Doppler ultrasound in the assessment of blood supply to choroidal melanoma: parallels with contrast angiography and histography

Panova I.E.; Samkovich E.V.; Nechiporenko P.A.

doi:https://doi.org/10.17116/oftalma202313901127

Panova I.E.

St. Petersburg branch of S.N. Fyodorov National Medical Research Center «MNTK «Eye Microsurgery»

ORCID: 0000-0001-7443-4555

Samkovich E.V.

Saint Petersburg branch of S.N. Fyodorov National Medical Research Center «MNTK «Eye Microsurgery»

Nechiporenko P.A.

Pavlov First Saint Petersburg State Medical University (Pavlov University)

Doppler ultrasound in the assessment of blood supply to choroidal melanoma: parallels with contrast angiography and histography

Authors:

Panova I.E., Samkovich E.V., Nechiporenko P.A.

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Journal: Russian Annals of Ophthalmology. 2023;139(1): 27‑34

DOI: 10.17116/oftalma202313901127

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To cite this article:

Panova IE, Samkovich EV, Nechiporenko PA. Doppler ultrasound in the assessment of blood supply to choroidal melanoma: parallels with contrast angiography and histography. Russian Annals of Ophthalmology. 2023;139(1):27‑34. (In Russ.)
https://doi.org/10.17116/oftalma202313901127

Подписка 2026 Вестник офтальмологии (Russian Annals of Ophthalmology)

Использование инфографики авторами научных работ

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PURPOSE

Evaluation of blood supply to choroidal melanoma based on comparison of Doppler characteristics of blood flow with angiographic variant of angioarchitectonics and densitometric parameters of the tumor.

MATERIAL AND METHODS

The study was performed in 135 patients (135 eyes) with choroidal melanoma. The initial prominence of the tumors varied from 0.6 to 15.2 mm (mean 5.07±3.58 mm), the diameter of the tumor base varied from 4.1 to 22 mm (mean 10.97±3.62 mm). Taking into account the biometric characteristics of choroidal melanoma, all patients were divided into 3 groups: «small» (n=49), «medium» (n=34) and «large» (n=52). In addition to standard diagnostic examination, the following instrumental methods for assessing the blood supply of choroidal melanoma were carried out: angiography with indocyanine green, optical coherence tomography angiography, ultrasound in color Doppler mapping mode, ultrasound histography.

RESULTS

Comparative analysis of Doppler ultrasound and contrast angiography data in assessing the blood supply of choroidal melanoma established that the first angiographic type, presented by straight and parallel vessels (65%, p=0.037), is characteristic for hypovascular and avascular masses, the second type — for hypervascular choroidal melanomas, in which the new vessels can take the form of arches, loops and nets (68%, p=0.027). The study of densitometric characteristics in choroidal melanoma of various sizes indicates a natural decrease in the acoustic density of the tumor tissue with increase in the prominence of the mass, while there are significant differences in the acoustic density values in hypo/avascular (36.53±5.37 dB) and hypervascular variants (29.28±4.53 dB) of blood supply to tumor tissue.

CONCLUSION

The obtained data on acoustic density of choroidal melanoma can be used in clinical practice for indirect assessment of the nature of blood supply to choroidal melanoma.

Keywords:

choroidal melanoma

blood supply to choroidal melanoma

color Doppler ultrasound

ultrasound histography

indocyanine green angiography

angioarchitectonics of choroidal melanoma

ophthalmic oncology

Authors:

Panova I.E.

St. Petersburg branch of S.N. Fyodorov National Medical Research Center «MNTK «Eye Microsurgery»

ORCID: 0000-0001-7443-4555

Samkovich E.V.

Saint Petersburg branch of S.N. Fyodorov National Medical Research Center «MNTK «Eye Microsurgery»

Nechiporenko P.A.

Pavlov First Saint Petersburg State Medical University (Pavlov University)

Received:

19.09.2021

Accepted:

18.10.2021

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