The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-4329
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2026
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Pelishenko T.G.

Central State Medical Academy

Gusakova E.V.

Central State Medical Academy

Ivanova I.I.

Central State Medical Academy of the Presidential Administration

Filatova E.V.

Central State Medical Academy of the Presidential Administration

Nagornev S.N.

Central State Medical Academy

Koryagin F.N.

Central State Medical Academy

Therapeutic physical factors in comprehensive rehabilitation for patients with polypous rhinosinusitis (Handbook, 2025)

Authors:

Pelishenko T.G., Gusakova E.V., Ivanova I.I., Filatova E.V., Nagornev S.N., Koryagin F.N.

More about the authors

Journal: Regenerative Biotechnologies, Preventive, Digital and Predictive Medicine. 2025;2(4): 67‑90

DOI: 10.17116/rbpdpm2025204167

Read: 289 times

Buy for 300₽
Contact the author
Table of contents

THERAPEUTIC PHYSICAL FACTORS IN COMPREHENSIVE REHABILITATION FOR PATIENTS WITH POLYPOUS RHINOSINUSITIS (HANDBOOK, 2025)
THERAPEUTIC PHYSICAL FACTORS IN COMPREHENSIVE REHABILITATION FOR PATIENTS WITH POLYPOUS RHINOSINUSITIS (HANDBOOK, 2025)

To cite this article:

Pelishenko TG, Gusakova EV, Ivanova II, Filatova EV, Nagornev SN, Koryagin FN. Therapeutic physical factors in comprehensive rehabilitation for patients with polypous rhinosinusitis (Handbook, 2025). Regenerative Biotechnologies, Preventive, Digital and Predictive Medicine. 2025;2(4):67‑90. (In Russ.)
https://doi.org/10.17116/rbpdpm2025204167

 
Подписка 2026 Восстановительные биотехнологии, профилактическая, цифровая и предиктивная медицина (Regenerative Biotechnologies, Preventive, Digital and Predictive Medicine)
МСФ на ЯМ
Использование инфографики авторами научных работ
Recommended articles:
Syne­rgistic effi­ciency of preformed physical factors and dupi­lumab in the treatment of poly­pous rhinosinusitis. Rege­nerative Biotechnologies, Preventive, Digi­tal and Predictive Medi­cine. 2025;(2):16-23
Rela­tionship between oxidative stress patterns and proinflammatory cyto­kines in patients with poly­pous rhinosinusitis under the course of therapeutic physical factors. Rege­nerative Biotechnologies, Preventive, Digi­tal and Predictive Medi­cine. 2025;(2):42-49
Rege­nerative capa­bilities of platelet-rich plasma in different age groups. Piro­gov Russian Journal of Surgery. 2025;(5):36-43
Diagnosis of pathological and adaptive bala­nce changes in Parkinson’s disease to select a reha­bilitation program. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(4):88-94
Factors of health formation in disa­bled children with congenital cleft lip and/or palate. Stomatology. 2025;(2):30-36
Rela­tionship of the professional characteristics and the orga­nization of the mid-level medi­cal personnel reha­bilitation depa­rtments acti­vity to the health psychophysical indi­cators of children with disa­bilities. Russian Journal of Preventive Medi­cine. 2025;(7):28-35
Reha­bilitation of persons with primary orga­nic mental diso­rders complicated by alco­holism in middle and elde­rly age. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(7):55-63
Arti­ficial inte­lligence in comprehensive reha­bilitation of people with disa­bilities. (Literature review). Problems of Balneology, Physiotherapy and Exercise Therapy. 2025;(3):54-61
Evaluation of the effe­ctiveness of inte­nsive medi­cal reha­bilitation in MS patients through the prism of functional tests and serum neurofilaments. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(7-2):79-83
The role of perioperative reha­bilitation of patients in surgical treatment of pelvic and lower extremity bone tumors with endo­prosthesis. P.A. Herzen Journal of Onco­logy. 2025;(4):22-28
Abstract:

This handbook focuses on therapeutic physical factors (general low-frequency magnetic therapy, low-intensity laser therapy, and their combination) in comprehensive rehabilitation of patients with polypous rhinosinusitis. These methods are designed to improve the effectiveness of rehabilitation for patients with moderate-to-severe polypous rhinosinusitis and uncontrolled progression based on biological therapy (dupilumab) and supplemented by a course of comprehensive therapeutic physical factors. The handbook is intended for physiotherapists and spa therapists, otolaryngologists, and rehabilitation specialists and can be used in medical and preventive care and health resort facilities.

