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Vasenina E.E.

Rossiĭskaia meditsinskaia akademiia poslediplomnogo obrazovaniia, Moskva

Levin O.S.

Rossiĭskaia meditsinskaia akademiia poslediplomnogo obrazovaniia

Sonin A.G.

Merz, Moscow, Russia

Modern trends in epidemiology of dementia and management of patients with cognitive impairment

Authors:

Vasenina E.E., Levin O.S., Sonin A.G.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2017;117(6‑2): 87‑95

DOI: 10.17116/jnevro20171176287-95

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Table of contents

MODERN TRENDS IN EPIDEMIOLOGY OF DEMENTIA AND MANAGEMENT OF PATIENTS WITH COGNITIVE IMPAIRMENT
MODERN TRENDS IN EPIDEMIOLOGY OF DEMENTIA AND MANAGEMENT OF PATIENTS WITH COGNITIVE IMPAIRMENT

To cite this article:

Vasenina EE, Levin OS, Sonin AG. Modern trends in epidemiology of dementia and management of patients with cognitive impairment. S.S. Korsakov Journal of Neurology and Psychiatry. 2017;117(6‑2):87‑95. (In Russ.)
https://doi.org/10.17116/jnevro20171176287-95

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова. Спецвыпуски (S.S. Korsakov Journal of Neurology and Psychiatry (special issues))
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Abstract:

Dementia is an important medical problem with the prevalence and significance growing year after year. Improvement of diagnostic methods facilitates early diagnosis and treatment. This year marks the 20th anniversary of memantine, one of the basic anti-dementia drugs, registration in Russia. It provided conditions for more efficient care of patients with dementia and development of memory clinics in Moscow and major regions of Russia used modern investigation technology and neuropsychological testing. Many multi-central studies involving 1250 patients with cognitive impairment were conducted A great number of educational activities, social projects that helped to increase awareness of dementia issues in medical community as well as society in general were implemented. Total screening programs for identification of cognitive impairment are being introduced, psychological support programs for caregivers of dementia patients are being implemented.

Keywords:

dementia
Alzheimer disease
acatinol
memantine

Authors:

Vasenina E.E.

Rossiĭskaia meditsinskaia akademiia poslediplomnogo obrazovaniia, Moskva

Levin O.S.

Rossiĭskaia meditsinskaia akademiia poslediplomnogo obrazovaniia

Sonin A.G.

Merz, Moscow, Russia

Close metadata

References:

