Anti-VEGF therapy in the treatment of neovascularization secondary to angioid streaks (a case report)

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The article presents a clinical case of using anti-VEGF therapy in the treatment of retinal neovascularization consequent to angioid streaks (AS). Angioid streaks are linear breaks or divergences in an abnormally brittle or calcified Bruch’s membrane. The development of choroidal neovascularization (CNV) due to AS is one of the most serious complications of the disease and the main cause of visual impairment, especially in active middle-aged patients. Currently, determination of the morphology and activity of CNV is done using multimodal macular imaging methods such as optical coherence tomography of the retina (OCT), optical coherence tomography angiography (OCT-A), fluorescin angiography (FA), indocyanine green angiography (ICGA) and autofluorescence. With the discovery of anti-VEGF therapy, it became possible to improve and stabilize functional results in this group of patients.

Keywords:

angioid streaks

choroidal neovascularisation

ranibizumab

anti-VEGF

Authors:

Shelankova A.V.

Research Institute of Eye Diseases

Budzinskaya M.V.

Krasnov Research Institute of Eye Diseases

SPIN RSCI: 3552-7061
Scopus AuthorID: 6508005851
ResearcherID: C-3026-2014
ORCID: 0000-0002-5507-8775

Received:

30.05.2020

Accepted:

08.06.2020

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