Keywords:

polypous rhinosinusitis
magnetotherapy
laser therapy
biological therapy
personalized medicine
rehabilitation

Authors:

Pelishenko T.G.

Central State Medical Academy

Gusakova E.V.

Central State Medical Academy

Ivanova I.I.

Central State Medical Academy of the Presidential Administration

Filatova E.V.

Central State Medical Academy of the Presidential Administration

Nagornev S.N.

Central State Medical Academy

Koryagin F.N.

Central State Medical Academy

Received:

13.09.2025

Accepted:

10.10.2025

Close metadata

References:

  1. Klinicheskie rekomendacii: Polipozny’j rinosinusit. M., 2016. Accessed November 30, 2025. (In Russ.). https://glav-otolar.ru/assets/images/docs/clinical-recomendations/%D0%9A%D0%A0316%20%20Polipoznyj%20rinosinusit1.pdf?ysclid=mj2pmytiuk112713106
  2. EXPO 2020 Clinical Guidelines: Are all the questions answered? Farmakologiya i farmakoterapiya. 2021;1:44-46. (In Russ.).
  3. Klinicheskie rekomendacii: Polipozny’j rinosinusit. M., 2024. Accessed November 30, 2025. (In Russ.). https://diseases.medelement.com/disease/polipoznyj-rinosinusit-kr-rf-2024/18483
  4. Aref’eva NA, Medvedev YuA, Fazly’eva RM. Immunologiya, immunopatologiya i problemy’ immunoterapii v rinologii. Ufa, 1997. (In Russ.).
  5. Budkovaya MA, Dvoryanchikov VV, Ryazantsev SV, Maltseva GS. Chronic Rhinosinusitis with Nasal Polyps: from Radicalism to Targeting the Mechanisms of Inflammation. E’ffektivnaya farmakoterapiya. 2021;17(18):22-25. (In Russ.). https://doi.org/10.33978/2307-3586-2021-17-18-22-25
  6. Moiseeva YuP, Piskunov GZ. Molecular and genetic aspects of polypous rhinosinusitis. Rossijskaya rinologiya. 2020;28(1):26-31. (In Russ.).
  7. Chronic polypous rhinosinusitis: a revolution in treatment approaches. E’ffektivnaya farmakoterapiya. 2020;16(37):36-43. (In Russ.).
  8. Buyavy’x AG. Fizicheskaya terapiya v otorinolaringologicheskoj praktike. Prakticheskoe rukovodstvo. M.: MIA; 2019. (In Russ.).
  9. Gerasimenko MYu, Zaitseva TN, Evstigneeva IS. Physiotherapy of ear, throat, and nose diseases. Fizioterapevt. 2020;6:66-79. (In Russ.).
  10. Vorozhczov AA, Moskvin SV, Zenger VG, Nasedkin AN. Lazerny’e texnologii v kompleksnom lechenii bol’ny’x xronicheskim polipozny’m rinosinusitom. Tver’: Izd-vo «Triada»; 2005. (In Russ.).
  11. Pelishenko TG, Kruglova LS, Nagornev SN. Complex use of therapeutic physical factors in the conduct of medical rehabilitation of patients with polypous rhinosinusitis associated with bronchial asthma. Russian Journal of Environmental and Rehabilitation Medicine. Rossijskij zhurnal e’kologicheskoj i vosstanovitel’noj mediciny’. 2023;4:32-39. (In Russ.).
  12. Pelishenko TG, Kruglova LS, Nagornev SN, Boyarintsev VV. Evaluation of the results of complex medical rehabilitation of patients with polyposis rhinosinusitis in the long-term period. Fizioterapiya, bal’neologiya i reabilitaciya. 2023;22(2):87-96. (In Russ.). https://doi.org/10.17816/569340
  13. Fokkens WJ, Viskens AS, Backer V, Conti D, De Corso E, Gevaert P, Scadding GK, Wagemann M, Bernal-Sprekelsen M, Chaker A, Heffler E, Han JK, Van Staeyen E, Hopkins C, Mullol J, Peters A, Reitsma S, Senior BA, Hellings PW. EPOS/EUFOREA update on indication and evaluation of Biologics in Chronic Rhinosinusitis with Nasal Polyps 2023. Rhinology. 2023;61(3):194-202.  https://doi.org/10.4193/Rhin22.489