  1. Levin OS, Vasenina EE. Twenty-five years of the amyloid hypothesis of alzheimer disease: advances, failures and new perspectives. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 2016;116:6(2):3-12. (In Russ.). https://doi.org/10.17116/jnevro2016116623-9
  2. Gutorova DA, Vasenina EE, Levin OS. Screening of cognitive impairment in the old and old-old population with the 3-CT scale. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 2016;116:6(2):35. (In Russ.). https://doi.org/10.17116/jnevro20161166235-40
  3. Vasenina EE, Levin OS. Adherence to therapy in patients with dementia. Modern therapy in psychiatry and neurology. 2016;4:4-8. (In Russ.).
  4. Chen HS, Pellegrini JW, Aggarwal SK, Lei SZ, Warach S, Jensen FE, Lipton SA. Open-channel block of N-methyl-D-aspartate (NMDA) responses by memantine: therapeutic advantage against NMDA receptor-mediated neurotoxicity. Journal Neuroscience. 1992;12(11):4427-4436.
  5. Makotrova TA, Trusova NA, Shrader NI, Levin OS. Neuroprotective potential of akatinol-memantine in ischemic stroke. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 2013;113(7-2):82-85. (In Russ.).
  6. Sheik Hosenbocus, Raj Chahal. Memantine: A Review of Possible Uses in Child and Adolescent Psychiatry. J Can Acad Child Adolesc Psychiatry. 2013;22:2.
  7. Levin O, Yunishchenko N, Dudarova M. Efficacy of Akatinol Memantine in Moderate Cognitive Impairments. Neuroscience and Behavioral Physiology. 2010;40(8):926-933. https://doi.org/10.1007/s11055-010-9347-8
  8. Uspenskaya O, Yakhno N. PO22-TH-04 Memantine hampers the progression of cognitive dysfunction and conversion to dementia in amnestic MCI patients. Journal of the Neurological Sciences. 2009;285:275. https://doi.org/10.1016/s0022-510x(09)71046-9
  9. Yakchno NN, Preobrazhenskaya IS, Zakharov VV, Mkhitaryan EA. fficacy of Akatinol memantine in petients with non-dementia cognitive impairments. Results of multicenter study. The Journal of Nervous Diseases. 2010;15(2):52-58. (In Russ.).
  10. Voznesenskaya TG. Akatinol in the treatment of noncognitive neuropsychological disorders in neurogeriatric diseases. Neurology, Neuropsychiatry, Psychosomatics. 2012;4(2):11-17. (In Russ.). https://doi.org/10.14412/2074-2711-2012-2503
  11. Gavrilova S, Kalyn Y, Gerasimov N, Gantman M. PW01-78 — Pharmacoeconomic aspects of dementia therapy. European Psychiatry. 2010;25:1494. https://doi.org/10.1016/s0924-9338(10)71477-2
  12. Bolshakov YuA, Merkel VA, Solovyova NV. Acatinol (Memantine) in the in-patient treatment of moderate and severe dementia. Social and clinical psychiatry. 2009;19(1):61-64. (In Russ.).
  13. Lyubov EB. Pharmacoeconomic prognosis for long-term treatment of alzheimer patients with akatinol (memantine). Social and clinical psychiatry. 2010;20(1):43-51. (In Russ.).
  14. Gudkova AA, Sorokina IB, Iakovlev AA, Guliaeva NV, Gekht AB. Akatinol memantine in patients with vascular cognitive disorders. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 2010;110(12):37-40. (In Russ.).
  15. Khatkova SE. Use of akatinol memantin in poststroke dementia. Clinical gerontology. 2008;14(8):19-21. (In Russ.).
  16. Gusev EI, Avakyan GN, Bogolepova AN, Katunina EA. Efficacy of akatinol memntine in patients with vascular dementia and Parkinson disease dementia. The Journal of Nervous Diseases. 2007;1:15-20. (In Russ.).
  17. Levin OS, Batukaeva LA. Efficacy of memantine in Parkinson’s disease with dementia. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 2008;108:12:16-23. (In Russ.).
  18. Levin O, Batukaeva L, Smolentseva I, Amosova N. Efficacy and safety of memantine in Lewy body dementia. Neuroscience and Behavioral Physiology. 2009;39(6):597-604. https://doi.org/10.1007/s11055-009-9167-x
  19. Puzin MN, Krivonos ОV, Kozhevnikova ZhV. Akatinol memantine in the therapy of cognitive disorders in Parkinson’s disease. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 2007;107(1):26-30. (In Russ.).
  20. Litvinenko I, Odinak M, Mogil’naya V, Perstnev S. Use of Memantine (akatinol) for the Correction of Cognitive Impairments in Parkinson’s Disease Complicated by Dementia. Neuroscience and Behavioral Physiology. 2009;40(2):149-155. https://doi.org/10.1007/s11055-009-9244-1
  21. Lukyanuk EV, Malyukova NG, Shklovsky VM, Sayadyan KHS. The use of Akatinol memantine in the residual phase of stroke. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 2010;110:12(2):28-33. (In Russ.).
  22. Litvinenko IV, Emelin AIu, Vorob’ev SV, Lobzin VIu. Clinical features of the formation and possibilities of treatment of posttraumatic cognitive disturbances. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 2010;110(12):60-66. (In Russ.).
  23. Solomatin YuV, Kurbatova VV, Serdyuk IE, Logvinov YuI, Shamokhova MM, Burd SG, Lebedeva AV. Experience with the drug memantine in patients with focal epilepsy and cognitive impairment. Epilepsia and paroxyzmal conditions. 2013;5(2):11-17. (In Russ.).
  24. Seleznyova N, Kolykhalov I, Kalyn Y, Zharikov G, Mikhailova N, Gavrilova S. P-8-18 Akatinol memantine in Alzheimer’s disease. European Neuropsychopharmacology. 1998;5(3):385. https://doi.org/10.1016/0924-977x(95)90698-d
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