol Sci. 2014;346(1-2):204-208. https://doi.org/10.1016/j.jns.2014.08.025
Postuma RB, Bertrand JA, Montplaisir J, Desjardins C, Vendette M, Rios Romenets S, Panisset M, Gagnon JF. Rapid eye movement sleep behavior disorder and risk of dementia in Parkinsons Disease. Movement Disorders. 2012;6:720-726.
Litvinenko IV, Krasakov IV, Tichomirova OV. Impairments of sleep in Parkinsons disease patients with of dementia. Zurnal neurologii i psikhiatrii im. S.S. Korsakova. 2011;111(9):37-42. (In Russ.)
Erro R, Bhatia K, Tinazzi M. The following neutoleptic exposure: a double-hit hypothesis? Mov Dis. 2015;30:780-785.
Nodel MR. Drug-induced Parkinsonism: the possibility of the risk minimization. Nervnii bolezni. 2015;3:16-19. (In Russ.)
Nodel MR. Modern possibilities of treatment of sleep disorders in patients with Parkinson’s disease. Nevrologia. Neuropsichiatria. Psychosomatica. 2013(2):30-34. (In Russ.)
Di Giacopo R, Fasano A, Quaranta D, Della Marca G, Bove F, Bentivoglio AR. Rivastigmine as alternative treatment for refractory REM behavior disorder in Parkinson disease. Mov Dis. 2012;4:559-561.

Close metadata