  14. Fokkens WJ, Lund V, Bachert C, Mullol J, Bjermer L, Bousquet J, Canonica GW, Deneyer L, Desrosiers M, Diamant Z, Han J, Heffler E, Hopkins C, Jankowski R, Joos G, Knill A, Lee J, Lee SE, Mariën G, Pugin B, Senior B, Seys SF, Hellings PW. EUFOREA consensus on biologics for CRSwNP with or without asthma. Allergy. 2019;74(12): 2312-2319. https://doi.org/10.1111/all.13875
  15. Fokkens WJ, Lund VJ, Hopkins C, Hellings PW, Kern R, Reitsma S, Toppila-Salmi S, Bernal-Sprekelsen M, Mullol J, Alobid I, Terezinha Anselmo-Lima W, Bachert C, Baroody F, von Buchwald C, Cervin A, Cohen N, Constantinidis J, De Gabory L, Desrosiers M, Diamant Z, Douglas RG, Gevaert PH, Hafner A, Harvey RJ, Joos GF, Kalogjera L, Knill A, Kocks JH, Landis BN, Limpens J, Lebeer S, Lourenco O, Meco C, Matricardi PM, O’Mahony L, Philpott CM, Ryan D, Schlosser R, Senior B, Smith TL, Teeling T, Tomazic PV, Wang DY, Wang D, Zhang L, Agius AM, Ahlstrom-Emanuelsson C, Alabri R, Albu S, Alhabash S, Aleksic A, Aloulah M, Al-Qudah M, Alsaleh S, Baban MA, Baudoin T, Balvers T, Battaglia P, Bedoya JD, Beule A, Bofares KM, Braverman I, Brozek-Madry E, Richard B, Callejas C, Carrie S, Caulley L, Chussi D, de Corso E, Coste A, El Hadi U, Elfarouk A, Eloy PH, Farrokhi S, Felisati G, Ferrari MD, Fishchuk R, Grayson W, Goncalves PM, Grdinic B, Grgic V, Hamizan AW, Heinichen JV, Husain S, Ping TI, Ivaska J, Jakimovska F, Jovancevic L, Kakande E, Kamel R, Karpischenko S, Kariyawasam HH, Kawauchi H, Kjeldsen A, Klimek L, Krzeski A, Kopacheva Barsova G, Kim SW, Lal D, Letort JJ, Lopatin A, Mahdjoubi A, Mesbahi A, Netkovski J, Nyenbue Tshipukane D, Obando-Valverde A, Okano M, Onerci M, Ong YK, Orlandi R, Otori N, Ouennoughy K, Ozkan M, Peric A, Plzak J, Prokopakis E, Prepageran N, Psaltis A, Pugin B, Raftopulos M, Rombaux P, Riechelmann H, Sahtout S, Sarafoleanu CC, Searyoh K, Rhee CS, Shi J, Shkoukani M, Shukuryan AK, Sicak M, Smyth D, Sindvongs K, Soklic Kosak T, Stjarne P, Sutikno B, Steinsvag S, Tantilipikorn P, Thanaviratananich S, Tran T, Urbancic J, Valiulius A, Vasquez de Aparicio C, Vicheva D, Virkkula PM, Vicente G, Voegels R, Wagenmann MM, Wardani RS, Welge-Lussen A, Witterick I, Wright E, Zabolotniy D, Zsolt B, Zwetsloot CP. European Position Paper on Rhinosinusitis and Nasal Polyps 2020. Rhinology. 2020;58(Suppl S29):1-464.  https://doi.org/10.4193/Rhin20.600
  16. Fokkens WJ, Lund VJ, Hopkins C, Hellings PW, Kern R, Reitsma S, Toppila-Salmi S, Bernal-Sprekelsen M, Mullol J. Executive summary of EPOS 2020 including integrated care pathways. Rhinology. 2020;58(2):82-111.  https://doi.org/10.4193/Rhin20.601
  17. Benjamin MR, Stevens WW, Li N, Bose S, Grammer LC, Kern RC, Tan BK, Conley DB, Smith SS, Welch KC, Schleimer RP, Peters AT. Clinical Characteristics of Patients with Chronic Rhinosinusitis without Nasal Polyps in an Academic Setting. The Journal of Allergy and Clinical Immunology. In Practice. 2019:7(3):1010-1016. https://doi.org/10.1016/j.jaip.2018.10.014
  18. Rasouli AA, Dyamely Z.Prevalence of nasal polyps in chronic rhinosinusitis patients undergoing functional endoscopic sinus surgery. Interdisciplinary Approaches to Medicine. 2021;2(1):67-71. 
  19. Stevens WW, Lee RJ, Schleimer RP, Cohen NA. Chronic rhinosinusitis pathogenesis. The Journal of Allergy and Clinical Immunology. 2015;136(6):1442-1453. https://doi.org/10.1016/j.jaci.2015.10.009
  20. Mashinets OO, Davydov RS, Kartashova KI, Saliy OV. Gender and age characteristics of polypous rhinosinusitis in a modern metropolis. Rossijskaya rinologiya. 2011;19(2):24. (In Russ.).
