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E.N. Lyust

Perm State Pharmaceutical Academy, Russian Ministry of Health, Perm, Russia, 614070

E.Yu. Tumilovich

Perm State Pharmaceutical Academy, Russian Ministry of Health, Perm, Russia, 614070

Yu.N. Karpenko

Perm State Pharmaceutical Academy, Russian Ministry of Health, Perm, Russia, 614070

Optimization of the conditions for the  detection of psychoactive compounds of the cholinoblocker and antidepressant groups with the use of the  microcolumn HPLC technique

Authors:

E.N. Lyust, E.Yu. Tumilovich, Yu.N. Karpenko

More about the authors

Journal: Forensic Medical Expertise. 2015;58(3): 44‑47

DOI: 10.17116/sudmed201558344-47

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Table of contents

OPTIMIZATION OF THE CONDITIONS FOR THE DETECTION OF PSYCHOACTIVE COMPOUNDS OF THE CHOLINOBLOCKER AND ANTIDEPRESSANT GROUPS WITH THE USE OF THE MICROCOLUMN HPLC TECHNIQUE
OPTIMIZATION OF THE CONDITIONS FOR THE DETECTION OF PSYCHOACTIVE COMPOUNDS OF THE CHOLINOBLOCKER AND ANTIDEPRESSANT GROUPS WITH THE USE OF THE MICROCOLUMN HPLC TECHNIQUE

To cite this article:

Lyust EN, Tumilovich EYu, Karpenko YuN. Optimization of the conditions for the  detection of psychoactive compounds of the cholinoblocker and antidepressant groups with the use of the  microcolumn HPLC technique. Forensic Medical Expertise. 2015;58(3):44‑47. (In Russ.)
https://doi.org/10.17116/sudmed201558344-47

Подписка 2026 Судебно-медицинская экспертиза (Forensic Medical Expertise)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

The objective of the present study was to evaluate the possibility of using the BD-2003 database to separate the mixtures of various antidepressants by high-performance liquid chromatography (HPLC) based on the MiLiChrome A-02 complex with an EcoNova UV detector. The parameters of identification are described. The possibility of modification of the standard conditions for the analysis is demonstrated as exemplified by the identification of certain cholinoblockers. The proposed approach to the separation of  psychoactive preparations provides a basis for the development of  methods for the determination of these substances in biological tissues and fluids.

Keywords:

HPLC
antidepressants
cholinoblockers

Authors:

E.N. Lyust

Perm State Pharmaceutical Academy, Russian Ministry of Health, Perm, Russia, 614070

E.Yu. Tumilovich

Perm State Pharmaceutical Academy, Russian Ministry of Health, Perm, Russia, 614070

Yu.N. Karpenko

Perm State Pharmaceutical Academy, Russian Ministry of Health, Perm, Russia, 614070

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