The effectiveness of endonasal electrophoresis of neuroprotective agents used in the rehabilitative treatment of the patients presenting with primary open angle glaucoma

Nazarova G.A.; Konchugova T.V.; Iurova O.V.; Sichinava N.V.; Turova E.A.; Rassulova M.A.; Morozova N.E.

doi:https://doi.org/

Nazarova G.A.

FGBU "Rossiĭskiĭ nauchnyĭ tsentr meditsinskoĭ reabilitatsii i kurortologii" Minzdrava RF, Moskva

Konchugova T.V.

FGBU Rossiĭskiĭ nauchnyĭ tsentr kurortologii Minzdrava Rossii, Moskva

Iurova O.V.

GBUZ "MNPTs meditsinskoĭ reabilitatsii, vosstanovitel'noĭ i sportivnoĭ meditsiny" Departamenta zdravookhraneniia Moskvy

Sichinava N.V.

FGBU "Rossiĭskiĭ nauchnyĭ tsentr meditsinskoĭ reabilitatsii i kurortologii" Minzdravsotsrazvitiia Rossii, Moskva

Turova E.A.

Siberian Regional Hospital №1, Yekaterinburg, Russia

Rassulova M.A.

GBUZ "MNPTs meditsinskoĭ reabilitatsii, vosstanovitel'noĭ i sportivnoĭ meditsiny" Departamenta zdravookhraneniia Moskvy

Morozova N.E.

FGBU "Rossiĭskiĭ nauchnyĭ tsentr meditsinskoĭ reabilitatsii i kurortologii" Minzdrava Rossii

The effectiveness of endonasal electrophoresis of neuroprotective agents used in the rehabilitative treatment of the patients presenting with primary open angle glaucoma

Authors:

Nazarova G.A., Konchugova T.V., Iurova O.V., Sichinava N.V., Turova E.A., Rassulova M.A., Morozova N.E.

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Journal: Problems of Balneology, Physiotherapy and Exercise Therapy. 2013;90(6): 27‑30

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To cite this article:

Nazarova GA, Konchugova TV, Iurova OV, Sichinava NV, Turova EA, Rassulova MA, Morozova NE. The effectiveness of endonasal electrophoresis of neuroprotective agents used in the rehabilitative treatment of the patients presenting with primary open angle glaucoma. Problems of Balneology, Physiotherapy and Exercise Therapy. 2013;90(6):27‑30. (In Russ.)

Подписка 2026 Вопросы курортологии, физиотерапии и лечебной физической культуры (Problems of Balneology, Physiotherapy and Exercise Therapy)

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Abstract:

The objective of the present study was to estimate the effectiveness of the peptide drug cortexin used to treat primary open angle glaucoma. It was shown that endonasal electrophoresis of cortexin resulted in more pronounced positive changes in the dynamics of clinical, functional, perimetric, and electrophysiological characteristics compared with intramuscular administration of the same drug to the patients of the control group. This difference was apparent both immediately after the termination of the treatment and during the long-term follow-up.

Keywords:

primary open angle glaucoma

conservative treatment and physiotherapeutic procedures

peptides

neuroprotective agents

endonasal electrophoresis

Authors:

Nazarova G.A.

FGBU "Rossiĭskiĭ nauchnyĭ tsentr meditsinskoĭ reabilitatsii i kurortologii" Minzdrava RF, Moskva

Konchugova T.V.

FGBU Rossiĭskiĭ nauchnyĭ tsentr kurortologii Minzdrava Rossii, Moskva

Iurova O.V.

GBUZ "MNPTs meditsinskoĭ reabilitatsii, vosstanovitel'noĭ i sportivnoĭ meditsiny" Departamenta zdravookhraneniia Moskvy

Sichinava N.V.

FGBU "Rossiĭskiĭ nauchnyĭ tsentr meditsinskoĭ reabilitatsii i kurortologii" Minzdravsotsrazvitiia Rossii, Moskva

Turova E.A.

Siberian Regional Hospital №1, Yekaterinburg, Russia

Rassulova M.A.

GBUZ "MNPTs meditsinskoĭ reabilitatsii, vosstanovitel'noĭ i sportivnoĭ meditsiny" Departamenta zdravookhraneniia Moskvy

Morozova N.E.

