Aim. To analyze overall and new-onset osteoarthritis (OA) morbidity among the adult population in the Republic of Kazakhstan in 2011—2012. Subjects and methods. The data of annual statistical reports «On Population Health and Public Health System» (Form No. 12) in 2011—2012 were analyzed. The indicators in the Republic of Kazakhstan were taken from the statistical collected articles «Population Health in the Republic of Kazakhstan and Activities of Healthcare Facilities». Results. A comparative analysis of the indicators revealed a rising trend in overall morbidity by 1%, including in the incidence of musculoskeletal diseases (MSD) by 3% (the increase rate per 100,000 population was 2%). An analysis of the incidence of MSD per 100,000 population in some regions of the Republic of Kazakhstan showed an upward trend in the Almaty Region: the incidence increased among the women and the 18 or more year olds by 23 and 16%, respectively. Among the adults (aged 18 years or older) and women, the number of patients with a newly diagnosed coxarthrosis (CA) increased by 43 and 18%, respectively; the number of those with gonarthrosis (GA) rose by 36 and 33%, respectively. The people older than 60 years of age and women showed 122 and 82% rises in the number of patients with a newly diagnosed CA; there were 78% increment rates in the patients with GA and 68% in the women. Conclusion. In the Republic of Kazakhstan, there was a high incidence of OA in both the people aged 18 years or older with newly diagnosed CA, GA and the people over 60 years of age, in women in particular.