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Laberko E.L.

Kafedra otorinolaringologii pediatricheskogo fakul'teta RNIMU im. N.I. Pirogova Minzdrava Rossii Moskva, Rossiia, 117997

Talalaev A.G.

Morozovskaya City Children's Clinical Hospital Moscow Health Department, Moscow, Russia, 119049

Bogomil'skiĭ M.R.

Kafedra otolaringologii pediatricheskogo fakul'teta Rossiĭskogo natsional'nogo issledovatel'skogo meditsinskogo universiteta im. N.I. Pirogova

Bullikh A.V.

N.I. Pirogov Russian National Research Medical University, Russian Ministry of Health, Moscow, Russia, 117997

The method for the direct evaluation of the state of mucociliary clearance in the children

Authors:

Laberko E.L., Talalaev A.G., Bogomil'skiĭ M.R., Bullikh A.V.

More about the authors

Journal: Russian Bulletin of Otorhinolaryngology. 2015;80(2): 40‑44

DOI: 10.17116/otorino201580240-44

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Table of contents

THE METHOD FOR THE DIRECT EVALUATION OF THE STATE OF MUCOCILIARY CLEARANCE IN THE CHILDREN
THE METHOD FOR THE DIRECT EVALUATION OF THE STATE OF MUCOCILIARY CLEARANCE IN THE CHILDREN

To cite this article:

Laberko EL, Talalaev AG, Bogomil'skiĭ MR, Bullikh AV. The method for the direct evaluation of the state of mucociliary clearance in the children. Russian Bulletin of Otorhinolaryngology. 2015;80(2):40‑44. (In Russ.)
https://doi.org/10.17116/otorino201580240-44

Подписка 2026 Вестник оториноларингологии (Russian Bulletin of Otorhinolaryngology)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

The objective of the present study was to develop a readily available, simple to use and acceptable for the application in the childhood method for the evaluation of the state of mucociliary clearance. We have proposed and presented the detailed description of the simple approach to the direct investigation of the ciliary apparatus of the ciliary epithelium cells that requires neither the expensive sophisticated equipment nor the software programs to be implemented. Investigations by this method made it possible to elucidate and identify certain details of the functioning of ciliary epithelium. Oher methods for the study of the ciliary apparatus are considered with special reference to their main advantages and disadvantages. Some debatable problems pertaining to the choice of optimal techniques for the evaluation of the functional state of ciliary epithelium are discussed.

Keywords:

cilium
ciliary apparatus
mucociliary clearance
ciliary beat frequency
nasal mucosa

Authors:

Laberko E.L.

Kafedra otorinolaringologii pediatricheskogo fakul'teta RNIMU im. N.I. Pirogova Minzdrava Rossii Moskva, Rossiia, 117997

Talalaev A.G.

Morozovskaya City Children's Clinical Hospital Moscow Health Department, Moscow, Russia, 119049

Bogomil'skiĭ M.R.

Kafedra otolaringologii pediatricheskogo fakul'teta Rossiĭskogo natsional'nogo issledovatel'skogo meditsinskogo universiteta im. N.I. Pirogova

Bullikh A.V.

N.I. Pirogov Russian National Research Medical University, Russian Ministry of Health, Moscow, Russia, 117997

Close metadata

References:

  1. Piskunov G.Z., Piskunov S.Z. Klinicheskaya rinologiya. M: MIA 2006.
  2. Piskunov S.Z., Piskunov G.Z., Kharchenko V.V., Dolzhikov A.A. Funktsional'naya anatomiya i khirurgiya nosa i okolonosovykh pazukh. Kursk 2004.
  3. Rikhel'man G., Lopatin A.S. Mukotsiliarnyi transport: eksperimental'naya i klinicheskaya otsenka. Ros rinol 1994; 4: 33—47.
  4. Seybold Z.V., Mariassy A.T., Stroh D., Kim C.S., Gazeroglu H., Wanner A. Mucociliary interaction in vitro: effects of physiological and inflammatory stimuli. J Appl Physiol 1990; 68: 4: 1421—1426.
  5. Cohen N.A. Sinonasal mucociliary clearance in health and disease. Ann Otol Rhinol Laryngol Suppl 2006; 196: 20—26.
  6. Sleigh M.A. The co-ordination and control of cilia. Symp Soc Exp Biol 1996; 20: 11—31.
  7. Messerklinger W. Direction of ciliary flow on the mucosa of the upper respiratory tract. Z Laryngol Rhinol Otol 1951; 30: 7—8: 302—308.
  8. Proetz A. Essays on the applied physiology of the nose. St. Loius: Annals Publishing Co 1953.
  9. Dalhamn T., Skog E. The reaction of the tracheal mucosa to pollen, with special reference to ciliary beat frequency. Acta Otolaryngol 1958; 49: 2: 93—97.
  10. Dalhamm T., Holma B., Tomenius L. In vitro studies of the ciliotoxic action of ethanol vapour in relation to its concentration in tracheal tissue. Acta Pharmacol Toxicol (Copenh) 1967; 25: 2: 272—280.
  11. Ingels K.J., Kortmann M.J., Nijziel M.R., Graamans K., Huizing E.H. Factors influencing ciliary beat measurements. Rhinology 1991; 29: 1: 17—26.
  12. Kozlov V.S., Shilenkova V.V., Azatyan A.S., Kramnoi A.I. Mukotsiliarnyi transport i dvigatel'naya aktivnost' tsiliarnogo apparata slizistoi obolochki nosa u bol'nykh khronicheskim polipoznym rinosinusitom. Vestn otorinolar 2008; 2: 10—13.
  13. Shilenkova V.V. Chastota bieniya resnichek mertsatel'nogo epiteliya polosti nosa u zdorovykh detei. Ros otorinolar 2008; 2: 87—89.
  14. Ruzhitskaya E.A., Smirnova M.O., Zakharov P.P. Diagnosticheskoe znachenie issledovaniya mertsatel'nogo epiteliya slizistoi obolochki respiratornogo epiteliya. Klin lab diagn 2005; 5: 38—39.
  15. Thomas B., Rutman A., O’Callaghan C. Disrupted ciliated epithelium shows slower ciliary beat frequency and increased dyskinesia. Eur Respir J 2009; 34: 2: 401—404.
  16. Min Y.G., Yun Y.S., Rhee C.S., Sung M.W., Lee K.S., Ju M.S., Park K.S. Effects of phenylephrine on ciliary beat in human nasal respiratory epithelium: quantitative measurement by video-computerized analysis. Laryngoscope 1998; 108: 3: 418—421.
  17. Hofmann T., Wolf G., Koidl B. In vitro studies of the effect of vasoconstrictor nose drops on ciliary epithelium of human nasal mucosa. Laryngorhinootologie 1995; 74: 9: 564—567.
  18. Shaari J., Palmer J.N., Chiu A.G. Regional analysis of sinonasal ciliary beat frequency. Am J Rhinol 2006; 20: 2: 150—154.
  19. Riechelmann H., Brommer C., Hinni M., Martin C. Response of human ciliated respiratory cells to a mixture of menthol, eucalyptus oil and pine needle oil. Arzneimittelforschung 1997; 47: 9: 1035—1039.
  20. Cohen N.A., Zhang S., Sharp D.B. Cigarette smoke condensate inhibits transepithelial chloride transport and ciliary beat frequency. Laryngoscope 2009; 119: 11: 2269—2274.
  21. Chilvers M.A., Rutman A., O’Callaghan C. Functional analysis of cilia and ciliated epithelial ultrastructure in healthy children and young adults. Thorax 2003; 58: 4: 333—338.
  22. Borum P., Holten A., Loekkegaard N. Depression of nasal mucociliary transport by an aerosol hair-spray. Scand J Respir Dis 1979; 60: 5: 253—259.
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