FGBU "Rossiĭskiĭ nauchnyĭ tsentr meditsinskoĭ reabilitatsii i kurortologii" Minzdrava Rossii

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References:

Arutyunova O.V. Kontseptsiya razvitiya oftal'mologicheskogo napravleniya v ramkakh vosstanovitel'noy meditsiny [The concept of the development of the ophthalmological studies in the framework of rehabilitative medicine]. Vestnik vosstanovitel'noy meditsiny. 2006; 2: 7-10. [In Russian].
Razumov A.N., Ovechkin I.G., Bobrovnitskiy I.P., Shakula A.V., Arutyunova O.V., Kozhukhov A.A. Vosstanovitel'naya oftal'mologiya. Razumov A.N., Ovechkin I.G., red. M.: Voentekhizdat; 2006. 96 s. [Rehabilitative ophthalmology. Razumov A.N., Ovechkin I.G., eds. M.: Voentekhizdat; 2006. 96 p]. [In Russian].
Bobrovnitskiy I.P., Lebedeva O.D., Yakovlev M.Yu. Otsenka funktsional'nykh rezervov organizma i vyyavlenie lits grupp riska rasprostranennykh zabolevaniy riska rasprostranennykh zabolevaniy [The assessment of the functional reserves of the body and the identification of the groups at risk of developing common diseases] . Voprosy kurortologii, fizioterapii i lechebnoy fizicheskoy kul'tury. 2011; 6: 40-43. [In Russian].
Varma R., Lee P.P., Goldberg I., Kotak S. An assessment of the health and economic burdens of glaucoma. Am. J. Ophthalmol. 2011; 152 (4): 515-22.
Stefan C., Cojocaru I., Pop A. Alternative treatments in glaucoma, independent from ocular pressure. Oftalmologia. 2011; 55 (2): 7-11.
Wilson A.M., Di Polo A. Gene therapy for retinal ganglion cell neuroprotection in glaucoma. Gene Ther. 2012; 19 (2): 127-36.
Avetisov S.E., Polunin G.S., Markov I.A. Fizioterapevticheskie metody. V kn.: Avetisov S.E., Egorov E.A., Moshetova L.K., Neroev V.V., Takhchidi Kh.P., red. Oftal'mologiya. Natsional'noe rukovodstvo. M.: GEOTAR-Media; 2008: 177-187. [Physiotherapeutic methods. In: Ophthalmology. The national guidelines. Avetisov S.E., Egorov E.A., Moshetova L.K., Neroev V.V., Takhchidi Kh.P., eds. M.: GEOTAR-Media; 2008: 177-187]. [In Russian].
Kamenskikh T.G., Arutyunova O.V., Raygorodskiy Yu.M., Myshkina E.Yu. Tsvetoritmoterapiya v korrektsii psikhosomaticheskikh zritel'nykh narusheniy u bol'nykh s khronicheskoy oftal'mopatologiey [Colour rhythmotherapy for the correction of psychosomatic visual abnormalities in patients with chronic ophthalmopathia]. Voprosy kurortologii, fizioterapii i lechebnoy fizicheskoy kul'tury. 2008; 6: 29-32. [In Russian].
Kozhukhov A.A. Metody fizioterapii v oftal'mologii [The application of physiotherapeutic methods in ophthalmology]. Voprosy kurortologii, fizioterapii i lechebnoy fizicheskoy kul'tury. 2006; 3: 42-44. [In Russian].
Marchenko L.N. Neyroprotektsiya pri zabolevaniyakh setchatkii zritel'nogo nerva. Minsk: UP IVTs Minfina; 2003. 363 s. [Neuroprotection in the retinal and optic nerve diseases. Minsk: UP IVTs Minfina; 2003. 363 p.]. [In Russian].
Minenkov A.A., Orekhova E.M., Gorbunov F.E., Slepushkina T.G., Kubalova M.I., Krupennikov A.I., Konchugova T.V., Lapochkin O.L., Kuvyrkina I.K., Isaev S.V. Sochetanie fizicheskikh faktorov pri razlichnykh zabolevaniyakh. Posobie dlya vrachey [The combination of physical factors in various isreases. Guidelines for physicians]. Voprosy kurortologii, fizioterapii i lechebnoy fizicheskoy kul'tury. 2006; 1: 47-51. [In Russian].
Nepomnyashchikh V.A., Vovk T.N. Opyt primeneniya peptidnykh bioregulyatorov v kompleksnom lechenii glaukomy i drugikh zabolevaniy organa zreniya [The experience with the application of peptide bioregulators for the combined treatment of glaucoma and other visual disturbances]. Naturoterapiya i gomeopatiya. 2005; 1: 47-50. [In Russian].
Okovitov V.V. Metody fizioterapii v oftal'mologii. M.: TsVNIAG; 1999. 158 s. [[Physiotherapeutic methods in ophthalmology. M.: TsVNIAG; 1999. 158 p.]. [In Russian].
Shakula A.V., Emel'yanov G.A., Shchukin S.Yu. Sovremennye metody fizioterapevticheskogo vozdeystviya na akkomodatsionno-refraktsionnuyu sistemu glaza [The modern methods of physiotherapeutic treatment of the accommodation and refraction system of the eye]. Vestnik vosstanovitel'noy meditsiny. 2012; 4: 68-72. [In Russian].
Shakula A.V., Mel'nikova E.A. Effektivnost' primeneniya meditsinskoy tekhnologii endonazal'nogo elektroforeza s korteksinom pri khronicheskoy ustalosti [The effectiveness of application of the medical technology of endonasal electrophoresis of cortexin for the management of chronic fatigue]. Vestnik vosstanovitel'noy meditsiny. 2007; 1: 39-41. [In Russian].