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Krukov A.I.

Sverzhevsky Moscow Scientific and Practical Othorhinolaryngology Center, Moscow

Tsarapkin G.Yu.

Sverzhevskiy Otorhinolaryngology Healthcare Research Institute, Moscow Department of Healthcare, Moscow, Russia

Margolin O.V.

Gematologicheskiĭ nauchnyĭ tsentr Minzdrava Rossii, Moskva

Gorovaia E.V.

Moskovskiĭ nauchno-prakticheskiĭ tsentr otorinolaringologii Departamenta zdravookhraneniia Moskvy

Fedotkina K.M.

GBUZ "Moskovskiĭ nauchno-prakticheskiĭ tsentr otorinolaringologii" Departamenta zdravookhraneniia Moskvy

Vasil'ev S.A.

Rossiĭskiĭ nauchnyĭ tsentr khirurgii im. akad. B.V. Petrovskogo RAMN, Moskva

The phenomenon of vascular microthrombosis in mucoperichondrium associated with plastic closure of nasal septum perforations

Authors:

Krukov A.I., Tsarapkin G.Yu., Margolin O.V., Gorovaia E.V., Fedotkina K.M., Vasil'ev S.A.

More about the authors

Journal: Russian Bulletin of Otorhinolaryngology. 2013;78(5): 14‑17

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THE PHENOMENON OF VASCULAR MICROTHROMBOSIS IN MUCOPERICHONDRIUM ASSOCIATED WITH PLASTIC CLOSURE OF NASAL SEPTUM PERFORATIONS
THE PHENOMENON OF VASCULAR MICROTHROMBOSIS IN MUCOPERICHONDRIUM ASSOCIATED WITH PLASTIC CLOSURE OF NASAL SEPTUM PERFORATIONS

To cite this article:

Krukov AI, Tsarapkin GYu, Margolin OV, Gorovaia EV, Fedotkina KM, Vasil'ev SA. The phenomenon of vascular microthrombosis in mucoperichondrium associated with plastic closure of nasal septum perforations. Russian Bulletin of Otorhinolaryngology. 2013;78(5):14‑17. (In Russ.)

Подписка 2025-2 (Russian Bulletin of Otorhinolaryngology)
 
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The objective of the present study was to identify specific hematological features characterizing the pathophysological processes of clinical significance associated with plastic closure of nasal septum perforations. Changes of clinical, biochemical, and coagulation-related blood characteristics developing as a result of the surgical treatment of the patients with ENT pathology were analysed. It was shown that D-dimer is a specific hematological characteristic that reflects the phenomenon of postoperative vascular microthrombosis in mucoperichondrial-periosteal flaps associated with plastic closure of nasal septum perforations. Based on the results of this study, the authors recommend to prescribe low-molecular weight heparins for prophylactic purposes to the patients undergoing plastic closure of nasal septum perforations.

Keywords:

D-dimer
perforation of nasal septum
heparin
thrombosis
septoplasty

Authors:

Krukov A.I.

Sverzhevsky Moscow Scientific and Practical Othorhinolaryngology Center, Moscow

Tsarapkin G.Yu.

Sverzhevskiy Otorhinolaryngology Healthcare Research Institute, Moscow Department of Healthcare, Moscow, Russia

Margolin O.V.

Gematologicheskiĭ nauchnyĭ tsentr Minzdrava Rossii, Moskva

Gorovaia E.V.

Moskovskiĭ nauchno-prakticheskiĭ tsentr otorinolaringologii Departamenta zdravookhraneniia Moskvy

Fedotkina K.M.

GBUZ "Moskovskiĭ nauchno-prakticheskiĭ tsentr otorinolaringologii" Departamenta zdravookhraneniia Moskvy

Vasil'ev S.A.

Rossiĭskiĭ nauchnyĭ tsentr khirurgii im. akad. B.V. Petrovskogo RAMN, Moskva

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  8. Kryukov A.I., Tsarapkin G.Yu., Turovskii A.B. Original'nyi sposob opredeleniya formy i fiksatsii septal'nykh stentov. Vestn otorinolar 2008; 3: 42-45.
  9. Amin A.N., Lin J., Lenhart G., Schulman K.L. Clinical and economic outcomes in patients at risk of venous thromboembolism receiving appropriate enoxaparin or unfractionated heparin prophylaxis. Thromb Haemost 2009; 102: 2: 321-326.
  10. Savel'ev V.S., Kirienko A.I., Zolotukhin I.A., Andriyashkin V.V. Profilaktika posleoperatsionnykh venoznykh tromboembolicheskikh oslozhnenii v rossiiskikh statsionarakh (predvaritel'nye rezul'taty proekta "Territoriya bezopasnosti"). Flebologiya 2010; 3: 7-12.
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