  21. Stevens WW, Peters AT, Tan BK, Klingler AI, Poposki JA, Hulse KE, Grammer LC, Welch KC, Smith SS, Conley DB, Kern RC, Schleimer RP, Kato A. Associations Between Inflammatory Endotypes and Clinical Presentations in Chronic Rhinosinusitis. The Journal of Allergy and Clinical Immunology. In Practice. 2019;7(8):2812-2820.e3.  https://doi.org/10.1016/j.jaip.2019.05.009
  22. Johansson L, Akerlund A, Holmberg K, Melén I, Bende M. Prevalence of nasal polyps in adults: the Skövde population-based study. The Annals of Otology, Rhinology, and Laryngology. 2003;112(7):625-9.  https://doi.org/10.1177/000348940311200709
  23. Larsen K, Tos M. The estimated incidence of symptomatic nasal polyps. Acta Otolaryngologica. 2002;122(2):179-82.  https://doi.org/10.1080/00016480252814199
  24. Starry A, Hardtstock F, Wilke T, Weihing J, Ultsch B, Wernitz M, Renninger M, Maywald U, Pfaar O. Epidemiology and treatment of patients with Chronic rhinosinusitis with nasal polyps in Germany-A claims data study. Allergy. 2022;77(9):2725-2736. https://doi.org/10.1111/all.15301
  25. Vereshchagin MYu, Minkin AU. Polypous rhinosinusitis.E’kologiya cheloveka. 2012;8:54-58. (In Russ.).
  26. Klossek JM, Neukirch F, Pribil C, Jankowski R, Serrano E, Chanal I, El Hasnaoui A. Prevalence of nasal polyposis in France: a cross-sectional, case-control study. Allergy. 2005;60(2):233-7.  https://doi.org/10.1111/j.1398-9995.2005.00688.x
  27. Rudmik L, Smith TL, Schlosser RJ, Hwang PH, Mace JC, Soler ZM. Productivity costs in patients with refractory chronic rhinosinusitis. Laryngoscope. 2014;124(9):2007-12.  https://doi.org/10.1002/lary.24630
  28. Lourijsen ES, Fokkens WJ, Reitsma S. Direct and indirect costs of adult patients with chronic rhinosinusitis with nasal polyps. Rhinology. 2020;58(3):213-217.  https://doi.org/10.4193/Rhin19.468
  29. Ryazantsev SV, Budkovaya MA, Artemyeva ES, Khamgushkeeva NN. Rhinosinusitis with nasal polyps: main aspects of anti-relapse therapy and recovery of nasal breathing. Meditsinskiy sovet. 2019;(20):13-18. (In Russ.). https://doi.org/10.21518/2079-701X-2019-20-13-18
  30. Kato A, Peters AT, Stevens WW, Schleimer RP, Tan BK, Kern RC. Endotypes of chronic rhinosinusitis: Relationships to disease phenotypes, pathogenesis, clinical findings, and treatment approaches. Allergy. 2022;77(3):812-826.  https://doi.org/10.1111/all.15074
  31. Kato A, Schleimer RP, Bleier BS. Mechanisms and pathogenesis of chronic rhinosinusitis. The Journal of Allergy and Clinical Immunology. 2022;149(5):1491-1503. https://doi.org/10.1016/j.jaci.2022.02.016
  32. Piskunov GZ. Clinical phenotypes of polyposis rhinosinusitis. Rossijskaya rinologiya. 2019;27(4):224-231. (In Russ.). https://doi.org/10.17116/rosrino201927041224
  33. Piskunov GZ, Moiseeva YuP. Polipozny’j rinosinusit. M.: MEDpress-inform; 2021. (In Russ.).
  34. Madaminova NE, Narbaev ZK, Ulmasov AO, Ulmasov BB. Assessment of quality of life in patients with chronic rhinosinusitis. Novy’j den’ v medicine. 2020;4(32):438-440. (In Russ.).
  35. Pelishenko TG, Koryagin FN. Modern approaches to the conservative treatment of chronic rhinosinusitis with polyps. Medicinskij alfavit. 2023;5:63-66. (In Russ.).
  36. Pelishenko TG, Kruglova LS, Nagornev SN, Frolkov V.K. Comparative evaluation of the clinical effectiveness of using various methods of medical rehabilitation of patients with polypous rhinosinusitis. Fizioterapevt. 2023;4:15-24. (In Russ.). https://doi.org/10.33920/med-14-2304-02
