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Lavrick S.Yu.

Irkutsk State Medical Academy of Postgraduate Education – Branch of the Medical Academy for Continuous Professional Education

Borisov A.S.

Irkutsk State Medical University

Shprakh V.V.

Irkutsk State Medical Academy of Postgraduate Education — branch of the Russian Medical Academy of Continuous Professional Education

Cellex in the therapy of patients with complex and central apnea in the early recovery period of ischemic stroke

Authors:

Lavrick S.Yu., Borisov A.S., Shprakh V.V.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2021;121(3‑2): 29‑32

DOI: 10.17116/jnevro202112103229

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Table of contents

CELLEX IN THE THERAPY OF PATIENTS WITH COMPLEX AND CENTRAL APNEA IN THE EARLY RECOVERY PERIOD OF ISCHEMIC STROKE
CELLEX IN THE THERAPY OF PATIENTS WITH COMPLEX AND CENTRAL APNEA IN THE EARLY RECOVERY PERIOD OF ISCHEMIC STROKE

To cite this article:

Lavrick SYu, Borisov AS, Shprakh VV. Cellex in the therapy of patients with complex and central apnea in the early recovery period of ischemic stroke. S.S. Korsakov Journal of Neurology and Psychiatry. 2021;121(3‑2):29‑32. (In Russ.)
https://doi.org/10.17116/jnevro202112103229

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова. Спецвыпуски (S.S. Korsakov Journal of Neurology and Psychiatry (special issues))
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Abstract:

A variety of structural and functional post-stroke disturbances demands an integrated clinical/diagnostic approach. Persistent hypoxemia due to disturbance of a saturation of blood oxygen in sleep can decrease the effectiveness of neurorehabilitation. In some cases of sleep apnea, the efficiency of continuous positive airway pressure therapy is insufficient and it should be combined with course neuroprotective therapy. Modern approaches to neuroprotective and neuroreparative therapy are considered as the independent direction for treatment of the central sleep apnea syndromes in patients with stroke consequences that is obviously important aspect of secondary prevention of a stroke.

Keywords:

stroke rehabilitation
sleep apnea
cardiorespiratory monitoring
neuroprotective therapy
cellex

Authors:

Lavrick S.Yu.

Irkutsk State Medical Academy of Postgraduate Education – Branch of the Medical Academy for Continuous Professional Education

Borisov A.S.

Irkutsk State Medical University

Shprakh V.V.

Irkutsk State Medical Academy of Postgraduate Education — branch of the Russian Medical Academy of Continuous Professional Education

Received:

12.02.2021

Accepted:

15.02.2021

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References:

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  5. Birkbak J, Clark AJ, Rod NH. The effect of sleep disordered breathing on the outcome of stroke and transient ischemic attack: a systematic review. J Clin Sleep Med. 2014;10(1):103-108.  https://doi.org/10.5664/jcsm.3376
  6. Parra O, Sanchez-Armengol A, Capote F, et al. Efficacy of continuous positive airway pressure treatment on 5-year survival in patients with ischaemic stroke and obstructive sleep apnea: a randomized controlled trial. J Sleep Res. 2015;24(1):47-53.  https://doi.org/10.1111/jsr.12181
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  8. Pearce SC, Stolwyk RJ, New PW, Anderson C. Sleep disturbance and deficits of sustained attention following stroke. J Clin Exp Neuropsychol. 2016;38(1):1-11.  https://doi.org/10.1080/13803395.2015.1078295
  9. Cooksey JA, Balachandran JS. Portable monitoring for the diagnosis of OSA. Chest. 2016;149(4):1074-1081. https://doi.org/10.1378/chest.15-1076
  10. Tselleks (Cellex) [Internet]. Registr lekarstvennykh sredstv Rossii (RLS): Entsiklopediya lekarstv i tovarov aptechnogo assortimenta; Nov 16, 2020. Accessed Feb 2, 2021. (In Russ.). https://rlsnet.ru/tn_index_id_49945.htm
  11. Palman AD. Complex sleep apnea syndrome. S.S. Korsakov Journal of Neurology and Psychiatry. 2017;117(4-2):60-66. (In Russ.). https://doi.org/10.17116/jnevro20171174260-66
  12. Yu J, Zhou Z, McEvoy RD, et al. Association of Positive Airway Pressure With Cardiovascular Events and Death in Adults With Sleep Apnea: A Systematic Review and Meta-analysis. JAMA. 2017;318(2):156-166.  https://doi.org/10.1001/jama.2017.7967
  13. Gaponenko IA, Bakhareva EV, Zolotareva ZM, et al. The experience of using cellex in treatment of patients with acute ischemic stroke. S.S. Korsakov Journal of Neurology and Psychiatry. 2018;118(4):43-47. (In Russ.). https://doi.org/10.17116/jnevro20181184143-47
  14. Kulesh AA, Shestakov VV. Post-stroke cognitive impairment and the possibility of treatment with cellex. S.S. Korsakov Journal of Neurology and Psychiatry. 2016;116(5):38-42. (In Russ.). https://doi.org/10.1007/s11055-017-0490-3
  15. Volodeeva EA, Samarina SYu, Glotova ME, Kurtin AN. Effectiveness of complex rehabilitation in post-stroke patients treated with cellex. S.S. Korsakov Journal of Neurology and Psychiatry. 2020;120(8):34-41. (In Russ.). https://doi.org/10.17116/jnevro202012008134
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