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Belova A.N.

Privolzhsky Research Medical University

Israelyan Yu.A.

Privolzhsky Research Medical University

Sushin V.O.

Privolzhsky Research Medical University

Shabanova M.A.

Privolzhsky Research Medical University

Rezenova A.M.

Privolzhsky Research Medical University

Transcranial photobiomodulation in therapy of neurodegenerative diseases of the brain: theoretical background and clinical effectiveness

Authors:

Belova A.N., Israelyan Yu.A., Sushin V.O., Shabanova M.A., Rezenova A.M.

More about the authors

Journal: Problems of Balneology, Physiotherapy and Exercise Therapy. 2021;98(6): 61‑67

DOI: 10.17116/kurort20219806161

Read: 5528 times

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Table of contents

TRANSCRANIAL PHOTOBIOMODULATION IN THERAPY OF NEURODEGENERATIVE DISEASES OF THE BRAIN: THEORETICAL BACKGROUND AND CLINICAL EFFECTIVENESS
TRANSCRANIAL PHOTOBIOMODULATION IN THERAPY OF NEURODEGENERATIVE DISEASES OF THE BRAIN: THEORETICAL BACKGROUND AND CLINICAL EFFECTIVENESS

To cite this article:

Belova AN, Israelyan YuA, Sushin VO, Shabanova MA, Rezenova AM. Transcranial photobiomodulation in therapy of neurodegenerative diseases of the brain: theoretical background and clinical effectiveness. Problems of Balneology, Physiotherapy and Exercise Therapy. 2021;98(6):61‑67. (In Russ.)
https://doi.org/10.17116/kurort20219806161

Подписка 2026 Вопросы курортологии, физиотерапии и лечебной физической культуры (Problems of Balneology, Physiotherapy and Exercise Therapy)
 
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Abstract:

Transcranial photobiomodulation (tPBM) is a form of light therapy that uses monochromatic visible and infrared light from non-ionizing radiation sources (lasers, LEDs) placed on the scalp, forehead, or intranasally to project light directly to target areas of the brain. Accumulated experimental and clinical data indicate the safety and potential efficacy of tPBM in some central nervous system diseases.This article briefly reviews the general concepts of tPBM, the results of experimental and clinical studies on the efficacy of tPBM in Alzheimer’s disease, Parkinson’s disease, and brain stroke. The possible mechanisms of the tPBM therapeutic effect and the need to choose optimal exposure parameters are discussed. Although the evidence base regarding the efficacy of tPBM in neurodegenerative and vascular brain diseases is still insufficient, analysis of the published data justifies considering tPBM as a promising method of adjuvant therapy for some central nervous system diseases.

Keywords:

transcranial photobiomodulation
low-intensity laser therapy
brain
central nervous system
diseases

Authors:

Belova A.N.

Privolzhsky Research Medical University

Israelyan Yu.A.

Privolzhsky Research Medical University

Sushin V.O.

Privolzhsky Research Medical University

Shabanova M.A.

Privolzhsky Research Medical University

Rezenova A.M.

Privolzhsky Research Medical University

Received:

05.02.2021

Accepted:

26.04.2021

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