  37. Nagornev SN, Pelishenko TG, Korchazhkina NB, Frolkov VK. Mechanisms of increasing therapeutic potential in the context of complex application of therapeutic physical factors in patients with chronic polypous rhinosinusitis. Regenerative Biotechnologies, Preventive, Digital and Predictive Medicine. 2024;1(3):24-32. (In Russ.). https://doi.org/10.17116/rbpdpm2024103124
  38. Pelishenko TG. Vliyanie kompleksnoj medicinskoj reabilitacii pacientov s polipozny’m rinosinusitom na dinamiku parametrov mikrocirkulyacii slizistoj obolochki polosti nosa. Aktual’ny’e problemy’ nauchny’x issledovanij: teoreticheskij i prakticheskij aspekty’. Sbornik statej po itogam Mezhdunarodnoj nauchno-prakticheskoj konferencii. Sterlitamak: AMI, 2024: 28-32. (In Russ.).
  39. Pelishenko TG. Dinamika processa POL i antioksidantnoj zashhity’ u pacientov s polipozny’m rinosinusitom pri provedenii kompleksnoj medicinskoj reabilitacii. Sovremenny’e nauchny’e issledovaniya: aktual’ny’e voprosy’, dostizheniya i innovacii. Sbornik statej XXXVII Mezhdunarodnoj nauchno-prakticheskoj konferencii. Penza: MCzNS «Nauka i Prosveshhenie»; 2024: 108-111. (In Russ.).
  40. Pelishenko TG, Koryagin FN, Boyarintsev VV. Conservative treatment of patients with chronic rhinosinusitis with polyps complicated by destruction of the walls of the paranasal sinuses. Kremlevskaya medicina. Klinicheskij vestnik. 2022;4:73-76. (In Russ.).
  41. Pelishenko TG, Kruglova LS, Nagornev SN. Assessing efficacy of comprehensive medical rehabilitation of patients with polypoid rhinosinusitis on the basis of correlation adaptometry method. Fizioterapevt. 2024;1:60-70. (In Russ.). https://doi.org/10.33920/med-14-2401-07
  42. Abramovich SG, Larionova EM. Osnovy’ klinicheskoj fizioterapii v otorinolaringologii. Irkutsk: RIO GBOU DPO IGMAPO; 2011.
  43. Samsonov VP, Zakharova EV, Zavarzina EV, Katola VM. Complex conservative treatment of polypous rhinosinusitis in patients with bronchial asthma. Byulleten’ fiziologii i patologii dy’xaniya. 2008;28:54-56. (In Russ.).
  44. Ponomarenko GN, Ulashhik VS. Fizioterapiya: uchebnik. M.: GEOTAR-Media; 2015. (In Russ.).
  45. Fizicheskaya i reabilitacionnaya medicina. Nacional’noe rukovodstvo. Pod red. GN Ponomarenko. M.: GE’OTAR-Media; 2023. (In Russ.).
  46. Mezhdunarodnaya klassifikaciya funkcionirovaniya, ogranichenij zhiznedeyatel’nosti i zdorov’ya: 54-ya sessiya assamblei Vsemirnoj organizacii zdravooxraneniya 22 maya 2001 goda. Bibliotechnaya sluzhba VOZ. SPb: Sankt-Peterburgskij institut usovershenstvovaniya vrachej-e’kspertov Ministerstva truda i social’nogo razvitiya Rossijskoj Federacii; 2003. (In Russ.).
  47. Shoshmin AV, Ponomarenko GN. MKF v reabilitacii. Izdanie 2-e, pererab. i dop. SPb, 2020. (In Russ.).
  48. Nagornev SN, Pelishenko TG, Kruglova LS. Evaluation of the effectiveness of complex medical rehabilitation of patients with polypous rhinosinusitis based on the international classification of functioning, disability and health. Fizioterapevt. 2024;2(164):57-67. (In Russ.). https://doi.org/10.33920/med-14-2402-07
  49. Pelishenko TG, Kruglova LN, Nagornev SN. Evaluation of the effectiveness of complex medical rehabilitation of patients with polypous rhinosinusitis associated with atopic dermatitis using ICF. Fizioterapiya, bal’neologiya i reabilitaciya. 2023;22(5):345-356. (In Russ.). https://doi.org/10.17816/rjpbr627528
