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Budzinskaia M.V.
FGBU "Nauchno-issledovatel'skiĭ institut glaznykh bolezneĭ" RAMN, Moskva
Age-related macular degeneration
Journal: Russian Annals of Ophthalmology. 2014;130(6): 56‑61
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To cite this article:
Budzinskaia MV. Age-related macular degeneration. Russian Annals of Ophthalmology. 2014;130(6):56‑61. (In Russ.)
The review provides an update on the pathogenesis and new treatment modalities for neovascular age-related macular degeneration (AMD). The impact of polymorphism in particular genes, including complement factor H (CFH), age-related maculopathy susceptibility 2 (ARMS2/LOC387715), and serine peptidase (HTRA1), on AMD development is discussed. Clinical presentations of different forms of exudative AMD, that is classic, occult, or more often mixed choroidal neovascularization, retinal angiomatous proliferation, and choroidal polypoidal vasculopathy, are described. Particular attention is paid to the results of recent clinical trials and safety issues around the therapy.
Authors:
Budzinskaia M.V.
FGBU "Nauchno-issledovatel'skiĭ institut glaznykh bolezneĭ" RAMN, Moskva
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