Alcohol withdrawal syndrome dynamics during treatment with nooclerin (deanoli aceglumas)

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Agibalova T.V.

Natsional'nyĭ nauchnyĭ tsentr narkologii Minzdravsotsrazvitiia Rossii

Buzik O.Zh.

GKUZ Moskovskiĭ nauchno-prakticheskiĭ tsentr narkologii Departamenta zdravookhraneniia Moskvy, Moskva

Rychkova O.V.

FGBU "Natsional'nyĭ nauchnyĭ tsentr narkologii" Minzdrava RF, Moskva

Smyshlyaev A.V.

Central Scientific Research Institute of Health Organization and Informatization, Moscow, Russia

Rumbesht V.V.

Belgorod State National Research University, Belgorod, Russia

Alcohol withdrawal syndrome dynamics during treatment with nooclerin (deanoli aceglumas)

Authors:

Agibalova T.V., Buzik O.Zh., Rychkova O.V., Smyshlyaev A.V., Rumbesht V.V.

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Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2018;118(1‑2): 45‑51

DOI: 10.17116/jnevro20181181245-51

Views: 2363

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To cite this article:

Agibalova TV, Buzik OZh, Rychkova OV, Smyshlyaev AV, Rumbesht VV. Alcohol withdrawal syndrome dynamics during treatment with nooclerin (deanoli aceglumas). S.S. Korsakov Journal of Neurology and Psychiatry. 2018;118(1‑2):45‑51. (In Russ.)
https://doi.org/10.17116/jnevro20181181245-51

Подписка 2025-2 (S.S. Korsakov Journal of Neurology and Psychiatry (special issues))

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Objective. To study the efficacy of nooclerin (deanoli aceglumas) in alcohol withdrawal syndrome assessed by clinical and biochemical characteristics. Material and methods. A multicenter, open, randomized, comparative study of nooclerin in the complex treatment of alcohol withdrawal syndrome included 90 patients. The patients were randomized into nooclerin group (n=55) and control group (n=35). Results and сonclusion. Nooclerin reduced alcohol withdrawal symptoms more significantly throughout the whole study period. There were significant between-group differences on the Clinical Institute Withdrawal Assessment of Alcohol Scale (CIWA-Ar) and the Multidimensional Fatigue Inventory (МFI-20). However, patients exhibited no excessive activity. No adverse side-effects were observed.

Keywords:

alcohol withdrawal syndrome

nooclerin (deanoli aceglumas)

alcohol dependence

Authors:

Agibalova T.V.

Natsional'nyĭ nauchnyĭ tsentr narkologii Minzdravsotsrazvitiia Rossii

Buzik O.Zh.

GKUZ Moskovskiĭ nauchno-prakticheskiĭ tsentr narkologii Departamenta zdravookhraneniia Moskvy, Moskva

Rychkova O.V.

FGBU "Natsional'nyĭ nauchnyĭ tsentr narkologii" Minzdrava RF, Moskva

Smyshlyaev A.V.

Central Scientific Research Institute of Health Organization and Informatization, Moscow, Russia

Rumbesht V.V.

Belgorod State National Research University, Belgorod, Russia

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