Cough: Differential diagnosis and rational pharmacotherapy

Close metadata

Recommended articles:

Pathoanatomical algorithm for differential diagnosis of Paget’s disease of the breast. Russian Journal of Archive of Pathology. 2023;(2):32-39

Hypersomnia in mental disorders. S.S. Korsakov Journal of Neurology and Psychiatry. 2023;(5-2):63-68

Intraplacental chorioncarcinoma: review of the literature and description of a clinical case. Russian Journal of Human Reproduction. 2023;(3):40-46

Myasthenic syndrome in a patient with end-stage amyotrophic lateral sclerosis. S.S. Korsakov Journal of Neurology and Psychiatry. 2023;(7):102-107

Punctate palmoplantar keratoderma, porokeratotic type. Russian Journal of Clinical Dermatology and Venereology. 2023;(4):441-446

Problems of chronic pelvic pain in modern gynecology. Russian Bulletin of Obstetrician-Gynecologist. 2023;(5):56-60

Symptom-oriented diagnostics as an important element in improving the quality of medical care. Russian Journal of Preventive Medicine. 2023;(9):7-10

Pulmonary benign metastasizing leiomyoma. Russian Journal of Preventive Medicine. 2023;(11):87-90

Advancing differential diagnosis in inflammatory bowel diseases: a combined model approach integrating erythrocyte parameters, inflammation markers, erythrocyte membranes fatty acids, and blood serum profiles. Russian Journal of Evidence-Based Gastroenterology. 2023;(4):75-88

On the issue of differential diagnosis of generalized pustular psoriasis and acute generalized exanthematous pustulosis. Russian Journal of Clinical Dermatology and Venereology. 2023;(6):758-763

This publication deals with topical problems in the management of patients with cough. It presents its epidemiology and clinical classification, an analysis of its causes, a list of required diagnostic techniques, and areas of pharmacotherapy. Emphasis is laid on the differential diagnosis of different abnormalities and diseases, the leading clinical sign of which is cough. The authors provide the detailed characteristics of medicaments for its treatment and the principles of rational antitussive and mucoactive pharmacotherapy.

Keywords:

cough

differential diagnosis

antitussive agents

mucoactive therapy

Authors:

A.A. Zaĭtsev

FGBUN "Tomskiĭ nauchno-issledovatel'skiĭ institut kurortologii i fizioterapii" Federal'nogo mediko-biologicheskogo agentstva Rossii

S.V. Okovityĭ

Poliklinika #91;
Sankt-Peterburgskaia gosudarstvennaia khimiko-farmatsevticheskaia akademiia, Sankt-Peterburg

List of references:

Morice A. Epidemiology of cough. Pulm Pharmacol Ther 2002; 15: 253-259.
Чучалин А.Г., Амбросимов В.Н. Kashel'. M: Ekho 2012; 128.
Morice A., McGarvey L., Pavord I. et al. Recommendations for the management of cough in adults. Thorax 2006; 61: 1-24.
Cullinan P. Persistent cough and sputum: prevalence and clinical characteristics in south east England. Respir Med 1992; 86: 143-149.
Lundback B., Nystrom L., Rosenhall L. et al. Obstructive lung disease in northern Sweden: respiratory symptoms assessed in a postal survey. Eur Respir J 1991; 4: 257-266.
Cerveri I., Accordini S., Corsico A. et al. Chronic cough and phlegm in young adults. Eur Respir J. 2003; 22 (3): 413-417.
Po dannym otchetov Federal'nogo gosudarstvennogo uchrezhdeniya zdravookhraneniya "Federal'nyi tsentr gigieny i epidemiologii Rospotrebnadzora RF". Dostupno na: http://www.fcgsen.ru/
Чучалин А.Г., Айсанов З.Р., Авдеев С.Н. и др. Federal'nye klinicheskie rekomendatsii po diagnostike i lecheniyu khronicheskoi obstruktivnoi bolezni legkikh. Moskva 2014. Dostupno na: http://www.pulmonology.ru/publications/ guide.php?clear_cache=Y
Чучалин А.Г., Айсанов З.Р., Белевский А.С. Federal'nye klinicheskie rekomendatsii po diagnostike i lecheniyu bronkhial'noi astmy. Moskva 2014. Dostupno na: http://www.pulmonology.ru/publications/guide.php
Синопальников А.И., Клячкина И.Л. Kashel'. M: Meditsinskoe informatsionnoe agentstvo 2013; 168.
Curley F., Irwin R., Pratter M. et al. Cough and the common cold. Am Rev Respir Dis 1988; 138: 305-311.
Ojoo J., Everett C., Mulrennan S. et al. Management of patients with chronic cough using a clinical protocol: a prospective observational study. Cough 2013; 9 (1): 2.
McCrory D., Coeytaux R., Yancy W. et al. Assessment and Management of Chronic Cough [Internet]. Aviable at: http://www.ncbi.nlm.nih.gov/pubmed/23367526
Зайцев А.А. Kashel'. Podkhody k diagnostike i lecheniyu. Consilium medicum 2013; 3: 50-54.
Синопальников А.И., Клячкина И.Л. Differentsial'nyi diagnoz. Kashel'. Consilium Medicum 2004; 10. Dostupno na: http://www.consilium-medicum.com/magazines/cm/medicum/article/12781
Frumkin K. Pertussis and Persistent Cough: Practical, Clinical and Epidemiologic Issues. J Emerg Med 2012; 12. 10. Aviable at: http://www.ncbi.nlm.nih.gov/pubmed/23287746
Оковитый С.В., Анисимова Н.А. Farmakologicheskie podkhody k protivokashlevoi terapii. Rus med zhurn 2011; 23: 1150-1158.
Клячкина И.Л. Vybor lekarstvennykh preparatov pri produktivnom kashle. Consilium Medicum. Pul'monologiya 2007; 1. Dostupno na: http://consilium-medicum.com/magazines/magazines/cm/pylmo/article/9569
Шмелева Н.М. Mukoreguliruyushchaya terapiya pri zabolevaniyakh organov dykhaniya: vozmozhnosti ambroksola. Consilium Medicum 2012; 11. Dostupno na: http://www.consilium-medicum.com/medicum/article/22064/
Клячкина И.Л. Lechenie kashlya pri ostroi respiratornoi infektsii i grippe u patsientov gruppy riska. Farmateka 2010; 5: 125-132.
Мещеряков В.В., Синевич О.Ю., Павлинова Е.Б. и др. Effektivnost' i bezopasnost' oral'noi formy sal'butamola (na primere preparata Askoril) v lechenii obostrenii bronkhial'noi astmy u detei. Pediatriya 2003; 6: 68-70.
Ровкина Е.И. Effektivnost' i bezopasnost' otkharkivayushchego lekarstvennogo sredstva Askoril. Novye SPb vrachebnye vedomosti 2000; 4: 54-55.
Ainapure S., Desai A., Korde K. Efficacy and safety of Ascoril in the management of cough - National Study Group report. J Indian Med Assoc 2001; 99: 111-114.
Jayaram S., Desai A. Efficacy and safety of Ascoril expectorant and other cough formula in the treatment of cough management in paediatric and adult patients - a randomized double-blind comparative trial. J Indian Med Assoc 2000; 98: 68-70.
Prabhu Shankar S., Chandrashekharan S., Bolmall C.S., Baliga V. Efficacy, safety and tolerability of salbutamol + guaiphenesin + bromhexine (Ascoril) expectorant versus expectorants containing salbutamol and either guaiphenesin or bromhexine in productive cough: a randomised control comparative study. J Indian Med Assoc 2010; 108: 313-320.
Амелина Е.Л., Анаев Э.Х., Красовский Л.К. и др. Mukoaktivnaya terapiya. Pod red. A.G. Chuchalina, A.S. Belevskogo. M: Atmosfera 2006; 127.

Close metadata