  50. Pelishenko TG, Nagornev SN, Kruglova LS. Application of the International Classification of Functioning, Disability and Health to assess the effectiveness of rehabilitation of patients with polypous rhinosinusitis associated with bronchial asthma. Russian Journal of Environmental and Rehabilitation Medicine. 2024;2:35-45. (In Russ.).
  51. Ulashchik VS. Combined physiotherapy: general information, interaction of physical factors. Voprosy’ kurortologii, fizioterapii i lechebnoj fizicheskoj kul’tury’. 2016;6:4-11. (In Russ.).
  52. Pelishenko TG, Nagornev SN, Korchazhkina NB, Kruglova LS. Therapeutic physical factors in correction of systemic mechanisms of comorbidity in patients with polypous rhinosinusitis. Regenerative Biotechnologies, Preventive, Digital and Predictive Medicine. 2024;1(1):5-12. (In Russ.). https://doi.org/10.17116/rbpdpm202410115
  53. Pelishenko TG, Kruglova LS, Nagornev SN. Features of complex medical rehabilitation of patients with polypous rhinosinusitis associated with atopic dermatitis. Russian Journal of Environmental and Rehabilitation Medicine. Rossijskij zhurnal e’kologicheskoj i vosstanovitel’noj mediciny’. 2023;3:14-25. (In Russ.).
  54. Pelishenko TG, Kruglova LS, Nagornev SN, Boyarintsev VV. A personalized approach to the application of medical rehabilitation methods for patients with polypous rhinosinusitis associated with atopic dermatitis. Russian Journal of Environmental and Rehabilitation Medicine. 2024;3:51-57. (In Russ.).
  55. Pelishenko TG, Kruglova LS. The effect of combined physiotherapy on humoral immunity, cytokine profile and inflammatory reactions in patients with polypous rhinosinusitis. Fizioterapevt. 2023;6:42-49. (In Russ.). https://doi.org/10.33920/med-14-2306-04
  56. Bachert C, Hellings PW, Mullol J, Hamilos DL, Gevaert P, Naclerio RM, Joish VN, Chao J, Mannent LP, Amin N, Abbe A, Taniou C, Fan C, Pirozzi G, Graham NMH, Mahajan P, Staudinger H, Khan A. Dupilumab improves health-related quality of life in patients with chronic rhinosinusitis with nasal polyposis. Allergy. 2020;75(1):148-157.  https://doi.org/10.1111/all.13984
  57. Bachert C, Han JK, Desrosiers M, Hellings PW, Amin N, Lee SE, Mullol J, Greos LS, Bosso JV, Laidlaw TM, Cervin AU, Maspero JF, Hopkins C, Olze H, Canonica GW, Paggiaro P, Cho SH, Fokkens WJ, Fujieda S, Zhang M, Lu X, Fan C, Draikiwicz S, Kamat SA, Khan A, Pirozzi G, Patel N, Graham NMH, Ruddy M, Staudinger H, Weinreich D, Stahl N, Yancopoulos GD, Mannent LP. Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials. Lancet. 2019;394(10209):1638-1650. https://doi.org/10.1016/S0140-6736(19)31881-1
  58. Bachert C, Marple B, Hosemann W, Cavaliere C, Wen W, Zhang N. Endotypes of Chronic Rhinosinusitis with Nasal Polyps: Pathology and Possible Therapeutic Implications. The Journal of Allergy and Clinical Immunology. In Practice. 2020;8(5):1514-1519. https://doi.org/10.1016/j.jaip.2020.03.007
  59. Bachert C, Luong AU, Gevaert P, Mullol J, Smith SG, Silver J, Sousa AR, Howarth PH, Benson VS, Mayer B, Chan RH, Busse WW. The Unified Airway Hypothesis: Evidence from Specific Intervention With Anti-IL-5 Biologic Therapy. The Journal of Allergy and Clinical Immunology. In Practice. 2023;11(9):2630-2641. https://doi.org/10.1016/j.jaip.2023.05.011
Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.