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Tikunova E.V.

FGAOU VPO "Belgorodskiĭ gosudarstvennyĭ natsional'nyĭ issledovatel'skiĭ universitet"

Churnosov M.I.

Kafedra mediko-biologicheskikh distsiplin Belgorodskogo gosudarstvennogo natsional'nogo issledovatel'skogo universiteta

Genetic studies of primary open-angle glaucoma

Authors:

Tikunova E.V., Churnosov M.I.

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Journal: Russian Annals of Ophthalmology. 2014;130(5): 96‑99

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Tikunova EV, Churnosov MI. Genetic studies of primary open-angle glaucoma. Russian Annals of Ophthalmology. 2014;130(5):96‑99. (In Russ.)

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The present review is devoted to genetic studies of primary open-angle glaucoma (POAG). Today, POAG is considered a multifactorial disease with threshold effect, which is associated with single or multiple genes mutation as well as external influences. According to molecular genetic studies, three causative genes (MYOC, optinevrin, WDR 36) and several dosens of candidate genes are involved in the development of POAG.

Keywords:

primary open-angle glaucoma
MYOC
optinevrin
WDR 36
candidate genes.

Authors:

Tikunova E.V.

FGAOU VPO "Belgorodskiĭ gosudarstvennyĭ natsional'nyĭ issledovatel'skiĭ universitet"

Churnosov M.I.

Kafedra mediko-biologicheskikh distsiplin Belgorodskogo gosudarstvennogo natsional'nogo issledovatel'skogo universiteta

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